Results 31 to 40 of about 5,519,715 (191)

Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]

open access: yes, 2009
Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
core   +1 more source

Cardiac macrophage subsets differentially regulate lymphatic network remodeling during pressure overload

open access: yesScientific Reports, 2021
The lymphatic network of mammalian heart is an important regulator of interstitial fluid compartment and immune cell trafficking. We observed a remodeling of the cardiac lymphatic vessels and a reduced lymphatic efficiency during heart hypertrophy and ...
Mathilde Bizou   +12 more
doaj   +1 more source

TGF-β signaling in lymphatic vascular vessel formation and maintenance

open access: yesFrontiers in Physiology, 2022
Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
doaj   +1 more source

Metabolic Analysis of Lymphatic Endothelial Cells [PDF]

open access: yes, 2018
Metabolism is pivotal for formation of the lymphatic vasculature. Understanding metabolism in lymphatic endothelial cells (LECs) requires quantitative characterization of specific metabolic pathways. Here we describe methods for using radioactive tracers to assess flux rates of glycolysis, fatty acid β-oxidation, glucose oxidation, and glutamine ...
Pengchun, Yu   +3 more
openaire   +2 more sources

Lymphatic Endothelial Cell Plasticity in Development and Disease [PDF]

open access: yesPhysiology, 2017
The lymphatic vasculature is crucial for maintaining tissue-fluid homeostasis, providing immune surveillance and mediating lipid absorption. The lymphatic vasculature is tightly associated with the blood vasculature, although it exhibits distinct morphological and functional features.
Wanshu, Ma, Guillermo, Oliver
openaire   +2 more sources

Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]

open access: yes, 2011
The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine   +9 more
core   +2 more sources

Lymphatic Endothelial Differentiation in Pulmonary Lymphangioleiomyomatosis Cells [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 2013
Pulmonary lymphangioleiomyomatosis (LAM) is a rare, low-grade neoplasm affecting almost exclusively women of childbearing age. LAM belongs to the family of perivascular epithelioid cell tumors, characterized by spindle and epithelioid cells with smooth muscle and melanocytic differentiation. LAM cells infiltrate the lungs, producing multiple, bilateral
Jennifer M, Davis   +5 more
openaire   +2 more sources

Molecular Mechanisms Controlling Lymphatic Endothelial Junction Integrity

open access: yesFrontiers in Cell and Developmental Biology, 2021
The lymphatic system is essential for lipid absorption/transport from the digestive system, maintenance of tissue fluid and protein homeostasis, and immune surveillance.
Pieter R. Norden, Tsutomu Kume
doaj   +1 more source

Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins

open access: yesFrontiers in Cell and Developmental Biology, 2023
Background and purpose: Previous experimental studies have shown that meningeal lymphatic vessels are located primarily along the walls of the dural sinus veins.
César Luis Vera Quesada   +5 more
doaj   +1 more source

Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in mice.

open access: yesPLoS ONE, 2012
The coxsackie- and adenovirus receptor (CAR) is a cell adhesion molecule predominantly associated with epithelial tight junctions in adult tissues. CAR is also expressed in cardiomyocytes and essential for heart development up to embryonic day 11.5, but ...
Momina Mirza   +8 more
doaj   +1 more source

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