Results 71 to 80 of about 2,002 (238)

Growth of C. jejuni NCTC 11168 and C. jejuni 81-176 wt and luxS mutants at 37°C and 42°C in BB: A–B C. jejuni NCTC 11168 wt/ΔluxS, C–D C. jejuni 81-176 wt/ΔluxS, E–F C. jejuni 81-176 wt/::luxS; black- wild type, red- luxS mutant; shown are the means ± SD (n = 3), _* -p<0.05 (Mann-Whitney-U test).

, 2014
Growth of C. jejuni NCTC 11168 and C. jejuni 81-176 wt and luxS mutants at 37°C and 42°C in BB: A–B C. jejuni NCTC 11168 wt/ΔluxS, C–D C. jejuni 81-176 wt/ΔluxS, E–F C. jejuni 81-176 wt/::luxS; black- wild type, red- luxS mutant; shown are the means ± SD
Soroush Sharbati (220009), Greta Gölz (610614), Linda Adler (610612), Thomas Alter (610613)   +3 more
core   +1 more source

A Transnasal Endoscope for Robotically Assisted Gastroscopy

Advanced Robotics Research, EarlyView.
This work introduces a 4.25 mm diameter magnetically navigated transnasal endoscope for upper gastrointestinal (GI) screening and intervention. The system enables precise remote steering throughout the upper GI tract and is demonstrated through in vitro and in vivo experiments, including the robotic execution of preprogrammed retroflexions, trans ...
Alexandre Mesot, Michelle Mattille, Sean Lyttle, Shannon M. Chan, Philip W. Y. Chiu, Quentin Boehler, Bradley J. Nelson   +6 more
wiley   +1 more source

Virtual Screening and Biological Evaluation of Anti-Biofilm Agents Targeting LuxS in the Quorum Sensing System

Natural Product Communications, 2021
Biofilm formation is considered as a crucial factor in various oral diseases, such as dental caries. The quorum sensing (QS) signaling system was proved to have a crucial role in the microbial dental plaque biofilm formation of Streptococcus mutans ( S ...
Zheng Liu, Lihua Zhang, Jincai Wang, Yanping Li, Yiqun Chang, Xiaoling Huang, Jun Duan, Yilong Ai, Xuxin Zeng, Jialiang Guo   +9 more
doaj   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

Enhanced bioethanol production by Zymomonas mobilis in response to the quorum sensing molecules AI-2 [PDF]

, 2011
The depletion of non-renewable energy resources, the environmental concern over the burning of fossil fuels, and the recent price rises and instability in the international oil markets have all combined to stimulate interest in the use of fermentation ...
Yang, Jung Woo, YANG, JUNG,WOO
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Phenotypes of Campylobacter jejuni luxS mutants are depending on strain background, kind of mutation and experimental conditions.

PLoS ONE, 2014
Since the discovery that Campylobacter (C.) jejuni produces Autoinducer 2 (AI-2), various studies have been conducted to explore the function and role of AI-2 in C. jejuni. However, the interpretation of these analyses has been complicated by differences
Linda Adler, Thomas Alter, Soroush Sharbati, Greta Gölz   +3 more
doaj   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Baicalin Weakens the Virulence of Porcine Extraintestinal Pathogenic Escherichia coli by Inhibiting the LuxS/AI-2 Quorum-Sensing System

Biomolecules
Porcine extraintestinal pathogenic Escherichia coli (ExPEC) is a pathogenic bacterium that causes huge economic losses to the pig farming industry and considerably threatens human health.
Bingbing Zong, Yong Xiao, Peiyi Wang, Wei Liu, Mingxing Ren, Changyan Li, Shulin Fu, Yanyan Zhang, Yinsheng Qiu   +8 more
doaj   +1 more source