Brugia malayi Asparaginyl-tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis. [PDF]
PLoS ONE, 2016 A hallmark of chronic infection with lymphatic filarial parasites is the development of lymphatic disease which often results in permanent vasodilation and lymphedema, but all of the mechanisms by which filarial parasites induce pathology are not known ...
Jeeva Jothi D +5 more
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Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. [PDF]
, 2018 Arteries and veins are formed independently by different types of endothelial cells (ECs). In vascular remodeling, arteries and veins become connected and some arteries become veins. It is unclear how ECs in transforming vessels change their type and how
Ablooglu, Ararat J +6 more
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Neoplasia: An International Journal for Oncology Research, 2010 The lymphatic system plays a critical role in melanoma metastasis, and yet, virtually no information exists regarding the cellular and molecular mechanisms that take place between melanoma cells and the lymphatic vasculature.
Robert B. Rebhun +5 more
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Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration
Cell Reports, 2020 Summary: Regulatory T cells (Tregs) express high levels of cell surface lymphotoxin alpha beta (LTα1β2) to activate the LT beta receptor (LTβR) on the lymphatic endothelial cells (LECs), modulating LEC adhesion molecules, intercellular junctions, and ...
Wenji Piao +10 more
doaj +1 more source
Network development in biological gels: role in lymphatic vessel development [PDF]
, 2008 In this paper, we present a model that explains the prepatterning of lymphatic vessel morphology in collagen gels. This model is derived using the theory of two phase rubber material due to Flory and coworkers and it consists of two coupled fourth order ...
Fowler, A. C., Roose, Tiina
core +3 more sources
Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]
, 2010 Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F. +8 more
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Frontiers in Physiology, 2022 In recent years, the function of the lymphatic system in atherosclerosis has attracted attention due to its role in immune cell trafficking, cholesterol removal from the periphery, and regulation of the inflammatory response.
Shi-Ran Yu +6 more
doaj +1 more source
Microarray analyses demonstrate the involvement of type i interferons in psoriasiform pathology development in D6-deficient mice [PDF]
, 2013 The inflammatory response is normally limited by mechanisms regulating its resolution. In the absence of resolution, inflammatory pathologies can emerge, resulting in substantial morbidity and mortality.
Baldwin, H.M. +9 more
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Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]
, 2015 INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
AE Koch +33 more
core +2 more sources
Basal cell carcinoma stroma as a mimicker of lymphatic invasion: A case report
SAGE Open Medical Case Reports, 2020 Basal cell carcinoma metastases are rare. We report a case of an 83 year-old male with recurrent cutaneous infiltrative basal cell carcinoma on the right vertex with tumor aggregates of infiltrative basal cell carcinoma in the lymphatic vessels of the ...
Marco Caruana +3 more
doaj +1 more source