Results 21 to 30 of about 161 (74)

PLA₂ Inhibitor Varespladib as an Alternative to the Antivenom Treatment for Bites from Nikolsky's Viper Vipera berus nikolskii. [PDF]

Toxins (Basel), 2020
Zinenko O, Tovstukha I, Korniyenko Y.
europepmc   +1 more source

Macrophage polarization is linked to Ca²⁺-independent phospholipase A₂β-derived lipids and cross-cell signaling in mice. [PDF]

J Lipid Res, 2020
Nelson AJ, Stephenson DJ, Cardona CL, Lei X, Almutairi A, White TD, Tusing YG, Park MA, Barbour SE, Chalfant CE, Ramanadham S.   +10 more
europepmc   +1 more source

Evaluation of Protection by Caffeic Acid, Chlorogenic Acid, Quercetin and Tannic Acid against the In Vitro Neurotoxicity and In Vivo Lethality of Crotalus durissus terrificus (South American Rattlesnake) Venom. [PDF]

Toxins (Basel), 2021
Oliveira ICF, Yoshida EH, Dini MMJ, Paschoal ABO, Cogo JC, da Cruz-Höfling MA, Hyslop S, Oshima-Franco Y.   +7 more
europepmc   +1 more source

Substrate-Specific Inhibition Constants for Phospholipase A₂ Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]

J Med Chem, 2019
Mouchlis VD, Armando A, Dennis EA.
europepmc   +1 more source

Allosteric regulation by membranes and hydrophobic subsites in phospholipase A₂ enzymes determine their substrate specificity. [PDF]

J Biol Chem, 2022
Dennis EA.
europepmc   +1 more source

In Silico Evaluation of Quercetin Methylated Derivatives on the Interaction with Secretory Phospholipases A2 from Crotalus durissus terrificus and Bothrops jararacussu. [PDF]

Pharmaceuticals (Basel), 2023
Belchor MN, Costa CRDC, Roggero A, Moraes LLF, Samelo R, Annunciato I, de Oliveira MA, Sousa SF, Toyama MH.   +8 more
europepmc   +1 more source

Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A₂ inhibitors. [PDF]

Adv Biol Regul, 2020
Mouchlis VD, Mu C, Hammons R, Dennis EA.
europepmc   +1 more source

Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan Oxyuranus scutellatus Venoms. [PDF]

Toxins (Basel), 2023
Gilliam LL, Gilliam J, Samuel SP, Carter RW, Ritchey J, Bulfone T, Gutiérrez JM, Williams DJ, Durkin DM, Stephens SI, Lewin MR.   +10 more
europepmc   +1 more source

The Need for Next-Generation Antivenom for Snakebite Envenomation in India. [PDF]

Toxins (Basel), 2023
Vanuopadath M, Rajan K, Alangode A, Nair SS, Nair BG.   +4 more
europepmc   +1 more source

Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2.

Journal of Medicinal Chemistry, 2008
Rob C. Oslund, N. Cermak, M. Gelb
semanticscholar   +1 more source