A translocated effector required for bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors [PDF]
Numerous bacterial pathogens secrete multiple effectors to modulate host cellular functions. These effectors may interfere with each other to efficiently control the infection process.
Okujava, Rusudan +54 more
core +2 more sources
Slit2/Robo4 signaling modulates HIV-1 gp120-induced lymphatic hyperpermeability.
Dissemination of HIV in the host involves transit of the virus and virus-infected cells across the lymphatic endothelium. HIV may alter lymphatic endothelial permeability to foster dissemination, but the mechanism is largely unexplored.
Xuefeng Zhang +5 more
doaj +1 more source
Apolipoprotein A‐I Modulates Atherosclerosis Through Lymphatic Vessel‐Dependent Mechanisms in Mice
BackgroundSubcutaneously injected lipid‐free apoA‐I (apolipoprotein A‐I) reduces accumulation of lipid and immune cells within the aortic root of hypercholesterolemic mice without increasing high‐density lipoprotein–cholesterol concentrations.
Andreea Milasan +6 more
doaj +1 more source
FACS of patient-matched CD133+ and CD133− LM cells isolated from microcystic mesenteric (Micro Mes) LM, microcystic subcutaneous (Micro SC) LM and general lymphatic anomaly (GLA) specimens. (A) Endothelial precursor markers, CD34, CD90, CD146 and VEGFR-2.
John P. Andrews (696271) +10 more
core +1 more source
Notch Signaling Determines Lymphatic Cell Fate and Regulates Sprouting Lymphangiogenesis [PDF]
The lymphatic vascular system is necessary for physiological regulation of tissue fluid homeostasis and absorption of dietary fat. Lymphatics also function in the inflammatory response and are involved in pathological conditions such as wound healing and
Uh, Minji
core +1 more source
PMab-235: A monoclonal antibody for immunohistochemical analysis against goat podoplanin
Sensitive and specific monoclonal antibodies (mAbs) against not only human but also mouse, rat, rabbit, dog, cat, bovine, pig, and horse podoplanins (PDPNs) have been established in our previous studies.
Yoshikazu Furusawa +10 more
doaj +1 more source
Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions [PDF]
Primitive lymphatic vessels are remodeled into functionally specialized initial and collecting lymphatics during development. Lymphatic endothelial cell (LEC) junctions in initial lymphatics transform from a zipper-like to a button-like pattern during ...
W. Zheng +44 more
core +1 more source
Establishment and Characterization of a Human Lymphatic Endothelial Cell Line
Lymphatic endothelial cell (LEC) culture is associated with several problems. There are ethical concerns about the collection of LECs from humans, in addition to the concern that LECs from different individuals might exhibit variable behavior. Properties of LECs such as morphology can also change when they are cultured for prolonged periods.
Nakamura, Ryosuke +5 more
openaire +3 more sources
Changes in the desmosomes of lymphatic vessel endothelial cells as shown by electron microscopy.
(a) Desmosomes in the normal type. In a three-dimensional structure, they adhere to the adjacent lymphatic vessel endothelial cells. Bar = 2 µm. (a’) Magnified image. Bar = 2 µm.
Takeshi Todokoro (314536) +13 more
core +1 more source
Lymphangiogenesis in post-natal tissue remodeling: Lymphatic endothelial cell connection with its environment. [PDF]
peer reviewedThe main physiological function of the lymphatic vasculature is to maintain tissue fluid homeostasis. Lymphangiogenesis or de novo lymphatic formation is closely associated with tissue inflammation in adults (i.e.
Paupert, Jenny +5 more
core +1 more source

