Results 221 to 230 of about 491,626 (323)

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu, Xiao‐Mei Wu, Yan Hu, Xiao‐Lan Bian, Ya‐Qin Wang, Qiong‐Ni Zhu   +5 more
wiley   +1 more source

Secondary neoplasms in survivors of pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma: a single-center, retrospective study. [PDF]

Front Pediatr
Ushida E, Toyoda H, Kohso A, Okumura Y, Niwa K, Ito T, Morimoto M, Hanaki R, Amano K, Iwamoto S, Deguchi T, Hori H, Hirayama M.   +12 more
europepmc   +1 more source

A childhood chemotherapy protocol improves overall survival among adults with T-lymphoblastic lymphoma

, 2016
Meng-Yuan Zhu, Hua Wang, Chun-yu Huang, Zhong-Jun Xia, Xiao-qin Chen, Qi-rong Geng, Wei-da Wang, Liang Wang, Yue Lu   +8 more
openalex   +2 more sources

Venetoclax and Homoharringtonine‐Based Therapy Exhibited a Striking Response in Refractory/Relapsed Early T‐Cell Precursor Acute Lymphoblastic Leukemia

MedComm, Volume 6, Issue 12, December 2025.
Early T‐cell precursor acute lymphoblastic leukemia (ETP‐ALL) was an aggressive subtype of T‐ALL with an extremely poor prognosis. We demonstrated that the V‐HAG regimen (venetoclax, homoharringtonine, cytarabine, and G‐CSF) was highly effective in refractory/relapsed patients.
Xiang Zhang, Hongsheng Zhou, Liping Mao, Yinjun Lou, Lijing Shen, Ying Lu, Zhenfang Liu, Xiuzhen Tong, Aiping Zhang, Tingbo Liu, Na Zhang, Xingnong Ye, Juying Wei, Meihong Luo, Shaoyuan Wang, Qingxian Bai, Jian Hou, Qifa Liu, Hongyan Tong, Jie Jin, Wenjuan Yu   +20 more
wiley   +1 more source

Nelarabine for T-cell acute lymphoblastic leukaemia and T-cell lymphoblastic lymphoma. [PDF]

Aust Prescr
europepmc   +1 more source

Age and Sex Differences in the Prevalence of Specific Comorbidities among Patients with Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma at Diagnosis. [PDF]

Cancer Res Commun
Yang X, Mosha M, Bell D, Dean J, Mayer J, Amankwah EK.   +5 more
europepmc   +1 more source

A case of B-cell acute lymphoblastic lymphoma/leukemia with optic-nerve involvement as the first manifestation detected by 18 F-FDG PET/CT

Min Fan, Yong Liu, Chunyin Zhang, Jie Zhao   +3 more
openalex   +1 more source

Nanosensors in Leukemia Management: Pioneering Real‐Time Biomarker Detection for Precision Oncology

Nano Select, Volume 6, Issue 12, December 2025.
This review highlights pioneering nanosensors designed for real‐time leukemia biomarker detection, integrating advanced nanomaterials such as liposomes, polymeric nanoparticles and quantum dots. It examines electrochemical, optical and magnetic detection mechanisms, the applications across AML, ALL, CML, and CLL subtypes, and clinical translation ...
Hamed Soleimani Samarkhazan, Mohammad Navid Khaksari, Amirhossein Mirzazadeh, Mohammad Siavashi, Niloofar Pilehvari, Mohammad Hossein Mohammadi   +5 more
wiley   +1 more source

A Rare Case of T-cell Lymphoblastic Lymphoma: A Diagnostic Predicament. [PDF]

Cureus
Shil M, Srinivasan V, Vincent AA, Gaikwad T, Thomas D.   +4 more
europepmc   +1 more source

Mutation profiling in differential diagnosis between TdT‐positive high‐grade/large B‐cell lymphoma and B‐lymphoblastic leukaemia/lymphoma

The Journal of Pathology, Volume 267, Issue 4, Page 410-423, December 2025.
Abstract Terminal deoxynucleotidyl transferase (TdT) is occasionally expressed in large B‐cell lymphoma (LBCL), and this causes difficulty in differential diagnosis from B‐lymphoblastic leukaemia/lymphoma (B‐ALL/LBL). We reviewed 31 cases of TdT‐positive LBCL and B‐ALL/LBL, and their final diagnosis included 19 diffuse large/high‐grade BCLs with MYC ...
Maria‐Myrsini Tzioni, Francesco Cucco, Lívia Rásó‐Barnett, Zi Chen, Andrew Wotherspoon, Katrin S Kurz, Ewelina Madej, Jasmine Makker, Anna E Strazda, Fang Guo, Caoimhe Egan, Elizabeth Soilleux, Liz Hook, Laszlo Krenacs, Julia T Geyer, Camille Laurent, Luc Xerri, Lenaïg Mescam, Lukas Plank, Lise Mette Rahbek Gjerdrum, Nicolas Lopez‐Hisijos, Timothy Greiner, Joseph Khoury, Wolfram Klapper, Ilske Oschlies, Andreas Rosenwald, German Ott, Ming‐Qing Du   +27 more
wiley   +1 more source