Results 191 to 200 of about 271,816 (268)

Mechanical Stretch‐Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin

Advanced Science, EarlyView.
Regeneration reaches a hidden limit under mechanical stretch. Prolonged tension alters dermal–epidermal communication, exhausting epidermal stem cells via MMP2–COL17A1 signaling. MMP2 inhibition by Marimastat preserves adhesion and regenerative capacity, offering a potential strategy to overcome the inherent boundaries of skin expansion.
Yidan Sun, Qili Qian, Luwen Xu, Bowen Gao, Ting Li, Yin Li, Jiayi Zheng, Qiaoyu Fu, Xi Cheng, Nuo Chen, Sijia Wang, Liang Zhang, Caiyue Liu, Qingfeng Li   +13 more
wiley   +1 more source

Mannose Receptor Is a Novel Ligand for L-Selectin and Mediates Lymphocyte Binding to Lymphatic Endothelium [PDF]

, 2001
Heikki Irjala, Eva-Liz Johansson, Reidar Grénman, Kalle Alanen, Marko Salmi, Sirpa Jalkanen   +5 more
openalex   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

ATP-induced endothelium-independent enhancement of lymphatic vasomotion in guinea-pig mesentery involves P_2Xand P_2Yreceptors [PDF]

, 2002
Jun Zhao, Dirk van Helden
openalex   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source

Monoclonal Antibody D2-40, a New Marker of Lymphatic Endothelium, Reacts with Kaposi's Sarcoma and a Subset of Angiosarcomas [PDF]

, 2002
Harriette J. Kahn, Denis Bailey, Alexander Marks   +2 more
openalex   +1 more source

[Lymphatic endothelium].

Postepy biochemii, 2014
Compared to the knowledge about the structure and function of endothelial cells of blood vessels, which was heavily developed over the past few decades, advance in the knowledge of lymphatic endothelial cells (LECs) for many years has been impossible, because of the lack of specific methods that allow histological visualization of lymphatic vessels in ...
Angelika, Chachaj, Andrzej, Szuba
openaire   +1 more source

NO‐Driven Janus Nanomotor Enhances T‐Cell Infiltration by Reconstructing Tumor‐Associated Blood and Lymphatic Vessels

Advanced Science, EarlyView.
NO‐driven hollow gold Janus nanomotors (HAM) are engineered to improve tumor blood vessel normalization throughout the entire tumor region to enhance T‐cell intratumoral infiltration, and generate and capture whole‐tumor antigens as an in situ cancer vaccine to enhance T‐cell activation, therefore enhancing the antitumor immune response.
Qingping Ma, Shunli Fu, Yiming Xia, Shuying Gao, Zhenxing Xia, Panpan Gu, Shijun Yuan, Jinhu Liu, Shuang Liang, Nan Li, Qinglin Yang, Weiwei Mu, Jie Liu, Xinrui Liu, Yongjun Liu, Na Zhang   +15 more
wiley   +1 more source

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

Proceedings of the National Academy of Sciences of the United States of America, 1995
A. Kaipainen, J. Korhonen, T. Mustonen, V. Hinsbergh, G. Fang, D. Dumont, M. Breitman, K. Alitalo   +7 more
semanticscholar   +1 more source

Author response: Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation

, 2018
Pirita Pekkonen, Sanni Alve, Giuseppe Balistreri, Silvia Gramolelli, Olga Tatti-Bugaeva, Ilkka Paatero, Otso Niiranen, Krista Tuohinto, Nina Perälä, Adewale Taiwo, Nadezhda Zinovkina, Pauliina Repo, Katherine Icay, Johanna Ivaska, Pipsa Saharinen, Sampsa Hautaniemi, Kaisa Lehti, Päivi M. Ojala   +17 more
openalex   +1 more source