Results 11 to 20 of about 479 (139)

Reference gene selection for real‐time quantitative PCR assays in different tissues of Huperzia serrata based on full‐length transcriptome sequencing

open access: yesPlant Direct, 2021
Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu   +5 more
doaj   +2 more sources

Comprehensive relative quantitative metabolomics analysis of lycopodium alkaloids in different tissues of Huperzia serrata. [PDF]

open access: yesSynth Syst Biotechnol, 2018
Qian ceng Ta, the whole plant of Huperzia serrata, is an important landscape and medicinal herbs and contains abundant bioactive lycopodium alkaloids. Although the structures of more than 100 lycopodium alkaloids in Huperzia serrata have been isolated ...
Wu S, Fan Z, Xiao Y.
europepmc   +2 more sources

Lycodine-Type Lycopodium Alkaloids from the Whole Plants of Huperzia serrata. [PDF]

open access: yesNat Prod Bioprospect, 2017
Three new lycodine-type Lycopodium alkaloids, namely 1-methyllycodine (1), 8α-hydroxy-15,16-dehydro-des-N-methyl-α-obscurine (2), N-methyl-16-hydroxyhuperzine B (3), and one new natural lycodine-type Lycopodium alkaloid, N-methylhuperzine A (4), along ...
Liu YC   +6 more
europepmc   +2 more sources

Enantioselective total synthesis of lycoposerramine congeners through late-stage nitrogen deletion. [PDF]

open access: yesNat Commun
Lycopodium alkaloids are attractive synthetic targets due to their diverse and unusual skeletal features. While numerous synthetic approaches have been reported, there still remain outstanding synthetic challenges to several lycopodium alkaloids. Herein,
Yokoi K, Renata H.
europepmc   +2 more sources

Lycocasine A, a Lycopodium Alkaloid from Lycopodiastrum casuarinoides and Its Acid-Sensing Ion Channel 1a Inhibitory Activity. [PDF]

open access: yesMolecules
A novel Lycopodium alkaloid, lycocasine A (1), and seven known Lycopodium alkaloids (2–8), were isolated from Lycopodiastrum casuarinoides. Their structures were determined through NMR, HRESIMS, and X-ray diffraction analysis.
Jiang S, Li WY, Gao BB, Zhao QS.
europepmc   +2 more sources

Strategies and Efforts towards the Total Synthesis of Palhinine Alkaloids

open access: yesMolecules, 2020
The palhinine family of Lycopodium alkaloids were first reported in 2010, which feature an intriguing isotwistane carbon cage and a nine-membered azonane ring.
Yu-Yan Liang   +3 more
doaj   +1 more source

Optimization of Pressurized Liquid Extraction of Lycopodiaceae Alkaloids Obtained from Two Lycopodium Species

open access: yesMolecules, 2021
Alkaloids of the Lycopodiaceae family are of great interest to researchers due to their numerous properties and wide applications in medicine. They play a very important role mainly due to their potent antioxidant, antidepressant effects and a reversible
Aleksandra Dymek   +5 more
doaj   +1 more source

Fractionation of Lycopodiaceae Alkaloids and Evaluation of Their Anticholinesterase and Cytotoxic Activities

open access: yesMolecules, 2021
In view of the abundant evidence that Lycopodiaceae alkaloids, including the well-known huperzine A (HupA), are among the potent acetylcholinesterase (AChE) inhibitors, an attempt was made to search for new compounds responsible for this property.
Aleksandra Dymek   +5 more
doaj   +1 more source

Highlighting the Rich Chemistry of the Allenone Moiety

open access: yesAdvanced Synthesis &Catalysis, Volume 365, Issue 9, Page 1332-1384, May 12, 2023., 2023
Abstract Conjugated and non‐conjugated allenones appear as recurring motifs in organic synthesis, natural products and mechanistic investigations showing unique properties and applications. The ability of allenones to build cycles has provided a direct access to strained systems, medium‐sized rings, arenes, heterocycles and complex polycycles.
José M. Alonso, Pedro Almendros
wiley   +1 more source

In Vitro Bioactivities of Plants Used against Skin Diseases in the Eastern Free State, South Africa

open access: yesInternational Journal of Plant Biology, 2023
Skin diseases are a worldwide issue, accounting for approximately 34% of all occupational illnesses. The aim of this study was to investigate medicinal plants used to treat wounds and skin diseases in the eastern Free State Province of South Africa.
Valeria Makhosazana Xaba   +3 more
doaj   +1 more source

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