Results 131 to 140 of about 764,268 (348)

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

The Comparative Study of Lymph Node Dissection by Video-assisted Thoracoscopic Surgery (VATS) and Conventional Lateral Incision Surgery

Chinese Journal of Lung Cancer, 2010
Background and objective Although widely adopted, there is lack of comparative data for patients undergoing lymph node dissection in radical surgery of lung cancer by video-assisted thoracoscopic surgery (VATS) vs conventional lateral incision surgery ...
Qiang LI, Jintao HE, Xiang ZHUANG, Xiaojun YANG, Jiang ZHU, Tianpeng XIE, Ping XIAO, Xiang WANG, Hao RONG   +8 more
doaj  

The Antibody Response of Lymph Node Cells Transferred to Tolerant Recipients [PDF]

, 1959
William O. Weigle, Frank J. Dixon
openalex   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

A Study on Lymph Node Distribution in the Main Lymph Node Area for Left-sided Colon Cancer

Journal of the Anus, Rectum and Colon
Objectives: In advanced left-sided colorectal cancer, cutting the root of the inferior mesenteric artery (IMA) branching from the aorta is recommended for complete lymph node dissection. However, this procedure sometimes causes severe complications. This
Fumiki Koga, Fumihiko Fujita, Takefumi Yoshida, Kenichi Koushi, Naohiro Yoshida, Takahiro Shigaki, Kenji Fujiyoshi, Naoki Mori, Tomoya Sudou, Jun Akiba, Nobuya Ishibashi, Touru Hisaka   +11 more
doaj   +1 more source

Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]

, 2018
There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin, Alecu, Lucian, Cristian, Balalau, Hainarosie, Razvan, Jecan, Radu, Nitipir, Cornelia, Orlov, Cristina, Pantea Stoian, Anca, Pituru, Silviu, Poiana, Catalina, Slavu, Iulian, Tomescu, Luminita, Tulin, Raluca   +12 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

CT texture analysis can help differentiate between malignant and benign lymph nodes in the mediastinum in patients suspected for lung cancer [PDF]

, 2016
BACKGROUND: In patients with non-small-cell lung carcinoma NSCLC the lymph node staging in the mediastinum is important due to impact on management and prognosis. Computed tomography texture analysis (CTTA) is a postprocessing technique that can evaluate
Andersen, MB, Ganeshan, B, Harders, SW, Rasmussen, F, Thygesen, J, Torp Madsen, HH   +5 more
core  

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Use of intraoperative luminescent methods for detecting affected lymph nodes in patients with complicated forms of colon cancer

Сучасні медичні технології
The issue of the volume of lymphatic dissection in patients with complicated forms of colon cancer and the possibility of using methods of intraoperative visualisation of the affected lymph nodes remains controversial.
M. A. Kubrak, S. M. Zavhorodnii, M. B. Danyliuk, A. I. Rylov   +3 more
doaj   +1 more source