Results 161 to 170 of about 23,592 (245)

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

Klippel‐Trénaunay‐Weber Syndrome: Prenatal Diagnosis and Review of the Literature

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 535-546, March/April 2025.
This meta‐analysis demonstrates the high diagnostic accuracy of SZ‐CEUS for differentiating between malignant and benign focal liver lesions, as well as for HCC from non‐HCC lesions. The study shows better performance for smaller lesions and those with a higher proportion of malignancy.
Giuliana Orlandi, Laura Sarno, Antonio Angelino, Mariarosaria Motta, Raffaella Di Girolamo, Luigi Carbone, Marika Rovetto, Laura Letizia Mazzarelli, Gabriella Sglavo, Francesco D' Antonio, Ilenia Mappa, Daniele Di Mascio, Giuseppe Rizzo, Giuseppe Maria Maruotti   +13 more
wiley   +1 more source

From Negative Duplex to Phlegmasia in Minutes: Bedside POCUS Identifies Rapid Thrombosis Unmasking Underlying May–Thurner Syndrome

Journal of Clinical Ultrasound, EarlyView.
Point‐of‐care‐ultrasound revealed an evolving acute noncompressible deep vein thrombosis (asterisks) in the left lower extremity veins (right panel) that was not evident on duplex ultrasound 14 min prior (left panel; asterisks demonstrate compressed veins). The patient was treated emergently and found to have May–Thurner syndrome.
Anthony Unger
wiley   +1 more source

Angiosarcoma of the Scalp Presenting With Eyelid Edema: A Diagnostic Pitfall of Eyelid Biopsy

JEADV Clinical Practice, EarlyView.
ABSTRACT Angiosarcoma of the scalp is a rare but aggressive vascular malignancy that may present with nonspecific clinical findings, potentially leading to delayed diagnosis. Eyelid edema is an uncommon initial manifestation and has been suggested to result from direct tumor infiltration or lymphatic obstruction.
Sayo Komiyama, Sayaka Yamaguchi, Akiko Kaneshima, Aya Sunagawa, Shuhei Yonamine, Takuya Miyagi, Teruki Yanagi, Kenzo Takahashi   +7 more
wiley   +1 more source

Active endothelial and neural regulation of valve biology, health, and disease. [PDF]

Front Cardiovasc Med
Janani G, Nguyen KL, Butcher JT.
europepmc   +1 more source

Construction of a Non‐Invasive Predictive Model Based on PIVKA‐II Combined With MRI Imaging Features for Evaluating Microvascular Invasion in Hepatocellular Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
wiley   +1 more source

KAT2A Promotes the Progression of Renal Cell Carcinoma by Regulating the Succinylation of SERPINE2

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) and angiogenesis are critical drivers of renal cell carcinoma (RCC) progression, yet their upstream regulatory mechanisms remain incompletely understood. This study aimed to investigate the role of KAT2A in RCC and elucidate the underlying molecular mechanism by which it promotes tumor progression.
Chang‐Cheng Liu, Xue‐Dong Li
wiley   +1 more source

Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium. [PDF]

J Biol Chem, 2016
Banerji S, Lawrance W, Metcalfe C, Briggs DC, Yamauchi A, Dushek O, van der Merwe PA, Day AJ, Jackson DG.   +8 more
europepmc   +1 more source

Development and External Validation of a Postoperative Risk Score for Venous Thromboembolism in Epithelial Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui, Yu‐Shi He, Xuan‐Hui Wang, Cheng Li, Gang Wang, Ming Chen, Shu‐Min Chen   +6 more
wiley   +1 more source