Results 51 to 60 of about 923,689 (313)
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Absence of lymphatic vessels in term placenta [PDF]
BMC Pregnancy and Childbirth, 2020 Abstract Background There has been debate about the existence of lymphatic vessels in placenta. Lymphatic endothelial cell (LEC) markers such as LYVE-1 and podoplanin/D2–40 have been found, although PROX1 has not been detected. The most reliable marker for LECs is the double staining for CD31 and PROX1, which has not been performed yet.
Jürgen Becker +5 more
openaire +5 more sources
Lymphatic Mapping for LVA with Noncontrast Lymphatic Ultrasound: How We Do It
Plastic and Reconstructive Surgery, Global OpenSummary:. Recently, lymphatic ultrasonography has received increasing attention. Although there are several reports on contrast-enhanced lymphatic ultrasound as a preoperative examination for lymphaticovenous anastomosis (LVA), we have been reporting the
Hisako Hara, MD, PhD +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen +6 more
wiley +1 more source
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 147-156, January 2023., 2023 This study indicated that LN of both the CA and SMA systems should be dissected in patients with Pb‐PDAC. However, only those around the SPA and splenic hilus should be dissected routinely in those with Pt‐PDAC. Abstract Introduction In patients with pancreatic ductal adenocarcinoma (PDAC) in the pancreatic body (Pb) and tail (Pt), the appropriate area
Yuki Matsui +8 more
wiley +1 more source
Lymphatic Vessels in Inflammation
Journal of Clinical & Cellular Immunology, 2014 Lymphatic vessels are important for tissue fluid homeostasis and for the uptake of dietary lipids in the intestine. Moreover, lymphatic vessels are intimately linked with induction of the immune response, as they transport antigen, inflammatory mediators, and leukocytes from peripheral tissues to draining lymph nodes (dLNs).
Martina Vranova, Cornelia Halin
openaire +2 more sources
Inhibiting corneal transplantation rejection via lymphatic vessel ligation in a novel murine model
Scientific ReportsThe lymphatic system is a crucial contributor to allograft rejection after corneal transplantation. However, no surgical procedures for the central pathway where conjunctival lymphatic vessels converge have been investigated.
Ami Igarashi +4 more
doaj +1 more source
Hydrogen sulfide donor activates AKT-eNOS signaling and promotes lymphatic vessel formation.
PLoS ONE, 2023 The lymphatic network is pivotal for various physiological functions in the human body. Accumulated evidence supports the role of therapeutic lymphangiogenesis in the treatment of several pathologies.
Ravi Varma Aithabathula +7 more
doaj +1 more source
Pump efficacy in a fluid-structure interaction model of a chain of contracting lymphangions [PDF]
arXiv, 2020 The transport of lymph through the lymphatic vasculature is the mechanism for returning excess interstitial fluid to the circulatory system, and it is essential for fluid homeostasis. Collecting lymphatic vessels comprise a significant portion of the lymphatic vasculature and are divided by valves into contractile segments known as lymphangions ...
arxiv