Results 81 to 90 of about 136,324 (301)

Tumour cells express functional lymphatic endothelium-specific hyaluronan receptor in vitro and in vivo: Lymphatic mimicry promotes oral oncogenesis?

Oncogenesis, 2021
Lymphatic metastasis represents the main route of tumour cell dissemination in oral squamous cell carcinoma (OSCC). Yet, there are no FDA-approved therapeutics targeting cancer-related lymphangiogenesis to date.
Sini Karinen, Krista Juurikka, Roosa Hujanen, Wafa Wahbi, Elin Hadler-Olsen, Gunbjørg Svineng, Kari K. Eklund, Tuula Salo, Pirjo Åström, Abdelhakim Salem   +9 more
doaj   +1 more source

Sentinel lymph node in early stage ovarian cancer; a literature review [PDF]

, 2018
Although sentinel lymph node mapping has been widely implemented in gynecological malignancies in order to minimize the number of unnecessary lymph node dissections and to diminish postoperative morbidity rate, little is known about ovarian cancer ...
Bacalbasa, Nicolae, Balescu, Irina, Brasoveanu, Vladislav, Brezean, Iulian, Vilcu, Mihaela   +4 more
core   +3 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Integrin α6‐containing extracellular vesicles promote lymphatic remodelling for pre‐metastatic niche formation in lymph nodes via interplay with CD151

Journal of Extracellular Vesicles
Heterogeneous extracellular vesicles (EVs) from various types of tumours are acknowledged for inducing the formation of pre‐metastatic “niches” in draining lymph nodes (LNs) to promote lymphatic metastasis.
Yan Lin, Hanhao Zheng, Linpei Jia, Yuming Luo, Dingwen Zhang, Mingjie An, Mingrui Pang, Xiayao Diao, Wenjie Li, Jiancheng Chen, Yuanlong Li, Daiyin Liu, Zhicong Liu, Jian Huang, Tianxin Lin, Changhao Chen   +15 more
doaj   +1 more source

An overview of the focus of the International Gap Junction Conference 2017 and Future Perspectives [PDF]

, 2018
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Kwak, Brenda R., Martin, Patricia E.
core   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Progress in the Mechanism of Lymphangiogenesis and Lymphatic Metastasis 
of Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2021
Lung cancer ranks the first cancer-related morbidity and mortality in China. Tumor metastasis always predicts the poor prognosis for patients. Moreover, lymphatic metastasis is one of the most significant predictors of poor prognosis in patients with non-
Xiayao DIAO, Chao GUO, Shanqing LI
doaj   +1 more source

Expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocacinoma [PDF]

, 2010
Background To study on expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocarcinoma (GC). Methods Expressions of CD133 protein by immunostaining (99 cases) and CD133 mRNA by semi-quantitative RT-PCR ...
Ji-wei Yu, Peng Zhang, Ju-gang Wu, Sheng-hua Wu, Xiao-qiang Li, Shi-ting Wang, Rui-qi Lu, Xiao-chun Ni, Bo-jian Jiang   +8 more
core   +2 more sources

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Malignant priapism due to penile metastases. Case series and literature review [PDF]

, 2016
Malignant priapism secondary to penile metastases is a rare condition. This term was originally used by Peacock in 1938 to describe a condition of painful induration and erection of the penis due to metastatic infiltration by a neoplasm.
DE DOMINICIS, Carlo, DE LUCA, Francesco, Manzi, Emy, Maurizi, Angela, Ralph, David, Shabbir, Majed, Zacharakis, Evangelos, Zanghì, Antonio   +7 more
core   +2 more sources