Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium. [PDF]
Endothelial cells (ECs), which line blood and lymphatic vessels, are generally described to come from the lateral plate mesoderm despite experimental evidence for a broader source of origin, including the paraxial mesoderm (PXM). Current dogma suggests that following specification from mesoderm, local environmental cues establish the distinct molecular
Stone OA, Stainier DYR.
europepmc +7 more sources
Emerging roles of lymphatic endothelium in regulating adaptive immunity. [PDF]
Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). LECs are presumably the first cells that come into direct contact with peripheral antigens, cytokines, danger signals, and immune cells travelling from peripheral tissues to lymph nodes.
Card CM, Yu SS, Swartz MA.
europepmc +5 more sources
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged.
Michael S. Pepper, Mihaela Skobe
+5 more sources
Tumour cells express functional lymphatic endothelium-specific hyaluronan receptor in vitro and in vivo: Lymphatic mimicry promotes oral oncogenesis? [PDF]
Karinen S +9 more
europepmc +3 more sources
mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn’s Disease [PDF]
Crohn’s disease (CD) is a chronic inflammatory condition that can affect different portions of the gastrointestinal tract. Lymphatic drainage was demonstrated to be dysfunctional in CD pathogenesis, ultimately causing the failure of the resolution ...
Federica Ungaro +13 more
doaj +2 more sources
Direct specification of lymphatic endothelium from non-venous angioblasts [PDF]
Lupu I +10 more
europepmc +2 more sources
Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. [PDF]
Engelbrecht E +15 more
europepmc +2 more sources
Role of lymphatic endothelium specific hyaluronan receptor 1 in virus infection and associated diseases. [PDF]
Dai L, Qin Z.
europepmc +3 more sources
Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium. [PDF]
Kedl RM, Tamburini BA.
europepmc +3 more sources
AP-1 Is an Initial Convergent Transcriptional Response in Lymphatic Endothelium to VEGF-C or TNFα. [PDF]
Kreft EA, Juśkiewicz ZJ, Isakson BE.
europepmc +3 more sources

