Results 81 to 90 of about 33,222 (220)
Obesity Alters the Vascular Morphology and VEGF‐A Signaling in Adipose Tissue
FASEB BioAdvances, EarlyView.Obesity alters cell geometry and vessel morphology in mice adipose tissue by increasing adipocyte size by 78% and reducing vessel density by 51%, while vessel size and capillary basement membrane thickness remain unchanged. Obesity also affects angiogenesis, which is mediated by vascular endothelial growth factor (VEGF) binding kinetics.
Yunjeong Lee +5 more
wiley +1 more source
Lymphangiogenesis and cancer metastasis
Frontiers in Bioscience, 2011 Lymphangiogenesis remains a fascinating biological process that plays a crucial role in both normal tissue development and several lymphatic diseases. The last few years have witnessed a rapid progression in understanding the development and regulation of the lymphatic system which provided insight on several pathological processes including cancer ...
A. A. Mahir Al-Rawi, Wen Guo Jiang
openaire +2 more sources
Arteriosclerosis, Thrombosis and Vascular Biology, 2021 Supplemental Digital Content is available in the text. Objective: Thromboxane is an arachidonic acid metabolite that exerts its actions through a G-protein–coupled receptor with 7 transmembrane domains.
Hiromi Matsuda +10 more
semanticscholar +1 more source
A Review of Mathematical Models for the Formation of\ud Vascular Networks [PDF]
, 2012 Mainly two mechanisms are involved in the formation of blood vasculature: vasculogenesis and angiogenesis. The former consists of the formation of a capillary-like network from either a dispersed or a monolayered population of endothelial cells ...
Bell, C. G., Preziosi, L., Scianna, M.
core
Exercise‐Induced Cardiac Lymphatic Remodeling Mitigates Inflammation in the Aging Heart
Aging Cell, EarlyView.Exercise improves cardiac lymphatic architecture and function in the aged mouse. Aged hearts show reduced lymphatic vascular density, more dilated vessels, and increased peri‐lymphatic inflammation and fibrosis. Exercise training of the aged mouse increases lymph vessel density and sprouting, reverses their dilation, reduces inflammation and fibrosis ...
Kangsan Roh +19 more
wiley +1 more source
Mast Cells, Angiogenesis and Lymphangiogenesis in Human Gastric Cancer
International Journal of Molecular Sciences, 2019 Gastric cancer is diagnosed in nearly one million new patients each year and it remains the second leading cause of cancer-related deaths worldwide. Although gastric cancer represents a heterogeneous group of diseases, chronic inflammation has been shown
G. Sammarco +11 more
semanticscholar +1 more source
PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor
Cell Death and Disease, 2021 Nasopharyngeal carcinoma (NPC) is one of the most malignant tumors in southern China and Asia, and lymph node metastasis is an important cause for treatment failure.
Chuanghua Luo +13 more
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose The C‐type lectin‐like receptor‐2 (CLEC‐2) is a platelet receptor for the endogenous ligand podoplanin. This interaction contributes to several (patho)physiological processes, such as lymphangiogenesis, preservation of blood and lymphatic vessel integrity organ development, and tumour metastasis.
Marcin A. Sowa +8 more
wiley +1 more source
Cancer Science, Volume 116, Issue 4, Page 936-950, April 2025.This study unveiled the mechanism wherein IGF2BP3 was overexpressed in human LUAD tissues, promoted cell migration and invasion, EMT, lymphangiogenesis, and lymph node metastasis by binding the m6A site of the 3′UTR region of SRC and maintaining its stability to activate STAT3 signaling pathway, and promote VEGFC expression in LUAD.
Jiapei Ding +7 more
wiley +1 more source
Theranostics, 2020 Collagen and calcium-binding EGF domain-1 (CCBE1) is essential for lymphatic vascular development as it promotes vascular endothelial growth factor C (VEGFC) proteolysis.
Jinglue Song +8 more
semanticscholar +1 more source