Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity [PDF]
Journal of Experimental Medicine, 2021 Lymphatic endothelial cells (LECs) present peripheral tissue antigens to induce T cell tolerance. In addition, LECs are the main source of sphingosine-1-phosphate (S1P), promoting naive T cell survival and effector T cell exit from lymph nodes (LNs). Autophagy is a physiological process essential for cellular homeostasis.
Guillaume Harlé +10 more
exaly +8 more sources
A short review on lymphatic endothelial cell heterogeneity. [PDF]
Inflamm Regen, 2021 AbstractRecent single-cell RNA sequencing studies in mouse and human have clearly indicated that lymphatic endothelial cells (LECs) consist of multiple cell subsets, each expressing a unique set of genes, residing in distinct locations in the body. These studies have also revealed a conserved pattern of gene expression in LECs across animal species, as
Miyasaka M.
europepmc +6 more sources
Hypoxia Increases Breast Cancer Cell-Induced Lymphatic Endothelial Cell Migration
Neoplasia, 2008 Because tumors are characterized by hypoxic environments, we used a novel in vitro noninvasive magnetic resonance imaging assay to examine the influence of invasive MDA-MB-231 breast cancer cells on the invasion and migration of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) under normoxic and hypoxic conditions.
Maria Mikhaylova +5 more
openalex +4 more sources
Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells [PDF]
Frontiers in Immunology, 2019 Liver lymphatic vessels support liver function by draining interstitial fluid, cholesterol, fat, and immune cells for surveillance in the liver draining lymph node.
Beth A. Jiron Tamburini +13 more
doaj +2 more sources
How Lymphatic Endothelial Cells Destabilize Regulatory T Cells [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2022 Qingkang Lyu, Klaus Ley
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Mechanisms of Lymphatic Endothelial Cell Junction Transformations. [PDF]
Circ Res, 2023 Zhong J, Shelton EL, Kirabo A, Kon V.
europepmc +3 more sources
Lymphangioleiomyoma Cells and Lymphatic Endothelial Cells [PDF]
The American Journal of Pathology, 2010 Kuniaki Seyama +7 more
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Transcriptomic and Functional Evidence That miRNA193a-3p Inhibits Lymphatic Endothelial Cell (LEC) and LEC + MCF-7 Spheroid Growth Directly and by Altering MCF-7 Secretome. [PDF]
Cells, 2023 Azzarito G +4 more
europepmc +3 more sources
Myeloid Derived Suppressor Cells Migrate in Response to Flow and Lymphatic Endothelial Cell Interaction in the Breast Tumor Microenvironment. [PDF]
Cancers (Basel), 2022 Roberts LM +5 more
europepmc +3 more sources
Fine filaments in lymphatic endothelial cells [PDF]
The Journal of Cell Biology, 1976 Several and various types of cells contain fine cytoplasmic filaments closely resembling the myofilaments of muscle cells (2, 18, 23, 24). In many of these cells and especially when cultured, it has been demonstrated that some of these filaments react with heavy meromyosin (HMM) in the same way as do the actin filaments of muscle cells (3, 6 7).
J M, Lauweryns, J, Baert, W, De Loecker
openaire +2 more sources