Results 51 to 60 of about 968,485 (355)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Lymphatic Endothelial Markers and Tumor Lymphangiogenesis Assessment in Human Breast Cancer

open access: yesDiagnostics, 2021
Metastasis via lymphatic vessels or blood vessels is the leading cause of death for breast cancer, and lymphangiogenesis and angiogenesis are critical prerequisites for the tumor invasion–metastasis cascade.
Jia-Mei Chen   +5 more
doaj   +1 more source

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation

open access: yesCirculation Research, 2017
Rationale: Lymphatic vessel formation and function constitutes a physiologically and pathophysiologically important process, but its genetic control is not well understood.
Terhi Karpanen   +12 more
semanticscholar   +1 more source

Lymphatic vessels in health and disease [PDF]

open access: yesWIREs Systems Biology and Medicine, 2012
AbstractThe lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling occur primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth.
Lance L. Munn   +3 more
openaire   +3 more sources

Absence of lymphatic vessels in term placenta [PDF]

open access: yesBMC Pregnancy and Childbirth, 2020
Abstract Background There has been debate about the existence of lymphatic vessels in placenta. Lymphatic endothelial cell (LEC) markers such as LYVE-1 and podoplanin/D2–40 have been found, although PROX1 has not been detected. The most reliable marker for LECs is the double staining for CD31 and PROX1, which has not been performed yet.
Jürgen Becker   +5 more
openaire   +5 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Lymphatic Mapping for LVA with Noncontrast Lymphatic Ultrasound: How We Do It

open access: yesPlastic and Reconstructive Surgery, Global Open
Summary:. Recently, lymphatic ultrasonography has received increasing attention. Although there are several reports on contrast-enhanced lymphatic ultrasound as a preoperative examination for lymphaticovenous anastomosis (LVA), we have been reporting the
Hisako Hara, MD, PhD   +4 more
doaj   +1 more source

Pump efficacy in a fluid-structure interaction model of a chain of contracting lymphangions [PDF]

open access: yesarXiv, 2020
The transport of lymph through the lymphatic vasculature is the mechanism for returning excess interstitial fluid to the circulatory system, and it is essential for fluid homeostasis. Collecting lymphatic vessels comprise a significant portion of the lymphatic vasculature and are divided by valves into contractile segments known as lymphangions ...
arxiv  

Home - About - Disclaimer - Privacy