Results 21 to 30 of about 87,743 (301)

Objective assessment of blood and lymphatic vessel invasion and association with macrophage infiltration in cutaneous melanoma [PDF]

open access: yes, 2011
The aims of this study were to investigate the role of vascular invasion (blood and lymphatic), vessel density and the presence of tumour-associated macrophages as prognostic markers in 202 cutaneous melanoma patients.
Cook, Martin   +12 more
core   +3 more sources

Primary Head and Neck Tumour-Derived Fibroblasts Promote Lymphangiogenesis in a Lymphatic Organotypic Co-culture Model

open access: yesEBioMedicine, 2021
Background: In head and neck cancer, intratumour lymphatic density and tumour lymphangiogenesis have been correlated with lymphatic metastasis, making lymphangiogenesis a promising therapeutic target.
Karina M. Lugo-Cintrón   +8 more
doaj   +1 more source

Chronic high-fat diet impairs collecting lymphatic vessel function in mice.

open access: yesPLoS ONE, 2014
Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction.
Katrin S Blum   +7 more
doaj   +1 more source

High relative density of lymphatic vessels predicts poor survival in tongue squamous cell carcinoma [PDF]

open access: yes, 2016
Tongue cancer has a poor prognosis due to its early metastasis via lymphatic vessels. The present study aimed at evaluating lymphatic vessel density, relative density of lymphatic vessel, and diameter of lymphatic vessels and its predictive role in ...
Huhtala, Heini   +8 more
core   +1 more source

Three-Dimensional In Vitro Lymphangiogenesis Model in Tumor Microenvironment

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Lymphangiogenesis is a stage of new lymphatic vessel formation in development and pathology, such as inflammation and tumor metastasis. Physiologically relevant models of lymphatic vessels have been in demand because studies on lymphatic vessels are ...
Youngkyu Cho   +9 more
doaj   +1 more source

Lymphangiography to treat postoperative lymphatic leakage: a technical review. [PDF]

open access: yes, 2014
In addition to imaging the lymphatics and detecting various types of lymphatic leakage, lymphangiography is a therapeutic option for patients with chylothorax, chylous ascites, and lymphatic fistula.
Kim, Soo Hwan   +5 more
core   +1 more source

MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis [PDF]

open access: yes, 2016
Lymphangiogensis is involved in various pathological conditions, such as arthritis and cancer metastasis. Although many factors have been identified to stimulate lymphatic vessel growth, little is known about lymphangiogenesis inhibitors.
Cao, R   +5 more
core   +1 more source

High lymphatic vessel density and presence of lymphovascular invasion both predict poor prognosis in breast cancer

open access: yesBMC Cancer, 2017
Background Lymphatic vessel density and lymphovascular invasion are commonly assessed to identify the clinicopathological outcomes in breast cancer. However, the prognostic values of them on patients’ survival are still uncertain.
Song Zhang   +5 more
doaj   +1 more source

Protocol for in vivo and in vitro study of lymphatic valve formation driven by shear stress signaling pathway

open access: yesSTAR Protocols, 2023
Summary: Here we detail a protocol for the isolation and processing of lymphatic enriched tissue of mouse models for the purpose of immunostaining and quantification of lymphatic valves, vessel length, and vessel diameter.
Richa Banerjee, Luz A. Knauer, Ying Yang
doaj   +1 more source

Microanatomical organization of hepatic venous lymphatic system in humans.

open access: yesPLoS ONE, 2023
Lymphatic fluid drains from the liver via the periportal lymphatic, hepatic venous lymphatic, and superficial lymphatic systems. We performed a postmortem study to clarify the three-dimensional structure and flow dynamics of the human hepatic venous ...
Kotaro Umemura   +11 more
doaj   +2 more sources

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