Results 91 to 100 of about 696,685 (294)

Advances in Drugs Targeting Lymphangiogenesis for Preventing Tumor Progression and Metastasis

Frontiers in Oncology, 2022
Metastasis of cancer cells from the primary tumor to other organs and tissues in the body is the leading cause of death in patients with malignancies. One of the principal ways cancer cells travel is through lymphatic vessels, and tumor invasion into the
Chuqi Wang, Chuqi Wang, Ming Chu
doaj   +1 more source

L1-regularized neural ranking for risk stratification and its application to prediction of time to distant metastasis in luminal node negative chemotherapy naïve breast cancer patients [PDF]

arXiv, 2021
Can we predict if an early stage cancer patient is at high risk of developing distant metastasis and what clinicopathological factors are associated with such a risk? In this paper, we propose a ranking based censoring-aware machine learning model for answering such questions.
arxiv  

Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]

, 2018
There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin, Alecu, Lucian, Cristian, Balalau, Hainarosie, Razvan, Jecan, Radu, Nitipir, Cornelia, Orlov, Cristina, Pantea Stoian, Anca, Pituru, Silviu, Poiana, Catalina, Slavu, Iulian, Tomescu, Luminita, Tulin, Raluca   +12 more
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment

Nature Communications, 2018
Tumor-associated macrophages (TAMs) are the most abundant inflammatory infiltrates in the tumor microenvironment and contribute to lymph node (LN) metastasis. However, the precise mechanisms of TAMs-induced LN metastasis remain largely unknown.
Changhao Chen, Wang He, Jian Huang, Bo Wang, Hui Li, Q. Cai, Feng Su, J. Bi, Hongwei Liu, Bin Zhang, Ning Jiang, G. Zhong, Yue Zhao, W. Dong*, Tianxin Lin   +14 more
semanticscholar   +1 more source

Functional Effects of let-7g Expression in Colon Cancer Metastasis. [PDF]

, 2019
MicroRNA regulation is crucial for gene expression and cell functions. It has been linked to tumorigenesis, development and metastasis in colorectal cancer (CRC).
Chang, Che-Mai, Chang, Wei-Chiao, Chen, Ben-Kuen, Chiu, Siou-Jin, Hsu, Wen-Li, Huang, Chien-Yu, Maio, Zhi-Feng, Tsai, Yao-Ting, Wan, Yu-Jui Yvonne, Wang, Jaw-Yuan, Wong, Henry Sung-Ching   +10 more
core  

Extent of surgery in cancer of the colon : is more better? [PDF]

, 2015
Since the introduction of total mesorectal excision as the standard approach in mid and low rectal cancer, the incidence of local recurrence has sharply declined. Similar attention to surgical technique in colon cancer (CC) has resulted in the concept of
Ceelen, Wim, Willaert, Wouter
core   +2 more sources

Metformin treatment for diabetes mellitus correlates with progression and survival in colorectal carcinoma [PDF]

, 2020
BACKGROUND: Diabetes mellitus is unfavorably associated with cancer risk. The purpose of this multi-disciplinary project was to evaluate a possible association of diabetes mellitus and other comorbidities and their treatment with progression of ...
Brown, Robert E., Cempírková, Dana, Dundr, Pavel, Gregorová, Jana, Grimmichová, Tereza, Heneberg, Petr, Janurová, Kateřina, Litschmannová, Martina, Pešta, Michal, Powell, Marta K., Třebický, Ferdinand   +10 more
core   +1 more source

Lymphatic metastasis of tumour; persistent transport of cells [PDF]

Experientia, 1979
A model of lymphatic metastasis established by injecting Walker rat carcinoma cells into the rat footpad was used to study the output of tumour cells from the footpad. The lymphatic efferent from the footpad was cannulated in a group of rats with advanced neoplasm; it was shown that the output of tumour cells was continuous over periods up to 90 min ...
Ian Carr, Jean Carr, B. Dreher, C. R. Franks   +3 more
openaire   +3 more sources

Loss of GATA6 expression promotes lymphatic metastasis in bladder cancer

The FASEB Journal, 2020
Lymph node metastasis is associated with tumor relapse and poor patient prognosis in bladder cancer. However, the mechanisms by which bladder carcinoma cells induce lymphangiogenesis and further promote metastasis in the lymphatic system remain unclear ...
Chanjuan Wang, Qing-Hua Liu, Ming Huang, Qianghua Zhou, Xiaoyu Zhang, Jingtong Zhang, Ruihui Xie, Yanqi Yu, Shang-Liang Chen, Jianbing Fan, Xu Chen   +10 more
semanticscholar   +1 more source