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Aberrant lymphatic system function has been increasingly implicated in pathologies such as lymphedema, organ transplant rejection, cardiovascular disease, obesity, and neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease ...
Faisal Masood+5 more
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In the present study, we aimed to identify the normal hindlimb lymphatic systems in rats and compare them with the detours after lymphatic flow blockage.
Yuiko Suzuki+4 more
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Microenvironmental signals produced during development or inflammation stimulate lymphatic endothelial cells to undergo lymphangiogenesis, in which they sprout, proliferate, and migrate to expand the vascular network.
Delayna Paulson+10 more
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Obesity and metabolic syndrome pose a significant risk for developing cardiovascular disease and remain a critical healthcare challenge. Given the lymphatic system’s role as a nexus for lipid absorption, immune cell trafficking, interstitial fluid and ...
Yang Lee+2 more
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Lymphatic Vessel Invasion in Routine Pathology Reports of Papillary Thyroid Cancer
PurposeIt is not mandatory to report lymphatic vessel invasion in pathology reports of papillary thyroid cancer (PTC) according to the current Union for International Cancer Control (UICC) TNM (tumor, nodes, and metastases) classification. However, there
Costanza Chiapponi+7 more
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The lymphatic vasculature provides an essential route to drain fluid, macromolecules, and immune cells from the interstitium as lymph, returning it to the bloodstream where the thoracic duct meets the subclavian vein.
Amanda M. Peluzzo+4 more
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Lymphatic Vessels at the Heart of the Matter [PDF]
Emergent research in the past decades has brought to light the importance of lymphatic vessels in tissue homeostasis, immunity, metabolism, and inflammation. In Nature, Klotz et al. (2015) demonstrate that cardiac lymphatics have a unique ontology compared to visceral lymphatics and that promoting their growth can improve cardiac function following ...
Natasha L. Harvey+2 more
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Lymphatic vascular response to acute inflammation. [PDF]
During acute inflammation, functioning lymphatics are believed to reduce edema and to provide a transiting route for immune cells, but the extent at which the dermal lymphatic remodeling impacts lymphatic transport or the factors regulating these changes
Pier-Anne Lachance+2 more
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Multiple aspects of lymphatic dysfunction in an ApoE−/− mouse model of hypercholesterolemia
Introduction: Rodent models of cardiovascular disease have uncovered various types of lymphatic vessel dysfunction that occur in association with atherosclerosis, type II diabetes and obesity.
Michael J. Davis+8 more
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A 1D-0D-3D coupled model for simulating blood flow and transport processes in breast tissue [PDF]
In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and tissue of the breast.
arxiv +1 more source