Results 31 to 40 of about 107,605 (342)
The lymphatic network of mammalian heart is an important regulator of interstitial fluid compartment and immune cell trafficking. We observed a remodeling of the cardiac lymphatic vessels and a reduced lymphatic efficiency during heart hypertrophy and ...
Mathilde Bizou +12 more
doaj +1 more source
TGF-β signaling in lymphatic vascular vessel formation and maintenance
Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
doaj +1 more source
FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature. [PDF]
Biomechanical forces, such as fluid shear stress, govern multiple aspects of endothelial cell biology. In blood vessels, disturbed flow is associated with vascular diseases, such as atherosclerosis, and promotes endothelial cell proliferation and ...
Amélie Sabine +26 more
core +4 more sources
Heterogeneity and Plasticity of Lymphatic Endothelial Cells [PDF]
Endothelial cells are found in most organs and tissues in our body. Despite their apparent morphological and functional similarities, endothelial cells exhibit remarkable heterogeneity and plasticity. In a strict sense, no two endothelial cells are identical in terms of their biological, immunological, functional, metabolic, morphological, and ...
Sunju, Lee, Inho, Choi, Young-Kwon, Hong
openaire +2 more sources
Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau +6 more
doaj +1 more source
Engineering Blood and Lymphatic Microvascular Networks in Fibrin Matrices [PDF]
Vascular network engineering is essential for nutrient delivery to tissue-engineered constructs and, consequently, their survival. In addition, the functionality of tissues also depends on tissue drainage and immune cell accessibility, which are the main
Hasenberg, Tobias +8 more
core +1 more source
Metabolic Analysis of Lymphatic Endothelial Cells [PDF]
Metabolism is pivotal for formation of the lymphatic vasculature. Understanding metabolism in lymphatic endothelial cells (LECs) requires quantitative characterization of specific metabolic pathways. Here we describe methods for using radioactive tracers to assess flux rates of glycolysis, fatty acid β-oxidation, glucose oxidation, and glutamine ...
Pengchun, Yu +3 more
openaire +2 more sources
Lymphatic Endothelial Differentiation in Pulmonary Lymphangioleiomyomatosis Cells [PDF]
Pulmonary lymphangioleiomyomatosis (LAM) is a rare, low-grade neoplasm affecting almost exclusively women of childbearing age. LAM belongs to the family of perivascular epithelioid cell tumors, characterized by spindle and epithelioid cells with smooth muscle and melanocytic differentiation.
Jennifer M, Davis +5 more
openaire +2 more sources
The intestinal lymphatic system: Functions and metabolic implications [PDF]
The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Cifarelli, Vincenza, Eichmann, Anne
core +2 more sources
Intestinal Lymphatic Endothelial Cells Produce R-Spondin3 [PDF]
AbstractThe R-Spondin (R-Spo) family regulates WNT signaling and stimulates the proliferation and differentiation of intestinal stem cells (ISCs). R-Spo plays a critical role in maintaining intestinal homeostasis, but endogenous producers of R-Spo in the intestine remain to be investigated.
Reiki Ogasawara +15 more
openaire +3 more sources

