Results 31 to 40 of about 107,605 (342)

Cardiac macrophage subsets differentially regulate lymphatic network remodeling during pressure overload

open access: yesScientific Reports, 2021
The lymphatic network of mammalian heart is an important regulator of interstitial fluid compartment and immune cell trafficking. We observed a remodeling of the cardiac lymphatic vessels and a reduced lymphatic efficiency during heart hypertrophy and ...
Mathilde Bizou   +12 more
doaj   +1 more source

TGF-β signaling in lymphatic vascular vessel formation and maintenance

open access: yesFrontiers in Physiology, 2022
Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
doaj   +1 more source

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature. [PDF]

open access: yes, 2015
Biomechanical forces, such as fluid shear stress, govern multiple aspects of endothelial cell biology. In blood vessels, disturbed flow is associated with vascular diseases, such as atherosclerosis, and promotes endothelial cell proliferation and ...
Amélie Sabine   +26 more
core   +4 more sources

Heterogeneity and Plasticity of Lymphatic Endothelial Cells [PDF]

open access: yesSeminars in Thrombosis and Hemostasis, 2010
Endothelial cells are found in most organs and tissues in our body. Despite their apparent morphological and functional similarities, endothelial cells exhibit remarkable heterogeneity and plasticity. In a strict sense, no two endothelial cells are identical in terms of their biological, immunological, functional, metabolic, morphological, and ...
Sunju, Lee, Inho, Choi, Young-Kwon, Hong
openaire   +2 more sources

Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation

open access: yesStem Cell Reports, 2019
Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau   +6 more
doaj   +1 more source

Engineering Blood and Lymphatic Microvascular Networks in Fibrin Matrices [PDF]

open access: yes, 2017
Vascular network engineering is essential for nutrient delivery to tissue-engineered constructs and, consequently, their survival. In addition, the functionality of tissues also depends on tissue drainage and immune cell accessibility, which are the main
Hasenberg, Tobias   +8 more
core   +1 more source

Metabolic Analysis of Lymphatic Endothelial Cells [PDF]

open access: yes, 2018
Metabolism is pivotal for formation of the lymphatic vasculature. Understanding metabolism in lymphatic endothelial cells (LECs) requires quantitative characterization of specific metabolic pathways. Here we describe methods for using radioactive tracers to assess flux rates of glycolysis, fatty acid β-oxidation, glucose oxidation, and glutamine ...
Pengchun, Yu   +3 more
openaire   +2 more sources

Lymphatic Endothelial Differentiation in Pulmonary Lymphangioleiomyomatosis Cells [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 2013
Pulmonary lymphangioleiomyomatosis (LAM) is a rare, low-grade neoplasm affecting almost exclusively women of childbearing age. LAM belongs to the family of perivascular epithelioid cell tumors, characterized by spindle and epithelioid cells with smooth muscle and melanocytic differentiation.
Jennifer M, Davis   +5 more
openaire   +2 more sources

The intestinal lymphatic system: Functions and metabolic implications [PDF]

open access: yes, 2019
The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Cifarelli, Vincenza, Eichmann, Anne
core   +2 more sources

Intestinal Lymphatic Endothelial Cells Produce R-Spondin3 [PDF]

open access: yesScientific Reports, 2018
AbstractThe R-Spondin (R-Spo) family regulates WNT signaling and stimulates the proliferation and differentiation of intestinal stem cells (ISCs). R-Spo plays a critical role in maintaining intestinal homeostasis, but endogenous producers of R-Spo in the intestine remain to be investigated.
Reiki Ogasawara   +15 more
openaire   +3 more sources

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