Results 21 to 30 of about 400,896 (294)

Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]

open access: yes, 2009
Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
core   +1 more source

Progression of Metastasis through Lymphatic System [PDF]

open access: yesCells, 2021
Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate. Thus, it is important to understand the mechanisms by which lymph node metastases progress and how they can be targeted to provide therapeutic benefits.
Hengbo Zhou   +2 more
openaire   +3 more sources

The effect of lymphatic pumping on mouse melanoma metastasis

open access: yes, 2022
I showed that lymphatic pumping decreased melanoma metastasis in young, but not old ...
Walsh, Christopher
core   +2 more sources

A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development [PDF]

open access: yes, 2010
The molecular mechanisms that regulate the earliest steps of lymphatic vascular system development are unknown. To identify regulators of lymphatic competence and commitment, we used an in vitro vascular assay with mouse embryonic stem cell-derived ...
Dabouras, Vasilios   +11 more
core   +1 more source

Lymphatic System Metastasis [PDF]

open access: yesBritish Journal of Cancer, 1981
For the physician who works at bedside or clinic with cancer patients, knowledge of lymphatic spread of tumors is based on the great anatomic work by Rouviere published in the early years of this century. In 1972, Haagensen's text on the lymphatics in cancer became the useful clinical counterpart of that approach, showing by surgical dissection and the
openaire   +2 more sources

Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]

open access: yes, 2011
The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine   +9 more
core   +2 more sources

Endothelial-specific depletion of TGF-β signaling affects lymphatic function

open access: yesInflammation and Regeneration, 2021
Background Transforming growth factor (TGF)-β is a multifunctional cytokine involved in cell differentiation, cell proliferation, and tissue homeostasis.
Kunpei Fukasawa   +7 more
doaj   +1 more source

Microfluidic System to Analyze the Effects of Interleukin 6 on Lymphatic Breast Cancer Metastasis

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Metastasis is the primary cause of a large number of cancer-associated deaths. By portraying the precise environment of the metastasis process in vitro, the microfluidic system provides useful insights on the mechanisms underlying cancer cell migration ...
Hyeon-Yeol Cho   +5 more
doaj   +1 more source

Lymphangiogenesis and lymphatic metastasis in breast cancer [PDF]

open access: yesPathophysiology, 2010
Lymphatic metastasis is the main prognostic factor for survival of patients with breast cancer and other epithelial malignancies. Mounting clinical and experimental data suggest that migration of tumor cells into the lymph nodes is greatly facilitated by lymphangiogenesis, a process that generates new lymphatic vessels from pre-existing lymphatics with
Sophia, Ran   +3 more
openaire   +2 more sources

Polysaccharides From Lentinus Edodes Inhibits Lymphangiogenesis via the Toll-Like Receptor 4/JNK Pathway of Cancer-Associated Fibroblasts

open access: yesFrontiers in Oncology, 2021
Polysaccharides from Lentinus edodes (L. edodes) have been successfully used as adjuvant chemotherapy drug to treat lymphatic metastasis in some malignancies, such as colorectal cancer (CRC), lung cancer and gastric cancer.
Yuanyuan Wang   +10 more
doaj   +1 more source

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