Results 71 to 80 of about 128,807 (261)

Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation [PDF]

, 2020
Lymphatic malformations (LMs) are debilitating vascular anomalies presenting with large cysts (macrocystic) or lesions that infiltrate tissues (microcystic). Cellular mechanisms underlying LM pathology are poorly understood. Here we show that the somatic
Graupera, Mariona,, Martinez-Corral, Ines,, Castillo, Sandra D.,, Saur, Dieter, Vikkula, Miikka, Pascal Brouillard, Alitalo, Kari, Sandra D. Castillo, Taija Mäkinen, Vikkula, Miikka,, Mäkinen, Taija,, Martínez Corral, Inés, Brouillard, Pascal,, Boon, Laurence,, Ortsäter, Henrik, Martinez-Corral, Ines, Boon, Laurence, Petkova, Milena, Libbrecht, Louis, Castillo, Sandra D., Sofie Sjöberg, Alitalo, Kari,, Mariona Graupera, Zhang, Yan, Castillo, Sandra D, Boon, Laurence M., Mäkinen, Taija, Henrik Ortsäter, Dieter Saur, Ortsäter, Henrik,, Kari Alitalo, Petkova, Milena,, Saur, Dieter,, Graupera, Mariona, Louis Libbrecht, Miikka Vikkula, Graupera i Garcia-Milà, Mariona, Sjöberg, Sofie, Sjöberg, Sofie,, Milena Petkova, Zhang, Yan,, Yan Zhang, Ines Martinez-Corral, Laurence Boon, Brouillard, Pascal, Libbrecht, Louis,   +45 more
core   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Orbital venous-lymphatic malformations (lymphangiomas) mimicking cavernous hemangiomas.

, 2001
PURPOSE: To illustrate that orbital venous-lymphatic malformations (lymphangiomas) may rarely simulate cavernous hemangiomas, METHODS: Retrospective case review.
SELVA D, BONAVOLONTA G, ROOTMAN J., STRIANESE, DIEGO, Dinesh Selva, Diego Strianese, Jack Rootman, Giulio Bonavolonta   +7 more
core   +1 more source

Reln mRNA Delivery Drives Neurogenic Bone Regeneration by Orchestrating Schwann Cell‐Mediated Exosomal Trafficking

Advanced Science, EarlyView.
MSNs serve as a robust vehicle for CRISPRa‐mediated Reln induction, driving bone repair through the establishment of a neurogenic‐supportive microenvironment. ABSTRACT Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, while the mechanisms and new strategies underlying neurogenic bone regeneration ...
Shuai Lin, Qianwen Li, Duo Liu, Mingzhao Li, Han Zhang, Liujing Chen, Yan Yu, Jiuhui Jiang, Chun Xu, Ruili Yang   +9 more
wiley   +1 more source

Sclerotherapy in Lymphatic Malformations with Intralesional Hemorrhage: A Retrospective Comparison with Non-Hemorrhagic Lymphatic Malformations

Clinical, Cosmetic and Investigational Dermatology, 2022
Wenjing Wang,1 Boce Liu,1 Junsong Long,1 Jianhai Bi,2 Ran Huo1,2 1Department of Plastic Surgery, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, People’s Republic of China; 2Department of Plastic Surgery, Shandong Provincial Hospital ...
Wang W, Liu B, Long J, Bi J, Huo R
doaj  

Are we nearly there yet? Coverage and compliance of mass drug administration for lymphatic filariasis elimination. [PDF]

, 2015
Lymphatic filariasis has been targeted for elimination by 2020, and a threshold of 65% coverage of mass drug administration (MDA) has been adopted by the Global Programme to Eliminate Lymphatic Filariasis (GPELF).
Alexander, Neal DE
core   +1 more source

High Diagnosis Rate for Nonimmune Hydrops Fetalis With Prenatal Clinical Genome: Expanded Results From the Hydrops‐Yielding Diagnostic Results of Prenatal Sequencing (HYDROPS) Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nonimmune hydrops fetalis (NIHF) is characterized by abnormal fluid accumulation in ≥ 2 fetal compartments and may be genetic. The incremental diagnostic yield of prenatal exome sequencing (ES) for NIHF following a negative standard workup was previously explored on 22 cases.
Stephanie M. Rice, Mona M. Makhamreh, Sascha Wodoslawsky, Mariella Toro, Elizabeth Critchlow, Brandy Firman, Ruby Liu, Babi Ramesh Nallamilli, Madhuri Hegde, Seth I. Berger, Huda B. Al‐Kouatly   +10 more
wiley   +1 more source

Spontaneously Resolved Macrocystic Lymphatic Malformations: Predictive Variables and Outcomes

, 2017
Introduction: Lymphatic malformations are benign, low-flow vascular malformations that typically present at or near birth. Due to morbidity associated with operative treatment, nonoperative treatment with injection of sclerosant has become the mainstay ...
Michael J. Phang, Marija Bucevska, Claudia Malic, Douglas J. Courtemanche, Jugpal S. Arneja   +4 more
core   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source

Lymphatic malformation of the masseter: A case report

Journal of Oral Biology and Craniofacial Research, 2018
Intramuscular vascular malformations are rare tumours occurring in less than 1% of skeletal muscles throughout the body, about 15% arising in the head and neck.
Sanjay Kumar, Padmanidhi Agarwal, Divya Mehrotra, Nimmi Vijayan   +3 more
doaj   +1 more source