Results 41 to 50 of about 491,626 (323)

Sinonasal Lymphoma Presenting as a Probable Sanctuary Site for Relapsed B Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature

Case Reports in Hematology, 2015
Sinonasal lymphoma is a non-Hodgkin lymphoma (NHL) representing 1.5% of all lymphomas. It presents as an unremitting ulceration with progressive destruction of midline sinonasal and surrounding structures. Poor prognosis warrants early treatment although
W. Y. Lim, R. Care, M. Lau, S. Chiruka, P. J. D. Dawes   +4 more
doaj   +1 more source

Differentiation of secondary involvement of the breast by lymphoreticular malignancy from fibroadenoma using ultrasound elastography: A report of two cases

Indian Journal of Radiology and Imaging, 2017
Extramedullary lymphoma infiltration of the breast by lymphoblastic lymphoma is very rare and most cases are of B-cell lineage; T-cell neoplasms represent less than 10% of all breast lymphomas.
Eren Abdulkadir, Ertan Gulhan, Sila Ulus
doaj   +1 more source

Phase 1 study to evaluate Crenigacestat (LY3039478) in combination with dexamethasone in patients with T‐cell acute lymphoblastic leukemia and lymphoma

Cancer, 2020
Deregulated Notch signaling is implicated in T‐cell acute lymphoblastic leukemia (T‐ALL)/T‐cell lymphoblastic lymphoma (T‐LBL). Crenigacestat (LY3039478) prevents cleavage of Notch proteins and may benefit patients with relapsed/refractory T‐ALL/T‐LBL.
G. Borthakur, G. Martinelli, E. Raffoux, P. Chevallier, J. Chromik, A. Lithio, Claire L Smith, E. Yuen, G. Oakley, K. Benhadji, D. DeAngelo   +10 more
semanticscholar   +1 more source

Treatment of young adults with Philadelphia‐negative acute lymphoblastic leukemia and lymphoblastic lymphoma: Hyper‐CVAD vs. pediatric‐inspired regimens

American journal of hematology/oncology, 2018
For young adults with acute lymphoblastic leukemia, pediatric‐based regimens are likely to provide the following when compared to hyper‐CVAD regimens: better disease control, less hospitalization time, diminished acute toxicities, decreased financial ...
S. Siegel, A. Advani, N. Seibel, Lori S Muffly, W. Stock, S. Luger, B. Shah, D. DeAngelo, D. Freyer, D. Douer, Rebecca H. Johnson, B. Hayes-Lattin, Mark A. Lewis, J. Jaboin, P. Coccia, A. Bleyer   +15 more
semanticscholar   +1 more source

Primary cutaneous B‐Cell lymphoblastic lymphoma presenting with solitary scalp mass in a female child: A case report and review of the literature

Clinical Case Reports, 2022
Lymphoblastic lymphoma is a group of non‐Hodgkin lymphomas that account for approximately 2% of all lymphomas. This is a report of a case of a young girl presenting with a solitary scalp mass which was resected.
Fatemeh Montazer, Alireza Sanei Motlagh, Ramtin Dastgir   +2 more
doaj   +1 more source

B Lymphoblastic Leukemia/Lymphoma with Recurrent Genetic Abnormalities

Definitions, 2020
precursor neoplasms which composed of B-lymphoblasts and characterized by the presence of recurrent genetic abnormalities.

semanticscholar   +1 more source

Rapid Progression of Mediastinal Tumor within a Few Days: A Case Report of T Cell Lymphoblastic Lymphoma

대한영상의학회지, 2016
T-cell lymphoblastic lymphoma is a highly aggressive tumor derived from lymphocyte of the thymus, which accounts for 2% of non-Hodgkin's lymphoma. The disease occurs most commonly in adolescent and young adult males.
Tae Ran Ahn, Young Kyung Lee, Hyun Jung Jun, Eun Ah Jung, Jin Sung Son   +4 more
doaj   +1 more source

Myeloid Sarcoma: A Mediastinal Masquerader

Journal of Medical Sciences and Health, 2023
Mediastinal Myeloid Sarcoma is a rare entity. Here we present a case of a 28-year-old gentleman, who first presented with a mediastinal mass and was clinically considered lymphoblastic lymphoma.
Jocelyn Sara Paul, Jahnavi Gandhi, Jyoti Sawhney, Trupti Patel, Priti Trivedi   +4 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin’s lymphoma and T-cell non-Hodgkin’s lymphoma

Haematologica, 2011
We recently reported deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia. Functional analyses confirmed that PTPN2 acts as classical tumor suppressor repressing the proliferation of T cells, in part through ...
Maria Kleppe, Thomas Tousseyn, Eva Geissinger, Zeynep Kalender Atak, Stein Aerts, Andreas Rosenwald, Iwona Wlodarska, Jan Cools   +7 more
doaj   +1 more source