Road traffic pollution and childhood leukemia: a nationwide case-control study in Italy [PDF]
Background The association of childhood leukemia with traffic pollution was considered in a number of studies from 1989 onwards, with results not entirely consistent and little information regarding subtypes.
Alberto Salvan+79 more
core +1 more source
ACUTE LYMPHOBLASTIC LEUKEMIAS AND LYMPHOMAS OF CHILDHOOD WITH T CELL ORIGIN: CLINICAL FEATURES AND PROGNOSIS [PDF]
John H. Kersey+3 more
openalex +1 more source
ABSTRACT Introduction Developing targeted therapies with manageable toxicities remains a high priority for pediatric cancer. We sought to determine the recommended Phase 2 dose (RP2D) and evaluate the antitumor activity of lenvatinib+everolimus in children/young adults with select recurrent/refractory solid tumors.
Filemon S. Dela Cruz+20 more
wiley +1 more source
Understanding the role of B-cells in CAR T-cell therapy in leukemia through a mathematical model [PDF]
Chimeric Antigen Receptor T (CAR-T) cell therapy has been proven to be successful against different leukaemias and lymphomas. This paper makes an analytical and numerical study of a mathematical model describing the competition of CAR-T, leukaemias tumor and B cells.
arxiv
Cell surface characterization of malignant T cells from lymphoblastic lymphoma using monoclonal antibodies: evidence for phenotypic differences between malignant T cells from patients with acute lymphoblastic leukemia and lymphoblastic lymphoma [PDF]
A Bernard+11 more
openalex +1 more source
Late Mortality Among Survivors of Childhood Cancer in Canada: A Retrospective Cohort Study
ABSTRACT Background Children with cancer face an increased risk of complications and death beyond the 5‐year survival mark. National surveillance efforts facilitate the systematic tracking of long‐term health outcomes, including treatment‐related complications and late mortality, among childhood cancer survivors.
Katherine McKenzie+5 more
wiley +1 more source
Terminal deoxynucleotidyl transferase-containing cells in peripheral blood: implications for the surveillance of patients with lymphoblastic leukemia or lymphoma in remission [PDF]
TW Froehlich+4 more
openalex +1 more source
ABSTRACT High‐dose methotrexate dosage and infusion durations differ across treatment protocols for pediatric leukemia, lymphoma, and osteosarcoma. Supportive care interventions are dependent on a patient's elimination of methotrexate (MTX). Therefore, it is important to establish the expected MTX elimination across protocols.
Zachary L. Taylor+11 more
wiley +1 more source
Molecular mechanisms in haematological malignancies [PDF]
Haematopoiesis requires the constant production of large numbers of peripheral blood cells. This process is under tight control of transcription factor networks as well as cytokines, growth factors and hormones.
Avellino, Roberto+2 more
core
Reactive histiocytosis in acute lymphoblastic leukemia and non-hodgkin' s lymphoma [PDF]
Der‐Cherng Liang+2 more
openalex +1 more source