Results 11 to 20 of about 1,011,532 (393)

Renal lymphatic vessel dynamics

American Journal of Physiology-Renal Physiology, 2020
Similar to other organs, renal lymphatics remove excess fluid, solutes, and macromolecules from the renal interstitium. Given the kidney’s unique role in maintaining body fluid homeostasis, renal lymphatics may be critical in this process. However, little is known regarding the pathways involved in renal lymphatic vessel function, and there are no ...
Haichun Yang, Haichun Yang, Jianyong Zhong, Jianyong Zhong, Michele M Salzman, Valentina Kon, Elaine L. Shelton, Elaine L. Shelton   +7 more
openaire   +5 more sources

High lymphatic vessel density and presence of lymphovascular invasion both predict poor prognosis in breast cancer

BMC Cancer, 2017
Background Lymphatic vessel density and lymphovascular invasion are commonly assessed to identify the clinicopathological outcomes in breast cancer. However, the prognostic values of them on patients’ survival are still uncertain.
Song Zhang, Dong Zhang, Mingfu Gong, Li Wen, Cuiwei Liao, Liguang Zou   +5 more
doaj   +2 more sources

Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. [PDF]

Nature Communications, 2015
The lymphatic system maintains tissue fluid balance, and dysfunction of lymphatic vessels and valves causes human lymphedema syndromes. Yet, our knowledge of the molecular mechanisms underlying lymphatic vessel development is still limited. Here, we show
Adams, R.H., Agalarov, Y., Bibb, J.A., Demir, C.S., Hager, B., Kiefer, F., Liebl, J., Miura, N., Moser, M., Petrova, T.V., Vollmar, A.M., Zahler, S., Zhang, S.   +12 more
core   +3 more sources

Blood and Lymphatic Vessel Formation [PDF]

Cold Spring Harbor Perspectives in Biology, 2015
Blood and lymphatic vessels deliver oxygen and nutrients, remove waste and CO2, and regulate interstitial pressure in tissues and organs. These vessels begin life early in embryogenesis using transcription factors and signaling pathways that regulate differentiation, morphogenesis, and proliferation.
Kathleen M. Caron, Victoria L. Bautch
openaire   +3 more sources

Biomechanical control of lymphatic vessel physiology and functions. [PDF]

Cell Mol Immunol, 2023
The ever-growing research on lymphatic biology has clearly identified lymphatic vessels as key players that maintain human health through their functional roles in tissue fluid homeostasis, immunosurveillance, lipid metabolism and inflammation.
Angeli V, Lim HY.
europepmc   +2 more sources

The Underlying Role of the Glymphatic System and Meningeal Lymphatic Vessels in Cerebral Small Vessel Disease

Biomolecules, 2022
There is a growing prevalence of vascular cognitive impairment (VCI) worldwide, and most research has suggested that cerebral small vessel disease (CSVD) is the main contributor to VCI. Several potential physiopathologic mechanisms have been proven to be
Yu-Syuan Tian, Mengxi Zhao, Yiyi Chen, Mo Yang, Yilong Wang   +4 more
semanticscholar   +1 more source

Lymphatic Collecting Vessel: New Perspectives on Mechanisms of Contractile Regulation and Potential Lymphatic Contractile Pathways to Target in Obesity and Metabolic Diseases

Frontiers in Pharmacology, 2022
Obesity and metabolic syndrome pose a significant risk for developing cardiovascular disease and remain a critical healthcare challenge. Given the lymphatic system’s role as a nexus for lipid absorption, immune cell trafficking, interstitial fluid and ...
Yang Lee, Scott D. Zawieja, Mariappan Muthuchamy   +2 more
doaj   +1 more source

Investigating lymphangiogenesis in vitro and in vivo using engineered human lymphatic vessel networks

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Lymphatic vessel networks are important for various biological processes; thus, incorporating them into engineered constructs can have both research and clinical implications.
S. Landau, A. Newman, Shlomit Edri, I. Michael, S. Ben-Shaul, Y. Shandalov, Tom Ben-Arye, P. Kaur, M. Zheng, S. Levenberg   +9 more
semanticscholar   +1 more source

Lymphatic Vessel Invasion in Routine Pathology Reports of Papillary Thyroid Cancer

Frontiers in Medicine, 2022
PurposeIt is not mandatory to report lymphatic vessel invasion in pathology reports of papillary thyroid cancer (PTC) according to the current Union for International Cancer Control (UICC) TNM (tumor, nodes, and metastases) classification. However, there
Costanza Chiapponi, Hakan Alakus, Matthias Schmidt, Michael Faust, Christiane J. Bruns, Reinhard Büttner, Marie-Lisa Eich, Anne M. Schultheis   +7 more
doaj   +1 more source

Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart

Development, 2020
Macrophages are components of the innate immune system with key roles in tissue inflammation and repair. It is now evident that macrophages also support organogenesis, but few studies have characterized their identity, ontogeny and function during heart ...
T. Cahill, Xin Sun, Christophe Ravaud, Cristina Villa del Campo, K. Klaourakis, Irina-Elena Lupu, Allegra M. Lord, Cathy Browne, S. Jacobsen, D. Greaves, D. Jackson, S. Cowley, W. James, R. Choudhury, J. Vieira, P. Riley   +15 more
semanticscholar   +1 more source