Results 11 to 20 of about 5,519,715 (191)
Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges [PDF]
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj +4 more sources
A robust in vitro model for trans-lymphatic endothelial migration
Trans-endothelial migration (TEM) is essential for leukocyte circulation. While much is known about trans-blood endothelial migration, far less is known about trans-lymphatic endothelial migration.
Yanbao Xiong +7 more
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Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia [PDF]
Summary: Trafficking cells frequently transmigrate through epithelial and endothelial monolayers. How monolayers cooperate with the penetrating cells to support their transit is poorly understood.
Kari Vaahtomeri +7 more
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Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau +6 more
doaj +2 more sources
Recent advances in developmental biology and single-cell transcriptomics have revealed remarkable endothelial heterogeneity within the central nervous system, leading to the identification of specialized endothelial populations at brain border regions ...
Junxiang Xu +4 more
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Mechanisms of Lymphatic Endothelial Cell Junction Transformations. [PDF]
Zhong J, Shelton EL, Kirabo A, Kon V.
europepmc +3 more sources
Detection, Isolation and Culture of Lymphatic Endothelial Cells
Lymphatic vessels are essential for the maintenance of normal tissue fluid balance and immune surveillance, but they also provide a pathway for metastasis in many types of cancers (reviewed in Alitalo and Carmeliet 2002). In spite of the importance of lymphatic vessels in medicine, the cell biology of this part of the vascular system has received ...
Mäkinen, T., Alitalo, K.
openaire +3 more sources
A short review on lymphatic endothelial cell heterogeneity. [PDF]
AbstractRecent single-cell RNA sequencing studies in mouse and human have clearly indicated that lymphatic endothelial cells (LECs) consist of multiple cell subsets, each expressing a unique set of genes, residing in distinct locations in the body. These studies have also revealed a conserved pattern of gene expression in LECs across animal species, as
Miyasaka M.
europepmc +4 more sources
Molecular characterization of lymphatic endothelial cells [PDF]
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins and is an important entry point for leukocytes and tumor cells. Specialized functions of lymphatics suggest differences in the molecular composition of the lymphatic and blood vascular endothelium.
Simona Podgrabinska +6 more
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Lymphangiogenesis, formation of lymphatic vessels from pre-existing vessels, is a dynamic process that requires cell migration. Regardless of location, migrating lymphatic endothelial cell (LEC) progenitors probe their surroundings to form the lymphatic ...
Allalou, Amin +32 more
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