Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets. [PDF]
Signal Transduct Target TherLymphatic vessels, comprising the secondary circulatory system in human body, play a multifaceted role in maintaining homeostasis among various tissues and organs.
Hu Z +7 more
europepmc +3 more sources
Renal lymphatic vessel dynamics.
Am J Physiol Renal Physiol, 2020 Similar to other organs, renal lymphatics remove excess fluid, solutes, and macromolecules from the renal interstitium. Given the kidney’s unique role in maintaining body fluid homeostasis, renal lymphatics may be critical in this process. However, little is known regarding the pathways involved in renal lymphatic vessel function, and there are no ...
Shelton EL +4 more
europepmc +6 more sources
Confocal Imaging: Blood and Lymphatic Capillaries [PDF]
The Scientific World Journal, 2006 Traditional imaging techniques are quite limited for the study of the relationship between blood vessels and lymphatic vessels. Therefore, a new imaging technique is required based on blood vessel and lymphatic endothelial-specific molecular markers.
Yingjie Cui
doaj +3 more sources
Investigating lymphangiogenesis in vitro and in vivo using engineered human lymphatic vessel networks. [PDF]
Proc Natl Acad Sci U S A, 2021 Significance Lymphatic vessel networks are important for various biological processes; thus, incorporating them into engineered constructs can have both research and clinical implications.
Landau S +9 more
europepmc +2 more sources
Digging deeper into lymphatic vessel formation
BMC Cell Biology, 2011 Background Abnormal lymphatic vessel formation (lymphangiogenesis) is associated with different pathologies such as cancer, lymphedema, psoriasis and graft rejection.
Thiry Marc +9 more
doaj +4 more sources
The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma [PDF]
Journal of Experimental & Clinical Cancer Research, 2009 Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Zhang Renhua +3 more
doaj +5 more sources
Lymphatic Vessel Invasion in Routine Pathology Reports of Papillary Thyroid Cancer. [PDF]
Front Med (Lausanne), 2022 PurposeIt is not mandatory to report lymphatic vessel invasion in pathology reports of papillary thyroid cancer (PTC) according to the current Union for International Cancer Control (UICC) TNM (tumor, nodes, and metastases) classification. However, there
Chiapponi C +7 more
europepmc +2 more sources
Lymphatic Vessel Regression and Its Therapeutic Applications: Learning From Principles of Blood Vessel Regression. [PDF]
Front Physiol, 2022 Aberrant lymphatic system function has been increasingly implicated in pathologies such as lymphedema, organ transplant rejection, cardiovascular disease, obesity, and neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease ...
Masood F +5 more
europepmc +2 more sources
Clinical implications of increased lymph vessel density in the lymphatic metastasis of early-stage invasive cervical carcinoma: a clinical immunohistochemical method study [PDF]
BMC Cancer, 2009 Background Cervical cancer is the most common malignant gynecological cancer, and lymphatic metastasis can occur in the early stage of tumor growth. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a marker for lymphatic endothelium, provides
Yu Hao, Zhang Shi-qian, Zhang Lin-lin
doaj +4 more sources
Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation. [PDF]
Front Physiol, 2022 The lymphatic system is crucial for the maintenance of interstitial fluid and protein homeostasis. It has important roles in collecting excess plasma and interstitial fluid leaked from blood vessels, lipid absorption and transportation in the digestive ...
Ujiie N, Kume T.
europepmc +2 more sources