Results 31 to 40 of about 369,774 (289)

Limfangiogenesis sebagai jalur alternatif metastasis kanker

Lymphangiogenesis as an alternative pathway for cancer metastasis

open access: yesJurnal Kedokteran Gigi Universitas Padjadjaran, 2016
Pendahuluan: Metastasis merupakan salah satu sifat kanker yang dapat terjadi melalui berbagai cara yaitu melalui rongga tubuh, melalui pembuluh limfatik, dan melalui pembuluh darah. Pembuluh limfatik merupakan jalur penting dalam metastasis kanker karena
Pudji Handayani   +2 more
doaj   +1 more source

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

open access: yesCell Death and Disease, 2023
Lymphatic metastasis is the most common pattern of bladder cancer (BCa) metastasis and has an extremely poor prognosis. Emerging evidence shows that ubiquitination plays crucial roles in various processes of tumors, including tumorigenesis and ...
Kanghua Xiao   +10 more
doaj   +1 more source

Potential therapeutic strategies for lymphatic metastasis [PDF]

open access: yesMicrovascular Research, 2007
Physiologically, the lymphatic system regulates fluid volume in the interstitium and provides a conduit for immune cells to travel to lymph nodes, but pathologically, the lymphatic system serves as a primary escape route for cancer cells. Lymphatic capillaries have a thin discontinuous basement membrane, lack pericyte coverage and often contain ...
Bernadette M M, Zwaans   +1 more
openaire   +2 more sources

Are we nearly there yet? Coverage and compliance of mass drug administration for lymphatic filariasis elimination. [PDF]

open access: yes, 2015
Lymphatic filariasis has been targeted for elimination by 2020, and a threshold of 65% coverage of mass drug administration (MDA) has been adopted by the Global Programme to Eliminate Lymphatic Filariasis (GPELF).
Alexander, Neal DE
core   +1 more source

Biomechanical aspects of the normal and cancer-associated lymphatic system

open access: yes, 2022
The presence of lymph node metastasis is a robust adverse prognostic marker in cancer patients. Solid cancers coopt the existing lymphatic system and induce lymphangiogenesis in the process of lymphatic metastatic spread.
Silvera Delgado, Carlos Alejandro   +12 more
core   +1 more source

Anlotinib suppresses lymphangiogenesis and lymphatic metastasis in lung adenocarcinoma through a process potentially involving VEGFR-3 signaling

open access: yesCancer Biology & Medicine, 2020
Objective: Lymphatic metastasis is one of the leading causes of malignancy dispersion in various types of cancer. However, few anti-lymphangiogenic drugs have been approved for clinical use to date. Therefore, new therapies to block lymphangiogenesis are
Tingting Qin   +7 more
doaj   +1 more source

RAF1 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating LAGE1: an experimental research

open access: yesJournal of Translational Medicine, 2022
Background Lymphatic metastasis was an independent prognostic risk factor for hypopharyngeal carcinoma and was the main cause of treatment failure. The purpose of this study was to screen the differential genes and investigate the mechanism of lymphatic ...
Yanshi Li   +6 more
doaj   +1 more source

Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]

open access: yes, 2005
Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Jauch, Karl-Walter   +2 more
core   +1 more source

Targeting Receptor Tyrosine Kinase on Lymphatic Endothelial Cells for the Therapy of Colon Cancer Lymph Node Metastasis

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
Oral treatment with the dual-receptor tyrosine kinase inhibitor AEE788 effectively reduces the number of peritumoral lymphatic vessels and the incidence of lymph node metastasis in nude mice with human HT29 colon cancer cells growing in the cecum ...
Robert B. Rebhun   +5 more
doaj   +1 more source

Surgical outcomes for cutaneous squamous cell carcinoma of the auricle

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery, 2023
Background Cutaneous squamous cell carcinoma (CSCC) on the auricle is believed to carry a higher risk of metastatic spread. The rates of lymphatic metastasis reported in the literature have varied widely.
Constantin Manole   +2 more
doaj   +1 more source

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