Results 41 to 50 of about 107,605 (342)

Molecular Mechanisms Controlling Lymphatic Endothelial Junction Integrity

open access: yesFrontiers in Cell and Developmental Biology, 2021
The lymphatic system is essential for lipid absorption/transport from the digestive system, maintenance of tissue fluid and protein homeostasis, and immune surveillance.
Pieter R. Norden, Tsutomu Kume
doaj   +1 more source

Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell [PDF]

open access: yesDevelopment, 2010
Lineage commitment and differentiation into mature cell types are mostly considered to be unidirectional and irreversible processes. However, recent results have challenged this by showing that terminally differentiated cell types can be reprogrammed into other cell types, an important step towards devising strategies for gene therapy and tissue ...
Guillermo, Oliver, R Sathish, Srinivasan
openaire   +2 more sources

Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins

open access: yesFrontiers in Cell and Developmental Biology, 2023
Background and purpose: Previous experimental studies have shown that meningeal lymphatic vessels are located primarily along the walls of the dural sinus veins.
César Luis Vera Quesada   +5 more
doaj   +1 more source

Regulation of T-cell Tolerance by Lymphatic Endothelial Cells [PDF]

open access: yesJournal of Clinical & Cellular Immunology, 2014
Lymphatic endothelial cells are most often thought of as structural cells that form the lymphatic vasculature, which transports fluid out of peripheral tissues and transports antigens and antigen presenting cells to lymph nodes. Recently, it has been shown that lymphatic endothelial cells also dynamically respond to and influence the immune response in
Rouhani, Sherin J.   +3 more
openaire   +2 more sources

A robust in vitro model for trans-lymphatic endothelial migration

open access: yesScientific Reports, 2017
Trans-endothelial migration (TEM) is essential for leukocyte circulation. While much is known about trans-blood endothelial migration, far less is known about trans-lymphatic endothelial migration.
Yanbao Xiong   +7 more
doaj   +1 more source

Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia

open access: yesCell Reports, 2017
Summary: Trafficking cells frequently transmigrate through epithelial and endothelial monolayers. How monolayers cooperate with the penetrating cells to support their transit is poorly understood.
Kari Vaahtomeri   +7 more
doaj   +1 more source

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

open access: yes, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker   +16 more
core   +2 more sources

Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment. [PDF]

open access: yesPLoS ONE, 2014
Peripheral self-tolerance eliminates lymphocytes specific for tissue-specific antigens not encountered in the thymus. Recently, we demonstrated that lymphatic endothelial cells in mice directly express peripheral tissue antigens, including tyrosinase ...
Jarish N Cohen   +8 more
doaj   +1 more source

Antigen-presenting cells and antigen presentation in tertiary lymphoid organs [PDF]

open access: yes, 2016
Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures.
Bedaj, Marija   +3 more
core   +1 more source

Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges

open access: yesCells, 2021
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj   +1 more source

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