Results 1 to 10 of about 50,153 (264)

Inhibiting corneal transplantation rejection via lymphatic vessel ligation in a novel murine model [PDF]

Scientific Reports
The lymphatic system is a crucial contributor to allograft rejection after corneal transplantation. However, no surgical procedures for the central pathway where conjunctival lymphatic vessels converge have been investigated.
Ami Igarashi, Takahiko Hayashi, Toshiki Shimizu, Kentaro Yuda, Satoru Yamagami   +4 more
doaj   +2 more sources

Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation [PDF]

Frontiers in Physiology, 2022
The lymphatic system is crucial for the maintenance of interstitial fluid and protein homeostasis. It has important roles in collecting excess plasma and interstitial fluid leaked from blood vessels, lipid absorption and transportation in the digestive ...
Naoto Ujiie, Tsutomu Kume
doaj   +2 more sources

Lymphatic vessel: Origin, heterogeneity, biological functions and therapeutic targets [PDF]

Signal Transduction and Targeted Therapy
Lymphatic vessels, comprising the secondary circulatory system in human body, play a multifaceted role in maintaining homeostasis among various tissues and organs.
Zhaoliang Hu, Xushi Zhao, Zhonghua Wu, Bicheng Qu, Minxian Yuan, Yanan Xing, Yongxi Song, Zhenning Wang   +7 more
doaj   +2 more sources

Hydrogen sulfide donor activates AKT-eNOS signaling and promotes lymphatic vessel formation. [PDF]

PLoS ONE, 2023
The lymphatic network is pivotal for various physiological functions in the human body. Accumulated evidence supports the role of therapeutic lymphangiogenesis in the treatment of several pathologies.
Ravi Varma Aithabathula, Naveed Pervaiz, Ishita Kathuria, Mallory Swanson, Udai P Singh, Santosh Kumar, Frank Park, Bhupesh Singla   +7 more
doaj   +2 more sources

Lymphatic Vessel Regression and Its Therapeutic Applications: Learning From Principles of Blood Vessel Regression

Frontiers in Physiology, 2022
Aberrant lymphatic system function has been increasingly implicated in pathologies such as lymphedema, organ transplant rejection, cardiovascular disease, obesity, and neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease ...
Faisal Masood, Rohan Bhattaram, Mark I. Rosenblatt, Andrius Kazlauskas, Jin-Hong Chang, Dimitri T. Azar   +5 more
doaj   +1 more source

Comparison of normal hindlimb lymphatic systems in rats with detours present after lymphatic flow blockage.

PLoS ONE, 2021
In the present study, we aimed to identify the normal hindlimb lymphatic systems in rats and compare them with the detours after lymphatic flow blockage.
Yuiko Suzuki, Yukari Nakajima, Toshio Nakatani, Mayumi Okuwa, Junko Sugama   +4 more
doaj   +1 more source

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation

Frontiers in Cell and Developmental Biology, 2021
Microenvironmental signals produced during development or inflammation stimulate lymphatic endothelial cells to undergo lymphangiogenesis, in which they sprout, proliferate, and migrate to expand the vascular network.
Delayna Paulson, Delayna Paulson, Rebecca Harms, Rebecca Harms, Cody Ward, Cody Ward, Mackenzie Latterell, Mackenzie Latterell, Gregory J. Pazour, Darci M. Fink, Darci M. Fink   +10 more
doaj   +1 more source

Lymphatic Collecting Vessel: New Perspectives on Mechanisms of Contractile Regulation and Potential Lymphatic Contractile Pathways to Target in Obesity and Metabolic Diseases

Frontiers in Pharmacology, 2022
Obesity and metabolic syndrome pose a significant risk for developing cardiovascular disease and remain a critical healthcare challenge. Given the lymphatic system’s role as a nexus for lipid absorption, immune cell trafficking, interstitial fluid and ...
Yang Lee, Scott D. Zawieja, Mariappan Muthuchamy   +2 more
doaj   +1 more source

Lymphatic Vessel Invasion in Routine Pathology Reports of Papillary Thyroid Cancer

Frontiers in Medicine, 2022
PurposeIt is not mandatory to report lymphatic vessel invasion in pathology reports of papillary thyroid cancer (PTC) according to the current Union for International Cancer Control (UICC) TNM (tumor, nodes, and metastases) classification. However, there
Costanza Chiapponi, Hakan Alakus, Matthias Schmidt, Michael Faust, Christiane J. Bruns, Reinhard Büttner, Marie-Lisa Eich, Anne M. Schultheis   +7 more
doaj   +1 more source

Lymphatic vascular response to acute inflammation. [PDF]

PLoS ONE, 2013
During acute inflammation, functioning lymphatics are believed to reduce edema and to provide a transiting route for immune cells, but the extent at which the dermal lymphatic remodeling impacts lymphatic transport or the factors regulating these changes
Pier-Anne Lachance, Amy Hazen, Eva M Sevick-Muraca   +2 more
doaj   +1 more source