Results 11 to 20 of about 95,943 (256)
PLoS ONE, 2021 MACC1 gene is a newly discovered gene and plays an important role in the metastasis of colorectal cancer (CRC). The objective of this study was to investigate whether MACC1 is an independent factor associated with lymphatic metastasis in CRC patients. We
Zheying Zhang +4 more
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Mechanisms of lymphatic metastasis [PDF]
Journal of Clinical Investigation, 2014 Malignant tumors release growth factors such as VEGF-C to induce lymphatic vessel expansion (lymphangiogenesis) in primary tumors and in draining sentinel LNs, thereby promoting LN metastasis. Surprising recent evidence suggests that lymphatic vessels do not merely represent passive channels for tumor spread, but that they may actively promote tumor ...
Karaman Sinem, Detmar Michael
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Bacterial Lymphatic Metastasis in Infection and Immunity [PDF]
Cells, 2021 Lymphatic vessels permeate tissues around the body, returning fluid from interstitial spaces back to the blood after passage through the lymph nodes, which are important sites for adaptive responses to all types of pathogens. Involvement of the lymphatics in the pathogenesis of bacterial infections is not well studied.
Matthew K. Siggins, Shiranee Sriskandan
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Therapeutic Advances in Medical Oncology, 2020 Background: The aim of this study was to clarify the features and prognostic significance of isolated para-aortic lymphatic metastasis of endometrial cancer.
Jianbin Guo +5 more
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Lymphatic metastasis due to glioblastoma [PDF]
Neurosciences, 2016 Glioblastomas are the most common malignant primary brain tumor. Only 0.2%-0.5% of cases metastasise outside the brain.[1][1],[2][2] We present a rare case of glioblastoma with bilateral cervical lymph node metastases.
Wassati, Husam, Loo, Suat W., Low, Hu L.
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Frontiers in Oncology, 2022 ObjectiveSince there are few studies exploring genes associated with lymphatic metastasis of thyroid carcinoma (THCA), this study was conducted to explore genes associated with lymphatic metastasis of THCA and to investigate the relationship with immune ...
Linfeng Wu +14 more
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TGF-β signaling in lymphatic vascular vessel formation and maintenance
Frontiers in Physiology, 2022 Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
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Lymphatic System Metastasis [PDF]
British Journal of Cancer, 1981 For the physician who works at bedside or clinic with cancer patients, knowledge of lymphatic spread of tumors is based on the great anatomic work by Rouviere published in the early years of this century. In 1972, Haagensen's text on the lymphatics in cancer became the useful clinical counterpart of that approach, showing by surgical dissection and the
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Endothelial-specific depletion of TGF-β signaling affects lymphatic function
Inflammation and Regeneration, 2021 Background Transforming growth factor (TGF)-β is a multifunctional cytokine involved in cell differentiation, cell proliferation, and tissue homeostasis.
Kunpei Fukasawa +7 more
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Microfluidic System to Analyze the Effects of Interleukin 6 on Lymphatic Breast Cancer Metastasis
Frontiers in Bioengineering and Biotechnology, 2021 Metastasis is the primary cause of a large number of cancer-associated deaths. By portraying the precise environment of the metastasis process in vitro, the microfluidic system provides useful insights on the mechanisms underlying cancer cell migration ...
Hyeon-Yeol Cho +5 more
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