Results 11 to 20 of about 5,519,715 (191)

Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges [PDF]

open access: yesCells, 2021
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj   +4 more sources

A robust in vitro model for trans-lymphatic endothelial migration

open access: yesScientific Reports, 2017
Trans-endothelial migration (TEM) is essential for leukocyte circulation. While much is known about trans-blood endothelial migration, far less is known about trans-lymphatic endothelial migration.
Yanbao Xiong   +7 more
doaj   +2 more sources

Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia [PDF]

open access: yesCell Reports, 2017
Summary: Trafficking cells frequently transmigrate through epithelial and endothelial monolayers. How monolayers cooperate with the penetrating cells to support their transit is poorly understood.
Kari Vaahtomeri   +7 more
doaj   +2 more sources

Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation

open access: yesStem Cell Reports, 2019
Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau   +6 more
doaj   +2 more sources

Mural Lymphatic Endothelial Cells at CNS Borders: Endothelial Heterogeneity, Functional Specialization, and Cross-Species Perspectives

open access: yesBiology
Recent advances in developmental biology and single-cell transcriptomics have revealed remarkable endothelial heterogeneity within the central nervous system, leading to the identification of specialized endothelial populations at brain border regions ...
Junxiang Xu   +4 more
doaj   +2 more sources

Detection, Isolation and Culture of Lymphatic Endothelial Cells

open access: yes, 2004
Lymphatic vessels are essential for the maintenance of normal tissue fluid balance and immune surveillance, but they also provide a pathway for metastasis in many types of cancers (reviewed in Alitalo and Carmeliet 2002). In spite of the importance of lymphatic vessels in medicine, the cell biology of this part of the vascular system has received ...
Mäkinen, T., Alitalo, K.
openaire   +3 more sources

A short review on lymphatic endothelial cell heterogeneity. [PDF]

open access: yesInflamm Regen, 2021
AbstractRecent single-cell RNA sequencing studies in mouse and human have clearly indicated that lymphatic endothelial cells (LECs) consist of multiple cell subsets, each expressing a unique set of genes, residing in distinct locations in the body. These studies have also revealed a conserved pattern of gene expression in LECs across animal species, as
Miyasaka M.
europepmc   +4 more sources

Molecular characterization of lymphatic endothelial cells [PDF]

open access: yesProceedings of the National Academy of Sciences, 2002
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins and is an important entry point for leukocytes and tumor cells. Specialized functions of lymphatics suggest differences in the molecular composition of the lymphatic and blood vascular endothelium.
Simona Podgrabinska   +6 more
openaire   +2 more sources

mafba and mafbb differentially regulate lymphatic endothelial cell migration in topographically distinct manners

open access: yes, 2022
Lymphangiogenesis, formation of lymphatic vessels from pre-existing vessels, is a dynamic process that requires cell migration. Regardless of location, migrating lymphatic endothelial cell (LEC) progenitors probe their surroundings to form the lymphatic ...
Allalou, Amin   +32 more
core   +2 more sources

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