Results 31 to 40 of about 136,324 (301)

The Outcome of Patients with Melanoma Is Not Associated with the Time Point of Lymphatic Mapping with Respect to Excisional Biopsy of the Primary Tumor [PDF]

open access: yes, 2010
Background: Sentinel lymph node biopsy (SLNB) has become the standard care for melanoma and is an important diagnostic procedure. It has been doubted whether lymphoscintigraphy detects the correct sentinel lymph node (SLN) when excision of the tumor and ...
Baumert, Jens   +7 more
core   +1 more source

Limfangiogenesis sebagai jalur alternatif metastasis kanker

Lymphangiogenesis as an alternative pathway for cancer metastasis

open access: yesJurnal Kedokteran Gigi Universitas Padjadjaran, 2016
Pendahuluan: Metastasis merupakan salah satu sifat kanker yang dapat terjadi melalui berbagai cara yaitu melalui rongga tubuh, melalui pembuluh limfatik, dan melalui pembuluh darah. Pembuluh limfatik merupakan jalur penting dalam metastasis kanker karena
Pudji Handayani   +2 more
doaj   +1 more source

RAF1 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating LAGE1: an experimental research

open access: yesJournal of Translational Medicine, 2022
Background Lymphatic metastasis was an independent prognostic risk factor for hypopharyngeal carcinoma and was the main cause of treatment failure. The purpose of this study was to screen the differential genes and investigate the mechanism of lymphatic ...
Yanshi Li   +6 more
doaj   +1 more source

Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression [PDF]

open access: yes, 2016
Hypoxia-inducible factor-1α (HIF-1α) mediates the response to hypoxia or other stimuli, such as growth factors, including endothelin-1 (ET-1), to promote malignant progression in numerous tumors.
Bagnato, Anna   +6 more
core   +1 more source

Anlotinib suppresses lymphangiogenesis and lymphatic metastasis in lung adenocarcinoma through a process potentially involving VEGFR-3 signaling

open access: yesCancer Biology & Medicine, 2020
Objective: Lymphatic metastasis is one of the leading causes of malignancy dispersion in various types of cancer. However, few anti-lymphangiogenic drugs have been approved for clinical use to date. Therefore, new therapies to block lymphangiogenesis are
Tingting Qin   +7 more
doaj   +1 more source

Surgical outcomes for cutaneous squamous cell carcinoma of the auricle

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery, 2023
Background Cutaneous squamous cell carcinoma (CSCC) on the auricle is believed to carry a higher risk of metastatic spread. The rates of lymphatic metastasis reported in the literature have varied widely.
Constantin Manole   +2 more
doaj   +1 more source

Mechanisms and Clinical Significance of Tumor Lymphatic Invasion

open access: yesCells, 2021
Tumor-associated lymphatic vessels play an important role in tumor progression, mediating lymphatic dissemination of malignant cells to tumor-draining lymph nodes and regulating tumor immunity. An early, necessary step in the lymphatic metastasis cascade
Noriki Fujimoto, Lothar C. Dieterich
doaj   +1 more source

Targeting Receptor Tyrosine Kinase on Lymphatic Endothelial Cells for the Therapy of Colon Cancer Lymph Node Metastasis

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
Oral treatment with the dual-receptor tyrosine kinase inhibitor AEE788 effectively reduces the number of peritumoral lymphatic vessels and the incidence of lymph node metastasis in nude mice with human HT29 colon cancer cells growing in the cecum ...
Robert B. Rebhun   +5 more
doaj   +1 more source

Risk factors for lymphatic and hematogenous metastasis after diagnosis of cutaneous Melanoma in Taiwan

open access: yesJournal of the Formosan Medical Association, 2022
Background: Risk factors of lymphatic and hematogenous metastasis in cutaneous melanoma remained unclear in Asian population. This study aimed to identify clinical and histopathological factors to predict metastatic pathways in cutaneous melanoma in ...
Che-Chia Hsu   +5 more
doaj   +1 more source

Urothelial bladder carcinoma metastasizing to the eye: a systematic review and case report [PDF]

open access: yes, 2019
The eye is a rare site for disseminated malignancies; nevertheless, several tumors may metastasize to ocular structures. Few cases of urothelial and bladder cancer with eye involvement have been described in the literature thus far.
Brunelli, Matteo   +12 more
core   +1 more source

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