Results 61 to 70 of about 5,519,715 (191)

Digging deeper into lymphatic vessel formation in vitro and in vivo

BMC Cell Biology, 2011
Background Abnormal lymphatic vessel formation (lymphangiogenesis) is associated with different pathologies such as cancer, lymphedema, psoriasis and graft rejection.
Thiry Marc, Foidart Jean-Michel, Lenoir Bénédicte, Maillard Catherine, Lamaye Françoise, Paupert Jenny, Erpicum Charlotte, Bruyère Françoise, Detry Benoit, Noël Agnès   +9 more
doaj   +1 more source

VEGFR3 is required for button junction formation in lymphatic vessels

Cell Reports, 2023
Summary: Lymphatic capillaries develop discontinuous cell-cell junctions that permit the absorption of large macromolecules, chylomicrons, and fluid from the interstitium.
Melanie Jannaway, Drishya Iyer, Diandra M. Mastrogiacomo, Kunyu Li, Derek C. Sung, Ying Yang, Mark L. Kahn, Joshua P. Scallan   +7 more
doaj   +1 more source

Lymphatic endothelial cell immunohistochemical markers for evaluation of the intestinal lymphatic vasculature in dogs with chronic inflammatory enteropathy

Journal of Veterinary Internal Medicine, 2019
Background Lymphatic endothelial cell (LEC) immunohistochemical markers have identified intestinal lymphatic vasculature abnormalities in humans with inflammatory bowel disease, but have not been used to evaluate intestinal lymphatic vasculature in a ...
Sara A. Jablonski Wennogle, Simon L. Priestnall, Alejandro Suárez‐Bonnet, Sirikul Soontararak, Craig B. Webb   +4 more
doaj   +1 more source

Single-cell RNA sequencing reveals cellular and molecular landscape of fetal cystic hygroma

BMC Medical Genomics
Background The molecular mechanism of fetal cystic hygroma (CH) is still unclear, and no study has previously reported the transcriptome changes of single cells in CH.
Fang Fu, Xin Yang, Ru Li, Yingsi Li, Hang Zhou, Ken Cheng, Ruibin Huang, You Wang, Fei Guo, Lina Zhang, Min Pan, Jin Han, Li Zhen, Lushan Li, Tingying Lei, Dongzhi Li, Can Liao   +16 more
doaj   +1 more source

Shaping of Peripheral T Cell Responses by Lymphatic Endothelial Cells [PDF]

Frontiers in Immunology, 2017
Lymph node stromal cells (LNSCs) have newly been promoted to the rank of new modulators of T cell responses. The different non-hematopoietic cell subsets in lymph node (LN) were considered for years as a simple scaffold, forming routes and proper environment for antigen (Ag)-lymphocyte encountering.
Humbert, Marion, Hugues, Stéphanie, Dubrot Armendariz, Juan   +2 more
openaire   +3 more sources

Mechanism of Alcohol Induced Mesenteric Lymphatic Vessel Leakage

Revista Cubana de Investigaciones Biomédicas, 2020
Introduction: Lymphatic vessels are involved in the trafficking of immune cells and play a role in antigen transport and immune cell regulatory functions.
Flavia Souza-Smith, Matthew Herrera, Liz Simon, Patricia Molina   +3 more
doaj  

Reconstruction of lymphatic vessels in the mouse tail after cupping therapy

Folia Morphologica, 2020
Background: The aim of the study was to investigate the regulatory mechanism of local lymphatic reconstruction after cupping therapy in a mouse model. Materials and methods: The lymphatic reconstruction process in the mouse tail after cupping therapy as ...
F.-W. Meng, Z.-L. Gao, L. Li, L.-L. Jie, P.-F. Yang, Z. Liang, Y.-W. Gao, W.-H. Liu   +7 more
doaj   +1 more source

PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations

PLOS ONE, 2018
Lymphatic malformations (LM) are characterized by the overgrowth of lymphatic vessels during pre- and postnatal development. Macrocystic, microcystic and combined forms of LM are known. The cysts are lined by lymphatic endothelial cells (LECs). Resection and sclerotherapy are the most common treatment methods.
Hannah Blesinger, Silke Kaulfuß, Thiha Aung, Sonja Schwoch, Lukas Prantl, Jochen Rößler, Jörg Wilting, Jürgen Becker   +7 more
openaire   +6 more sources

Polycystin Signaling Is Required for Directed Endothelial Cell Migration and Lymphatic Development

Cell Reports, 2014
Autosomal dominant polycystic kidney disease is a common form of inherited kidney disease that is caused by mutations in two genes, PKD1 (polycystin-1) and PKD2 (polycystin-2).
Patricia Outeda, David L. Huso, Steven A. Fisher, Marc K. Halushka, Hyunho Kim, Feng Qian, Gregory G. Germino, Terry Watnick   +7 more
doaj   +1 more source

Phomaketide A Inhibits Lymphangiogenesis in Human Lymphatic Endothelial Cells [PDF]

Marine Drugs, 2019
Lymphangiogenesis is an important biological process associated with cancer metastasis. The development of new drugs that block lymphangiogenesis represents a promising therapeutic strategy. Marine fungus-derived compound phomaketide A, isolated from the fermented broth of Phoma sp.
Huai-Ching Tai, Tzong-Huei Lee, Chih-Hsin Tang, Lei-Po Chen, Wei-Cheng Chen, Ming-Shian Lee, Pei-Chi Chen, Chih-Yang Lin, Chih-Wen Chi, Yu-Jen Chen, Cheng-Ta Lai, Shiou-Sheng Chen, Kuang-Wen Liao, Chien-Hsing Lee, Shih-Wei Wang   +14 more
openaire   +3 more sources