Results 11 to 20 of about 1,603 (190)

Reference gene selection for real‐time quantitative PCR assays in different tissues of Huperzia serrata based on full‐length transcriptome sequencing

Plant Direct, 2021
Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu, Fei Niu, Hui Jia, Yanli Wang, Bin Guo, Yahui Wei   +5 more
doaj   +2 more sources

Strategies and Efforts towards the Total Synthesis of Palhinine Alkaloids

Molecules, 2020
The palhinine family of Lycopodium alkaloids were first reported in 2010, which feature an intriguing isotwistane carbon cage and a nine-membered azonane ring.
Yu-Yan Liang, Shi-Chao Lu, Ya-Ling Gong, Shu Xu   +3 more
doaj   +1 more source

Highlighting the Rich Chemistry of the Allenone Moiety

Advanced Synthesis &Catalysis, Volume 365, Issue 9, Page 1332-1384, May 12, 2023., 2023
Abstract Conjugated and non‐conjugated allenones appear as recurring motifs in organic synthesis, natural products and mechanistic investigations showing unique properties and applications. The ability of allenones to build cycles has provided a direct access to strained systems, medium‐sized rings, arenes, heterocycles and complex polycycles.
José M. Alonso, Pedro Almendros
wiley   +1 more source

Skeletal Editing: Interconversion of Arenes and Heteroarenes

Helvetica Chimica Acta, Volume 106, Issue 3, March 2023., 2023
Abstract Skeletal editing involves making specific point‐changes to the core of a molecule through the selective insertion, deletion or exchange of atoms. It thus represents a potentially powerful strategy for the step‐economic modification of complex substrates and is a perfect complement to methods such as C−H functionalization that target the ...
Ben W. Joynson, Liam T. Ball
wiley   +1 more source

Early land plants: Plentiful but neglected nutritional resources for herbivores?

Ecology and Evolution, Volume 12, Issue 12, December 2022., 2022
In this paper, we explore the unknown reason(s) why herbivores rarely seem to attack early land plants like mosses and ferns. Our study, in which we looked at the performance of an arthropod and a gastropod on 15 species of such plants, yields surprising results that disqualify some of the common notions about early land plants.
Audrey Duhin, Ricardo A. R. Machado, Ted C. J. Turlings, Gregory Röder   +3 more
wiley   +1 more source

Fractionation of Lycopodiaceae Alkaloids and Evaluation of Their Anticholinesterase and Cytotoxic Activities

Molecules, 2021
In view of the abundant evidence that Lycopodiaceae alkaloids, including the well-known huperzine A (HupA), are among the potent acetylcholinesterase (AChE) inhibitors, an attempt was made to search for new compounds responsible for this property.
Aleksandra Dymek, Jarosław Widelski, Krzysztof Kamil Wojtanowski, Vladyslav Vivcharenko, Agata Przekora, Tomasz Mroczek   +5 more
doaj   +1 more source

Bioactive Compounds and Their Derivatives: An Insight into Prospective Phytotherapeutic Approach against Alzheimer’s Disease

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Alzheimer’s disease (AD) is a common neurodegenerative brain disorder that causes cellular response alterations, such as impaired cholinergic mechanism, amyloid‐beta (Aβ) AD aggregation, neuroinflammation, and several other pathways. AD is still the most prevalent form of dementia and affects many individuals across the globe.
Fahadul Islam, Jannatul Fardous Khadija, Md. Harun-Or-Rashid, Md. Saidur Rahaman, Mohamed H. Nafady, Md. Rezaul Islam, Aklima Akter, Talha Bin Emran, Polrat Wilairatana, Mohammad S. Mubarak, Sachchida Nand Rai   +10 more
wiley   +1 more source

In Vitro Bioactivities of Plants Used against Skin Diseases in the Eastern Free State, South Africa

International Journal of Plant Biology, 2023
Skin diseases are a worldwide issue, accounting for approximately 34% of all occupational illnesses. The aim of this study was to investigate medicinal plants used to treat wounds and skin diseases in the eastern Free State Province of South Africa.
Valeria Makhosazana Xaba, Ariyo Lateef Adeniran, Siphamandla Qhubekani Njabuliso Lamula, Lisa Valencia Buwa-Komoreng   +3 more
doaj   +1 more source

Biogenic Phytochemicals Modulating Obesity: From Molecular Mechanism to Preventive and Therapeutic Approaches

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
The incidence of obesity and over bodyweight is emerging as a major health concern. Obesity is a complex metabolic disease with multiple pathophysiological clinical conditions as comorbidities are associated with obesity such as diabetes, hypertension, cardiovascular disorders, sleep apnea, osteoarthritis, some cancers, and inflammation‐based clinical ...
Vikram Kumar, Desh Deepak Singh, Sudarshan Singh Lakhawat, Nusrath Yasmeen, Aishwarya Pandey, Rajeev K. Singla, Gabriel A. Agbor   +6 more
wiley   +1 more source

Oxidation of cadaverine by putrescine oxidase from Rhodococcus erythropolis

Journal of Chemical Technology &Biotechnology, Volume 96, Issue 10, Page 2950-2955, October 2021., 2021
Abstract BACKGROUND Putrescine oxidase (EC 1.4.3.10) is of interest for the microbial production of unsubstituted platform nitrogen (N‐)heterocycles, because it only requires inexpensive oxygen as co‐substrate. Putrescine oxidase from Rhodococcus erythropolis (Re‐PuO) was shown previously to catalyze the oxidation of cadaverine; however, there is ...
Valentine E Anyanwu, Stephen J Hall, Gill Stephens, Anca Pordea   +3 more
wiley   +1 more source