Results 21 to 30 of about 80,361 (351)

Lymphatic vessel: Origin, heterogeneity, biological functions and therapeutic targets [PDF]

open access: yesSignal Transduction and Targeted Therapy
Lymphatic vessels, comprising the secondary circulatory system in human body, play a multifaceted role in maintaining homeostasis among various tissues and organs.
Zhaoliang Hu   +7 more
doaj   +2 more sources

Spatio-temporal Models of Lymphangiogenesis in Wound Healing [PDF]

open access: yesarXiv, 2016
Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries.
A Bianchi   +117 more
core   +2 more sources

Lymphatic vessel network injury reduces local tumor control despite preservation of the tumor-draining lymph node [PDF]

open access: yesScientific Reports
The lymphatic system plays complex, often contradictory, roles in many cancers, including melanoma; these roles include contributions to tumor cell metastasis and immunosuppression in the tumor microenvironment as well as generation of antitumor immunity.
Lauren N. Liebman   +6 more
doaj   +2 more sources

Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival [PDF]

open access: yesBMC Cancer, 2001
Background We assessed the nm23-H1 gene product expression and its relationship with lymphatic and blood vessel invasion in patients with esophageal squamous cell carcinoma.
Shimizu Tetsuya   +7 more
doaj   +5 more sources

How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis? [PDF]

open access: yesWorld Journal of Surgical Oncology, 2007
Background Lymphatic vessels are major routes for metastasis in head and neck squamous cell carcinoma (HNSCC), but lymphatic endothelial cells (LECs) are difficult to recognize in tumor histological sections. D2-40 stains podoplanin, a molecule expressed
Mercante Ana   +7 more
doaj   +4 more sources

Comparison of normal hindlimb lymphatic systems in rats with detours present after lymphatic flow blockage.

open access: yesPLoS ONE, 2021
In the present study, we aimed to identify the normal hindlimb lymphatic systems in rats and compare them with the detours after lymphatic flow blockage.
Yuiko Suzuki   +4 more
doaj   +1 more source

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Microenvironmental signals produced during development or inflammation stimulate lymphatic endothelial cells to undergo lymphangiogenesis, in which they sprout, proliferate, and migrate to expand the vascular network.
Delayna Paulson   +10 more
doaj   +1 more source

Lymphatic Collecting Vessel: New Perspectives on Mechanisms of Contractile Regulation and Potential Lymphatic Contractile Pathways to Target in Obesity and Metabolic Diseases

open access: yesFrontiers in Pharmacology, 2022
Obesity and metabolic syndrome pose a significant risk for developing cardiovascular disease and remain a critical healthcare challenge. Given the lymphatic system’s role as a nexus for lipid absorption, immune cell trafficking, interstitial fluid and ...
Yang Lee   +2 more
doaj   +1 more source

Lymphatic vascular response to acute inflammation. [PDF]

open access: yesPLoS ONE, 2013
During acute inflammation, functioning lymphatics are believed to reduce edema and to provide a transiting route for immune cells, but the extent at which the dermal lymphatic remodeling impacts lymphatic transport or the factors regulating these changes
Pier-Anne Lachance   +2 more
doaj   +1 more source

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