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Mechanisms and Clinical Significance of Tumor Lymphatic Invasion
Tumor-associated lymphatic vessels play an important role in tumor progression, mediating lymphatic dissemination of malignant cells to tumor-draining lymph nodes and regulating tumor immunity. An early, necessary step in the lymphatic metastasis cascade
Noriki Fujimoto, Lothar C. Dieterich
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Ultrasound mapping of lymph node and subcutaneous metastases in patients with cutaneous melanoma: Results of a prospective multicenter study [PDF]
Background: Ultrasound (sonography, B-mode sonography, ultrasonography) examination improves the sensitivity in more than 25% compared to the clinical palpation, especially after surgery on the regional lymph node area.
Blum, A.+5 more
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Network development in biological gels: role in lymphatic vessel development [PDF]
In this paper, we present a model that explains the prepatterning of lymphatic vessel morphology in collagen gels. This model is derived using the theory of two phase rubber material due to Flory and coworkers and it consists of two coupled fourth order ...
Roose, Tiina, Fowler, A. C.
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Dissecting the Lymphatic System to Predict Melanoma Metastasis [PDF]
Melanoma is the most lethal form of skin cancer in the United States. Current American Joint Committee on Cancer (AJCC) staging uses Breslow depth and ulceration as the two primary tumor factors that predict metastatic risk in cutaneous melanoma. Early disease stages are generally associated with high survival rates.
Arturas Ziemys+2 more
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Background Preoperative positron emission tomography/computed tomography (PET/CT) is recommended as a guideline for staging of lung cancer. However, for patients with pulmonary ground‐glass opacity (GGO) nodules who are supposed to have a relatively low ...
Yi‐Chung Chen+8 more
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Oral treatment with the dual-receptor tyrosine kinase inhibitor AEE788 effectively reduces the number of peritumoral lymphatic vessels and the incidence of lymph node metastasis in nude mice with human HT29 colon cancer cells growing in the cecum ...
Robert B. Rebhun+5 more
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PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor
Nasopharyngeal carcinoma (NPC) is one of the most malignant tumors in southern China and Asia, and lymph node metastasis is an important cause for treatment failure.
Chuanghua Luo+13 more
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Future Needs in Mast Cell Biology. [PDF]
The pathophysiological roles of mast cells are still not fully understood, over 140 years since their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct "subpopulations" of mast cells based on a relatively small ...
de Paulis, Amato+3 more
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Lymphangiogenesis and lymphatic metastasis in breast cancer [PDF]
Lymphatic metastasis is the main prognostic factor for survival of patients with breast cancer and other epithelial malignancies. Mounting clinical and experimental data suggest that migration of tumor cells into the lymph nodes is greatly facilitated by lymphangiogenesis, a process that generates new lymphatic vessels from pre-existing lymphatics with
Kelly Hall+3 more
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Predicting Lung Cancer's Metastats' Locations Using Bioclinical Model [PDF]
Lung cancer is a leading cause of cancer-related deaths worldwide. The spread of the disease from its primary site to other parts of the lungs, known as metastasis, significantly impacts the course of treatment. Early identification of metastatic lesions is crucial for prompt and effective treatment, but conventional imaging techniques have limitations
arxiv +1 more source