Results 81 to 90 of about 50,895 (299)
The Role of the Lymphatic System in Cholesterol Transport
Frontiers in Pharmacology, 2015 Reverse cholesterol transport (RCT) is the pathway for removal of peripheral tissue cholesterol and involves transport of cholesterol back to liver for excretion, starting from cellular cholesterol efflux facilitated by lipid-free apolipoprotein A1 ...
Li-Hao eHuang +2 more
doaj +1 more source
Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source
Advanced Science, EarlyView.Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Expression of lymphatic markers in the adult rat spinal cord
Frontiers in Cellular Neuroscience, 2016 Under physiological conditions, lymphatic vessels are thought to be absent from the central nervous system (CNS), although they are widely distributed within the rest of the body. Recent work in the eye, i.e.
Alexandra eKaser-Eichberger +18 more
doaj +1 more source
VEGF-D(ilated) lymphatics as gateways for metastasis [PDF]
, 2012 VEGF-C and VEGF-D have been implicated in lymphatic metastasis, mainly as inducers of newintra/peritumoural capillary lymphatics. In this issue of Cancer Cell, Stacker and colleagueschallenge this notion and demonstrate that tumour-derived VEGF-D ...
Rak, Janusz
core +1 more source
Advanced Science, EarlyView.A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao +11 more
wiley +1 more source
CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Advanced Science, EarlyView.Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
Immunofluorescence studies of initial lymphatics and epifascial lymphatic collectors.
, 2016 A-C) Staining of initial lymphatics with the antibodies Prox-1 (A, B) and vimentin (A, C). Vimentin is expressed in initial lymphatics. L, lumen of the lymphatics. Arrowheads point to the nuclei of LECs. Bar = 25μm.
Viktoria Hasselhof (3232911) +7 more
core +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source