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Lymphatic Vessel Regression and Its Therapeutic Applications: Learning From Principles of Blood Vessel Regression

open access: yesFrontiers in Physiology, 2022
Aberrant lymphatic system function has been increasingly implicated in pathologies such as lymphedema, organ transplant rejection, cardiovascular disease, obesity, and neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease ...
Mark I Rosenblatt   +2 more
exaly   +3 more sources

Comparison of normal hindlimb lymphatic systems in rats with detours present after lymphatic flow blockage.

open access: yesPLoS ONE, 2021
In the present study, we aimed to identify the normal hindlimb lymphatic systems in rats and compare them with the detours after lymphatic flow blockage.
Yuiko Suzuki   +4 more
doaj   +1 more source

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Microenvironmental signals produced during development or inflammation stimulate lymphatic endothelial cells to undergo lymphangiogenesis, in which they sprout, proliferate, and migrate to expand the vascular network.
Delayna Paulson   +10 more
doaj   +1 more source

Lymphatic Collecting Vessel: New Perspectives on Mechanisms of Contractile Regulation and Potential Lymphatic Contractile Pathways to Target in Obesity and Metabolic Diseases

open access: yesFrontiers in Pharmacology, 2022
Obesity and metabolic syndrome pose a significant risk for developing cardiovascular disease and remain a critical healthcare challenge. Given the lymphatic system’s role as a nexus for lipid absorption, immune cell trafficking, interstitial fluid and ...
Yang Lee   +2 more
doaj   +1 more source

Lymphatic Vessel Invasion in Routine Pathology Reports of Papillary Thyroid Cancer

open access: yesFrontiers in Medicine, 2022
PurposeIt is not mandatory to report lymphatic vessel invasion in pathology reports of papillary thyroid cancer (PTC) according to the current Union for International Cancer Control (UICC) TNM (tumor, nodes, and metastases) classification. However, there
Costanza Chiapponi   +7 more
doaj   +1 more source

Differential regulation of lymphatic junctional morphology and the potential effects on cardiovascular diseases

open access: yesFrontiers in Physiology, 2023
The lymphatic vasculature provides an essential route to drain fluid, macromolecules, and immune cells from the interstitium as lymph, returning it to the bloodstream where the thoracic duct meets the subclavian vein.
Amanda M. Peluzzo   +4 more
doaj   +1 more source

Lymphatic vascular response to acute inflammation. [PDF]

open access: yesPLoS ONE, 2013
During acute inflammation, functioning lymphatics are believed to reduce edema and to provide a transiting route for immune cells, but the extent at which the dermal lymphatic remodeling impacts lymphatic transport or the factors regulating these changes
Pier-Anne Lachance   +2 more
doaj   +1 more source

Multiple aspects of lymphatic dysfunction in an ApoE−/− mouse model of hypercholesterolemia

open access: yesFrontiers in Physiology, 2023
Introduction: Rodent models of cardiovascular disease have uncovered various types of lymphatic vessel dysfunction that occur in association with atherosclerosis, type II diabetes and obesity.
Michael J. Davis   +8 more
doaj   +1 more source

Characterization, Localization and Patterning of Lymphatics and Blood Vessels in Oral Squamous Cell Carcinoma: A Comparative Study Using D2-40 and CD-34 IHC Marker [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Objectives: Lymphatic metastasis has always been regarded as a major prognostic indicator for disease progression and as a guide for therapeutic strategies to oral squamous cell carcinoma (OSCC).
Deshant Agarwal   +7 more
doaj   +1 more source

Size adjustment suture technique for lymphaticovenular anastomosis

open access: yesJournal of Plastic Surgery and Hand Surgery, 2023
In this report, we describe a super microsurgical technique that enables rapid and accurate anastomosis while adjusting for caliber differences when anastomosing a small-caliber lymphatic vessel and a vein with a larger caliber, which is frequently ...
Satoshi Onoda   +2 more
doaj   +1 more source

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