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Obesity-Associated Conditions Hinder Solute Drainage Function of Engineered Human Lymphatic Vessels. [PDF]

Cell Mol Bioeng
Seibel AJ, Frosti CL, Tlemçani AR, Lahiri N, Brammer-DePuy JA, Layne MD, Tien J.   +6 more
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Lymphatic vessels in cancer

Physiological Reviews, 2022
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph nodes that are present in almost every tissue of the human body, acts as an essential transport system for fluids, biomolecules, and cells between peripheral tissues and the central circulation. Consequently, it is required for normal body physiology but is also
Lothar C. Dieterich, Carlotta Tacconi, Luca Ducoli, Michael Detmar   +3 more
openaire   +2 more sources

Dendritic-Cell Trafficking to Lymph Nodes Through Lymphatic Vessels

Nature Reviews Immunology, 2005
Antigen-presenting dendritic cells often acquire foreign antigens in peripheral tissues such as the skin. Optimal encounter with naive T cells for the presentation of these antigens requires that the dendritic cells migrate to draining lymph nodes ...
Melody Swartz, Gwendalyn J. Randolph, Veronique Angeli   +2 more
exaly   +2 more sources

Permeability of lymphatic vessels

American Journal of Physiology-Legacy Content, 1962
Substances of various molecular sizes were infused through leg or mesenteric lymphatics of anesthetized dogs and their concentrations were followed in thoracic duct lymph and plasma for the subsequent 2 1/2 hr. An isolated in vivo popliteal lymph node preparation was also perfused with some of the same substances. Small molecules were found to diffuse
H S, MAYERSON, R M, PATTERSON, A, McKEE, S J, LEBRIE, P, MAYERSON   +4 more
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Biomechanics of a Lymphatic Vessel

Blood Vessels, 2008
The principles of mechanics and the current notions of lymphatic physiology are integrated into a simple mathematical model of a lymphatic vessel which establishes a theoretical base for lymph propulsion in the lymphatic system. The model specifically considers the active and passive contractilities of the lymphatics.
N P, Reddy, T A, Krouskop, P H, Newell
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Leukocyte Trafficking in Lymphatic Vessels

Cold Spring Harbor Perspectives in Medicine, 2022
To ensure proper immune function, most leukocytes constantly move within tissues or between them using the blood and lymphatic vessels as transport routes. While afferent lymphatic vessels transfer leukocytes from peripheral tissues to draining lymph nodes (dLNs), efferent lymphatics return lymphocytes from LNs back into the blood vascular circulation.
Aline, Bauer, Hazal, Tatliadim, Cornelia, Halin   +2 more
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The Demonstration of Lymphatic Vessels.

Lancet, The, 1955
exaly   +3 more sources

Microsurgical Lymphatic Vessel Transplantation

Journal of Reconstructive Microsurgery, 2015
Lymphedema often arises after a regional interruption during cancer treatment, for example after lymph node resection the axilla or the groin. Lymphatic vessels as vascular grafts may overcome these lymphatic gaps.Experiments in rats and dogs were performed for developing this method.
Ruediger G H, Baumeister, Weiss, Mayo, Mike, Notohamiprodjo, Jens, Wallmichrath, Stephanie, Springer, Andreas, Frick   +5 more
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Lymphatic Vessel Activation in Cancer

Annals of the New York Academy of Sciences, 2002
Abstract: Metastasis of most cancers occurs primarily through the lymphatic system, and the extent of lymph node involvement is the most important prognostic indicator. While the importance of the lymphatic system as a pathway for metastasis has been well recognized, there is very little information available about the mechanisms by which tumor cells ...
Melanie, Cassella, Mihaela, Skobe
openaire   +2 more sources