Results 61 to 70 of about 128,807 (261)

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

open access: yesAdvanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma   +12 more
wiley   +1 more source

Lymphatic malformations: a proposed management algorithm.

open access: yes, 2012
OBJECTIVE: The aim of this study was to develop a management algorithm for cervicofacial lymphatic malformations, based on the authors' experience in managing these lesions as well as current literature on the subject.
Oosthuizen, J C, Burns, P, Russell, J D
core   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

open access: yesAdvanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty   +4 more
wiley   +1 more source

Aggressive giant cystic lymphatic malformation in a newborn

open access: yesThe Turkish Journal of Pediatrics, 2013
Lymphatic malformations are uncommon, benign and congenital malformations of the lymphatic system exhibiting lack of development of communication between the lymphatic and venous circulation.
Mert Calış   +4 more
doaj  

Genetic tests in lymphatic vascular malformations and lymphedema.

open access: yes, 2018
Syndromes with lymphatic malformations show phenotypic variability within the same entity, clinical features that overlap between different conditions and allelic as well as locus heterogeneity.
Paolacci, Stefano   +13 more
core   +1 more source

PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations. [PDF]

open access: yes, 2018
Lymphatic malformations (LM) are characterized by the overgrowth of lymphatic vessels during pre- and postnatal development. Macrocystic, microcystic and combined forms of LM are known. The cysts are lined by lymphatic endothelial cells (LECs). Resection
Jürgen Becker   +17 more
core   +2 more sources

Magnetic Thermal Ablation Combined with Temporally Coordinated CpG Immunotherapy Promotes cDC1‐Dependent Immune Priming in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Novel PLA@Fe3O4 magnetic microspheres were developed for transarterial magnetic hyperthermia ablation (MTA) of hepatocellular carcinoma. While destroying local tumors and inducing immunogenic cell death (ICD), MTA combined with early CpG adjuvant administration significantly promotes cDC1‐dependent immune priming. This synergistic mechanism effectively
Jiakun Yang   +8 more
wiley   +1 more source

A case of huge lymphatic and venous malformations of the mediastinum

open access: yesRespiratory Medicine Case Reports, 2019
We herein report a case of huge lymphatic and venous malformations of the mediastinum (LVM). A 19-year-old man presented for evaluation of a mediastinal mass.
Miyuki Munechika   +7 more
doaj   +1 more source

Chyluria: non-enhanced MR lymphography

open access: yesInsights into Imaging, 2023
Chyluria is an uncommon medical condition resulting from an abnormal communication between the abdominal lymphatic system and the urinary tract, which results in the presence of chyle in the urine, making it appear milky white.
Alexandre Sabbah   +6 more
doaj   +1 more source

Genetics of lymphatic anomalies

open access: yes, 2014
Lymphatic anomalies include a variety of developmental and/or functional defects affecting the lymphatic vessels: sporadic and familial forms of primary lymphedema, secondary lymphedema, chylothorax and chylous ascites, lymphatic malformations, and ...
Boon, Laurence M.   +5 more
core   +1 more source

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