Results 21 to 30 of about 50,153 (264)

Clinical implications of increased lymph vessel density in the lymphatic metastasis of early-stage invasive cervical carcinoma: a clinical immunohistochemical method study

BMC Cancer, 2009
Background Cervical cancer is the most common malignant gynecological cancer, and lymphatic metastasis can occur in the early stage of tumor growth. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a marker for lymphatic endothelium, provides
Yu Hao, Zhang Shi-qian, Zhang Lin-lin
doaj   +1 more source

Protocol for in vivo and in vitro study of lymphatic valve formation driven by shear stress signaling pathway

STAR Protocols, 2023
Summary: Here we detail a protocol for the isolation and processing of lymphatic enriched tissue of mouse models for the purpose of immunostaining and quantification of lymphatic valves, vessel length, and vessel diameter.
Richa Banerjee, Luz A. Knauer, Ying Yang
doaj   +1 more source

The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma

Journal of Experimental & Clinical Cancer Research, 2009
Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Zhang Renhua, Zhang Shiqian, Yu Hao, Zhang Linlin   +3 more
doaj   +1 more source

Microanatomical organization of hepatic venous lymphatic system in humans.

PLoS ONE, 2023
Lymphatic fluid drains from the liver via the periportal lymphatic, hepatic venous lymphatic, and superficial lymphatic systems. We performed a postmortem study to clarify the three-dimensional structure and flow dynamics of the human hepatic venous ...
Kotaro Umemura, Hiroshi Shimoda, Keinosuke Ishido, Norihisa Kimura, Taiichi Wakiya, Takuji Kagiya, Kentaro Sato, Yuto Mitsuhashi, Seiji Watanabe, Hirokazu Narita, Tomohiro Chiba, Kenichi Hakamada   +11 more
doaj   +2 more sources

Confocal Imaging: Blood and Lymphatic Capillaries

The Scientific World Journal, 2006
Traditional imaging techniques are quite limited for the study of the relationship between blood vessels and lymphatic vessels. Therefore, a new imaging technique is required based on blood vessel and lymphatic endothelial-specific molecular markers.
Yingjie Cui
doaj   +1 more source

Lymphatic Vessels and Their Surroundings: How Local Physical Factors Affect Lymph Flow

Biology, 2020
Lymphatic vessels drain and propel lymph by exploiting external forces that surrounding tissues exert upon vessel walls (extrinsic mechanism) and by using active, rhythmic contractions of lymphatic muscle cells embedded in the vessel wall of collecting ...
Eleonora Solari, Cristiana Marcozzi, Daniela Negrini, Andrea Moriondo   +3 more
doaj   +1 more source

Solute Transport across the Lymphatic Vasculature in a Soft Skin Tissue

Biology, 2023
Convective transport of drug solutes in biological tissues is regulated by the interstitial fluid pressure, which plays a crucial role in drug absorption into the lymphatic system through the subcutaneous (SC) injection.
Dingding Han, Ziyang Huang, Ehsan Rahimi, Arezoo M. Ardekani   +3 more
doaj   +1 more source

Digging deeper into lymphatic vessel formation in vitro and in vivo

BMC Cell Biology, 2011
Background Abnormal lymphatic vessel formation (lymphangiogenesis) is associated with different pathologies such as cancer, lymphedema, psoriasis and graft rejection.
Thiry Marc, Foidart Jean-Michel, Lenoir Bénédicte, Maillard Catherine, Lamaye Françoise, Paupert Jenny, Erpicum Charlotte, Bruyère Françoise, Detry Benoit, Noël Agnès   +9 more
doaj   +1 more source

Lymphangiogenesis Guidance Mechanisms and Therapeutic Implications in Pathological States of the Cornea

Cells, 2023
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection.
Mehul Patnam, Sunil R. Dommaraju, Faisal Masood, Paula Herbst, Jin-Hong Chang, Wen-Yang Hu, Mark I. Rosenblatt, Dimitri T. Azar   +7 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source