Results 91 to 100 of about 50,895 (299)

PROSTACYCLIN SYNTHESIS IN HUMAN LYMPHATICS

, 2017
The ability of human lymphatics to generate prostacyclinin important amounts (4.5 ± 2.1 pg/mg/min)is described. The prostacyclin produced, exhib its thesame properties as reported for arterial and venoustissue. No age and sex difference could be observed.
Sinzinger, H, Oppolzer, R, Silberbauer, K, Mannheimer, E   +3 more
core  

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Mesenteric Lymphatic Alterations Observed During DSS Induced Intestinal Inflammation Are Driven in a TLR4-PAMP/DAMP Discriminative Manner

Frontiers in Immunology, 2019
Background: Inflammatory bowel disease (IBD) is characterized by both acute and chronic phase inflammation of the gastro-intestinal (GI) tract that affect a large and growing number of people worldwide with little to no effective treatments.
Matthew Stephens, Shan Liao, Pierre-Yves von der Weid   +2 more
doaj   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

Advanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger, Matthew R. DeWitt, Carly M. Van Wagoner, Claire A. Conarroe, Charles C. Funk, Aaron B. Streit, AeRyon Kim, Richard J. Price, Timothy N. J. Bullock   +8 more
wiley   +1 more source

Discussion on “Lymphatism” [PDF]

Proceedings of the Royal Society of Medicine, 1910
  +11 more sources

Role of inducible nitric oxide (iNOS) and nitrosative stress in regulating sex differences in secondary lymphedema

Frontiers in Physiology
Secondary lymphedema is a common complication following surgical treatment of solid tumors. Although more prevalent in women due to higher breast cancer rates, men also develop lymphedema, often with more severe manifestations.
Adana-Christine Campbell, Kevin G. Kuonqui, Gopika Ashokan, Jonathan Rubin, Jinyeon Shin, Bracha L. Pollack, Arielle Roberts, Ananta Sarker, Hyeung Ju Park, Raghu P. Kataru, Andrea V. Barrio, Babak J. Mehrara   +11 more
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Evaluation of the Structural and Functional Dynamics of Extracellular Matrix of the Skin and Histochemical Characterization of the Dermal Interstitium

National Board of Examinations Journal of Medical Sciences
Introduction: Skin is the largest organ in the body consists of three layers, epidermis, dermis and hypodermis. Skin along with its accessories like nails, hair follicles, sweat glands and sebaceous glands forms the integumentary system.
Sridhar Krishnamoorthy, Rajan Thangarasu, Jawahar Ramasamy, Kalaivannan J, Ilankathir Sridharan   +4 more
doaj   +1 more source

Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma

OncoImmunology, 2018
Increased density of tumor-associated lymphatic vessels correlates with poor patient survival in melanoma and other cancers, yet lymphatic drainage is essential for initiating an immune response.
Natacha Bordry, Maria A. S. Broggi, Kaat de Jonge, Karin Schaeuble, Philippe O. Gannon, Periklis G. Foukas, Esther Danenberg, Emanuela Romano, Petra Baumgaertner, Manuel Fankhauser, Noémie Wald, Laurène Cagnon, Samia Abed-Maillard, Hélène Maby-El Hajjami, Timothy Murray, Kalliopi Ioannidou, Igor Letovanec, Pu Yan, Olivier Michielin, Maurice Matter, Melody A. Swartz, Daniel E. Speiser   +21 more
doaj   +1 more source

Impact of Lymphangiogenesis on Cardiac Remodeling After Ischemia and Reperfusion Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Lymphatic vessels interconnect with blood vessels to form an elaborate system that aids in the control of tissue pressure and edema formation. Although the lymphatic system has been known to exist in a heart, little is known about the role the
Yuuki Shimizu, Rohini Polavarapu, Kattri‐Liis Eskla, Yvanna Pantner, Chad K. Nicholson, Masakazu Ishii, Daniel Brunnhoelzl, Rohit Mauria, Ahsan Husain, Nawazish Naqvi, Toyoaki Murohara, John W. Calvert   +11 more
doaj   +1 more source