Results 21 to 30 of about 5,519,715 (191)

Role of Transcriptional and Epigenetic Regulation in Lymphatic Endothelial Cell Development. [PDF]

Cells, 2022
The lymphatic system is critical for maintaining the homeostasis of lipids and interstitial fluid and regulating the immune cell development and functions.
La H, Yoo H, Park YB, Thang NX, Park C, Yoo S, Lee H, Choi Y, Song H, Do JT, Hong K.   +10 more
europepmc   +2 more sources

Fine filaments in lymphatic endothelial cells [PDF]

The Journal of Cell Biology, 1976
Several and various types of cells contain fine cytoplasmic filaments closely resembling the myofilaments of muscle cells (2, 18, 23, 24). In many of these cells and especially when cultured, it has been demonstrated that some of these filaments react with heavy meromyosin (HMM) in the same way as do the actin filaments of muscle cells (3, 6 7).
J M, Lauweryns, J, Baert, W, De Loecker
openaire   +2 more sources

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity. [PDF]

Elife, 2020
Endothelial integrity is vital for homeostasis and adjusted to tissue demands. Although fluid uptake by lymphatic capillaries is a critical attribute of the lymphatic vasculature, the barrier function of collecting lymphatic vessels is also important by ...
Frye M, Stritt S, Ortsäter H, Hernandez Vasquez M, Kaakinen M, Vicente A, Wiseman J, Eklund L, Martínez-Torrecuadrada JL, Vestweber D, Mäkinen T.   +10 more
europepmc   +2 more sources

Lymphatic Endothelial Cell Progenitors in the Tumor Microenvironment. [PDF]

Adv Exp Med Biol, 2020
Tumor lymphatics play a key role in cancer progression as they are solely responsible for transporting malignant cells to regional lymph nodes (LNs), a process that precedes and promotes systemic lethal spread. It is broadly accepted that tumor lymphatic sprouting is induced mainly by soluble factors derived from tumor-associated macrophages (TAMs) and
Ran S, Volk-Draper L.
europepmc   +4 more sources

Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell [PDF]

Development, 2010
Lineage commitment and differentiation into mature cell types are mostly considered to be unidirectional and irreversible processes. However, recent results have challenged this by showing that terminally differentiated cell types can be reprogrammed into other cell types, an important step towards devising strategies for gene therapy and tissue ...
Guillermo, Oliver, R Sathish, Srinivasan
openaire   +2 more sources

Regulation of T-cell Tolerance by Lymphatic Endothelial Cells [PDF]

Journal of Clinical & Cellular Immunology, 2014
Lymphatic endothelial cells are most often thought of as structural cells that form the lymphatic vasculature, which transports fluid out of peripheral tissues and transports antigens and antigen presenting cells to lymph nodes. Recently, it has been shown that lymphatic endothelial cells also dynamically respond to and influence the immune response in
Rouhani, Sherin J., Eccles, Jacob D., Tewalt, Eric F., Engelhard, Victor H.   +3 more
openaire   +2 more sources

A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development [PDF]

, 2010
The molecular mechanisms that regulate the earliest steps of lymphatic vascular system development are unknown. To identify regulators of lymphatic competence and commitment, we used an in vitro vascular assay with mouse embryonic stem cell-derived ...
Dabouras, Vasilios, Marino, Daniela, Vasilios Dabouras, Detmar, Michael, Braendli, Andre W., Michael Detmar, André W. Brändli, Daniela Marino, Brändli AW, Marino D, Dabouras V, Detmar M   +11 more
core   +1 more source

Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]

, 2010
Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren, Koh, Chester J., Aguilar Berenice, Yoo, Jaehyuk, Hong Young-Kwon, Hong, Young-Kwon, Lee, Sunju, Choi, Inho, Yoo Jaehyuk, Haas, Jürgen G., Kang Jinjoo, Lee Ha Neul, Swapnika Ramu, Kang, Jinjoo, Young-Kwon Hong, Juneyong Lee, Ramu, Swapnika, Darren Kafka, Lee, Juneyong, Kafka Darren, Lee Sunju, Choi Inho, Juergen Haas, Haas, Juergen, Lee Juneyong, Sunju Lee, Inho Choi, Ha Neul Lee, Haas Juergen, Aguilar, Berenice, Chester J. Koh, Jinjoo Kang, Chester J Koh, Jaehyuk Yoo, Koh Chester J., Berenice Aguilar, Ramu Swapnika, Lee, Ha Neul   +37 more
core   +1 more source

FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake

Molecular Medicine, 2020
Background Therapeutic lymphangiogenesis in an orthotopic lung transplant model has been shown to improve acute allograft rejection that is mediated at least in part through hyaluronan drainage.
Shikshya Shrestha, Woohyun Cho, Benjamin Stump, Jewel Imani, Anthony M. Lamattina, Pierce H. Louis, James Pazzanese, Ivan O. Rosas, Gary Visner, Mark A. Perrella, Souheil El-Chemaly   +10 more
doaj   +1 more source

Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium [PDF]

, 2010
The lymphatic vascular system plays an important role in inflammation and cancer progression, although the molecular mechanisms involved are poorly understood.
Proulx, Steven T, Iolyeva, Maria, Steven T. Proulx, Cornelia Halin, Giorgia Jurisic, Detmar, Michael, Michael Detmar, Maria Iolyeva, Jurisic, Giorgia, Halin, Cornelia, Proulx ST, Iolyeva M, Halin C, Jurisic G, Detmar M   +14 more
core   +2 more sources