Results 171 to 180 of about 770,345 (334)

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

Advanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu, Minmin Zhang, Qinqin Huang, Song Gao, Sitong Chu, Qi Li, Wanyao Chen, Xinglong Zhang, Tianfu Zhang, Ben Zhong Tang, Shipeng Ning   +10 more
wiley   +1 more source

THE SIGNIFICANCE OF ABERRANT OF HETEROTOPIC PAROTID GLAND TISSUE IN LYMPH NODES*

, 1953
R Brown, Romy Gaillard, James A. Turner
openalex   +2 more sources

The selection of axillary lymph nodes in radical-mastectomy specimens [PDF]

, 1957
Benjamin H. Dunn, Bruce A. Elrod
openalex   +1 more source

Self‐Powered α Radionuclide Nanomedicine: Mitochondria‐Targeted Multimodal Energy Recycling for Amplified Radioimmunotherapy

Advanced Materials, EarlyView.
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li, Chaochao Wang, Yelin Wu, Jiajia Zhang, Han Zhang, Shanshan Qin, Linglin Tang, Fei Yu   +7 more
wiley   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

Advanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash, Waleed M. Hussein, Ummey J. Nahar, Jingwen Wang, Lantian Lu, Armira Azuar, Jolynn J. E. Kiong, Prashamsa Koirala, Zeinab G. Khalil, Istvan Toth   +9 more
wiley   +1 more source

Deep learning assisted non-invasive lymph node burden evaluation and CDK4/6i administration in luminal breast cancer

iScience
Summary: Precise lymph node evaluation is fundamental to optimize CDK4/6 inhibitor therapy in luminal breast cancer, particularly given contemporary trends toward axillary surgery de-escalation that may compromise traditional lymph node staging for ...
Yuhan Liu, Jinlin Ye, Zecheng He, Mingyue Wang, Changjun Wang, Jie Lang, Yidong Zhou, Wei Zhang   +7 more
doaj  

Assessment of the dose Reaching the Lymph Nodes Along the Pelvic Wall, as Measured in Studies Made at Extraperitoneal Lymphadenectomy [PDF]

, 1953

openalex   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Sentinel Lymph Node Biopsy Predicts Non-Sentinel Lymph Node Metastases and Supports Omission of Axillary Lymph Node Dissection in Breast Cancer Patients. [PDF]

J Clin Med
Yoneto T, Ikiuo F, Koyanagi N, Yoshimoto T, Takeda Y.   +4 more
europepmc   +1 more source

DISTRIBUTION OF ANTIBODY-FORMING CELLS OF DIFFERENT SPECIFICITIES IN THE LYMPH NODES AND SPLEENS OF GUINEA PIGS [PDF]

, 1968
Ira Green
openalex   +1 more source