Results 61 to 70 of about 2,205 (198)

Thiophenderivate als vielseitige Vorstufen für die Synthese von (Hetero)aromaten und Naturstoffen

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Verborgen, aber leistungsstark: Thiophene und ihre gesättigten Analoga haben sich als vielseitige C4‐Bausteine erwiesen, die sich effektiv in der Naturstoffsynthese sowie beim Aufbau funktionalisierter (Hetero)aromaten einsetzen lassen. Dieser Minireview soll einen Überblick über Strategien zur Anwendung dieser schwefelhaltigen heterozyklischen ...
Anna Keimer, Franz‐Lucas Haut
wiley   +1 more source

Lycorine impedes 7,12-dimethylbenz(a)anthracene exposed hamster oral carcinogenesis through P13K/Akt and NF-κB inhibition

Türk Biyokimya Dergisi, 2022
Oncogenic signaling pathways that are activated abnormally play a key activity in tumor initiation and development. This research aimed to examine the preventive efficiency of lycorine in the buccal pouch hamster tumor model based on its capacity to ...
Gan Yi, He Ai’e, Zhu Lilei, Yao Yao, Lv Chunhua   +4 more
doaj   +1 more source

Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis

Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley   +1 more source

Preparation of lycorine derivatives and their biological activity [PDF]

, 2018
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Botany Candidate: Kamila Lipovská Supervisor: doc. Ing. Lucie Cahlíková, Ph.D.
Lipovská, Kamila
core  

Molecular Mechanisms of Anti‐Inflammatory and Immunomodulatory Activities of Key Phytochemicals: A Comprehensive Review

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Phytochemicals derived from medicinal plants represent a rich and largely underexploited source of anti‐inflammatory and immunomodulatory agents. Chronic inflammation and dysregulated immune responses underpin many tropical and global diseases, including infectious, autoimmune, and metabolic disorders. This review examines the spectrum of plant‐derived
Md Asaduzzaman, Lutfun Nahar, Mohammad Shahangir Biswas, Md. Matiar Rahman, Zhengwei Huang   +4 more
wiley   +1 more source

Lycorine Promotes Autophagy and Apoptosis via TCRP1/Akt/mTOR Axis Inactivation in Human Hepatocellular Carcinoma

, 2017
Lycorine is a multifunctional bioactive compound, and it possesses potential anticancer activities. However, little is known about the underlying mechanism.
Chengyun Jin, Jian Li, Yuling Qiu, Xiumei Gao, Wenwei Hu, Tao Wang, Song Wu, Lifeng Han, Shuangshuang Yin, Xu Pang, Yi Zhang, Haiyang Yu   +11 more
core   +1 more source

Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang, Yuqian Liu, Shuying Ren, Zhouyuan Wang, Yunxia Li, Lianci Peng, Rendong Fang, Jianchao Wei   +7 more
wiley   +1 more source

Environmental and phytohormone modulation of organ‐specific specialized metabolite profiles in the dryland tree Erythrina velutina

Plant Biology, Volume 27, Issue 7, Page 1326-1340, December 2025.
Erythrina velutina organ‐specific specialized metabolism is modulated by environmental stress and phytohormones to mitigate effects of the harsh semi‐arid habitat. Abstract Erythrina velutina is a tree that thrives in the shallow rocky soils of the dry and hot Caatinga, a unique Brazilian biome.
D. S. Chacon, B. Bonilauri, C. T. da Costa, J. Vilasboa, M. Koetz, L. Pinto, J. A. S. Zuanazzi, R. B. Giordani, A. G. Fett‐Neto   +8 more
wiley   +1 more source

Supplementary Figures 1-12 from Lycorine Promotes Autophagy and Apoptosis via TCRP1/Akt/mTOR Axis Inactivation in Human Hepatocellular Carcinoma

, 2017
Supplementary Figure 1. Lycorine has no apparent effect on body weight in nude mice; Supplementary Figure 2. Lycorine induces apoptosis via caspase-dependent pathway; Supplementary Figure 3. Lycorine induces autophagy in HuH-7 cells; Supplementary Figure
Yi Zhang (9093), Chengyun Jin (15071740), Xiumei Gao (221817), Xu Pang (2552470), Shuangshuang Yin (5612591), Wenwei Hu (337307), Yuling Qiu (332854), Tao Wang (12008), Haiyang Yu (543050), Jian Li (41607), Song Wu (36667), Lifeng Han (375604)   +11 more
core   +1 more source

Preclinical Screening Platform Identifies Azatadine‐Dimaleate as a Potent Repurposed Therapeutic Against SARS‐CoV‐2 Infection

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT The emergence of SARS‐CoV‐2 posed a major global public health threat, necessitating urgent development of therapeutics. Despite vaccine availability, continuous emergence of viral variants with enhanced transmissibility and immune escape capabilities, and consequential impacts on health services, requires effective antiviral therapeutics ...
Ahlam Ali, David Courtney, Lindsay Broadbent, Parul Sharma, Connor G. G. Bamford, Sheerien Manzoor, Olivier Touzelet, Conall McCaughey, Adam Kirby, Eleanor Bentley, Anja Kipar, Ken I. Mills, James P. Stewart, Ultan F. Power   +13 more
wiley   +1 more source