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Lymphatic vessel: Origin, heterogeneity, biological functions and therapeutic targets [PDF]
Signal Transduction and Targeted TherapyLymphatic vessels, comprising the secondary circulatory system in human body, play a multifaceted role in maintaining homeostasis among various tissues and organs.
Zhaoliang Hu +7 more
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Renal lymphatic vessel dynamics.
Am J Physiol Renal Physiol, 2020 Similar to other organs, renal lymphatics remove excess fluid, solutes, and macromolecules from the renal interstitium. Given the kidney's unique role in maintaining body fluid homeostasis, renal lymphatics may be critical in this process.
Shelton EL +4 more
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Biomechanical control of lymphatic vessel physiology and functions. [PDF]
Cell Mol Immunol, 2023 The ever-growing research on lymphatic biology has clearly identified lymphatic vessels as key players that maintain human health through their functional roles in tissue fluid homeostasis, immunosurveillance, lipid metabolism and inflammation.
Angeli V, Lim HY.
europepmc +2 more sources
Inhibiting corneal transplantation rejection via lymphatic vessel ligation in a novel murine model [PDF]
Scientific ReportsThe lymphatic system is a crucial contributor to allograft rejection after corneal transplantation. However, no surgical procedures for the central pathway where conjunctival lymphatic vessels converge have been investigated.
Ami Igarashi +4 more
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Lymphatic Vessel Invasion in Routine Pathology Reports of Papillary Thyroid Cancer [PDF]
Frontiers in Medicine, 2022 PurposeIt is not mandatory to report lymphatic vessel invasion in pathology reports of papillary thyroid cancer (PTC) according to the current Union for International Cancer Control (UICC) TNM (tumor, nodes, and metastases) classification. However, there
Costanza Chiapponi +7 more
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BMC Cancer, 2017 Background Lymphatic vessel density and lymphovascular invasion are commonly assessed to identify the clinicopathological outcomes in breast cancer. However, the prognostic values of them on patients’ survival are still uncertain.
Song Zhang +5 more
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Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation [PDF]
Frontiers in Physiology, 2022 The lymphatic system is crucial for the maintenance of interstitial fluid and protein homeostasis. It has important roles in collecting excess plasma and interstitial fluid leaked from blood vessels, lipid absorption and transportation in the digestive ...
Naoto Ujiie, Tsutomu Kume
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Nature Communications, 2018 VEGF-C is a key regulator of lymphatic development. Here, Zhang et al. show that while complete loss of its receptor VEGFR3 results in vessel hypoplasia, mosaic loss of VEGFR3 leads to hyperplasia through induction of cell proliferation in neighboringnon-
Yan Zhang +6 more
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Hydrogen sulfide donor activates AKT-eNOS signaling and promotes lymphatic vessel formation. [PDF]
PLoS ONE, 2023 The lymphatic network is pivotal for various physiological functions in the human body. Accumulated evidence supports the role of therapeutic lymphangiogenesis in the treatment of several pathologies.
Ravi Varma Aithabathula +7 more
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Blood and lymphatic vessel formation. [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Blood and lymphatic vessels deliver oxygen and nutrients, remove waste and CO2, and regulate interstitial pressure in tissues and organs. These vessels begin life early in embryogenesis using transcription factors and signaling pathways that regulate ...
V. Bautch, K. Caron
semanticscholar +3 more sources