Results 231 to 240 of about 509,257 (301)

Sodium-Directed Crosstalk Between Immune Cells and Lymphatic Vessels. [PDF]

open access: yesCurr Hypertens Rep
Ahmad T   +4 more
europepmc   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama   +2 more
wiley   +1 more source

Detection of Efferent Lymphatic Vessels Using Gamma Probe Guidance for Efferent Lymphatic Vessel Anastomosis. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Tsuchiya M   +5 more
europepmc   +1 more source

Isolated Cephalic Perfusion via Aortic Occlusion for Cervicofacial Simulation: Validation of a High‐Fidelity Cadaveric Model

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective High‐fidelity simulation may improve surgical training in head and neck surgery, yet validated perfused cadaveric models remain scarce. We evaluated the face, content, and construct validity of a perfused cadaveric model using isolated cephalic perfusion for cervicofacial surgical simulation. Study Design Prospective validation study
Victor Benvegnu   +14 more
wiley   +1 more source

Beyond a single ratio: an adaptable deep learning approach to analyze the prognostic value of TSP distribution in ovarian cancer

open access: yesThe Journal of Pathology, EarlyView.
Abstract The tumor–stroma percentage (TSP) has been proposed as a prognostic factor in ovarian cancer. When assessed manually by pathologists, the TSP can be subject to significant inter‐rater variability. Automated methods for TSP determination have recently been developed.
Daniel Firmbach   +11 more
wiley   +1 more source

GH Alters Lymphatic Vessels in Female Mice and STAT5 Phosphorylation in Human Lymphatic Endothelial Cells.

open access: yesEndocrinology
Walsh C   +11 more
europepmc   +1 more source

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