Results 91 to 100 of about 506,913 (207)

Platelet-Derived Soluble CD40L and Its Impact on Immune Modulation and Anti-IL6R Antibody Treatment Outcome in Rheumatoid Arthritis

Cells
Background: Platelets (PLTs) from healthy donors (HD) modulate T lymphocyte responses but PLTs from rheumatoid arthritis (RA) patients contribute to persistent systemic inflammation.
Carlos Zamora, Cesar Diaz-Torne, Maria Angels Ortiz, Patricia Moya, Hye Sang Park, Concepció Pitarch, Elisabet Cantó, Ruben Osuna-Gomez, Maria Mulet, Maisa Garcia-Arguinzonis, Diego Collado, Hector Corominas, Silvia Vidal   +12 more
doaj   +1 more source

IL-6 and PD-1 antibody blockade combination therapy regulate inflammation and T lymphocyte apoptosis in murine model of sepsis

BMC Immunology
Background Interleukin-6 (IL-6) plays a central role in sepsis-induced cytokine storm involving immune hyperactivation and early neutrophil activation. Programmed death protein-1 (PD-1) is associated with sepsis-induced immunosuppression and lymphocyte ...
Song I Lee, Na Young Kim, Chaeuk Chung, Dongil Park, Da Hyun Kang, Duk Ki Kim, Min-Kyung Yeo, Pureum Sun, Jeong Eun Lee   +8 more
doaj   +1 more source

Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. [PDF]

, 2005
Lipid raft membrane compartmentalization and membrane-associated guanylate kinase (MAGUK) family molecular scaffolds function in establishing cell polarity and organizing signal transducers within epithelial cell junctions and neuronal synapses. Here, we
Miceli, M Carrie, Patel, Viresh, Round, June L, Schoenberger, Stephen P, Tomassian, Tamar, Zhang, Min   +5 more
core  

Super-resolution imaging of T lymphocyte activation reveals chromatin decondensation and disrupted nuclear envelope

Communications Biology
T lymphocyte activation plays a pivotal role in adaptive immune response and alters the spatial organization of nuclear architecture that subsequently impacts transcription activities.
Jianquan Xu, Xuejiao Sun, Zhangguo Chen, Hongqiang Ma, Yang Liu   +4 more
doaj   +1 more source

lymphocyte activation

Citation: 'lymphocyte activation' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13401 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire   +1 more source

Age-related changes of apoptotic cell death in human lymphocytes [PDF]

, 2006
Apoptosis seems to be involved in immunosenescence associated with aging. Moreover, in lymphocytes (PBL) of patients with Alzheimer's disease, an increased susceptibility to the apoptotic pathway has been described possibly due to impaired protection of ...
Eckert, Anne, Leutner, Silke, Müller, Walter E., Schindowski, Katharina   +3 more
core  

Attenuating Lymphocyte Activity [PDF]

Journal of Biological Chemistry, 2005
Deanne M. Compaan, Lino C. Gonzalez, Irene Tom, Kelly M. Loyet, Dan Eaton, Sarah G. Hymowitz   +5 more
openaire   +1 more source

Hypertension and immune activation in antiretroviral therapy naïve people living with human immunodeficiency virus

BMC Infectious Diseases
Background The pathogenesis of hypertension (HTN) in people living with HIV/AIDS (PLHIV) is complex and remains not fully understood. Chronic immune activation (IA) is postulated to be one of the culprits.
Tosi M. Mwakyandile, Grace A. Shayo, Philip G. Sasi, Ferdinand M. Mugusi, Godfrey Barabona, Takamasa Ueno, Eligius F. Lyamuya   +6 more
doaj   +1 more source

Prior Cytomegalovirus Infection Shapes Lymphocyte Activation and Function During Pregnancy. [PDF]

Int J Mol Sci
Ângelo-Dias M, Martins CG, Mata MA, Barata M, Chung A, Sarzedas S, Fernandes É, Marques A, Chasqueira MJ, Paixão P, Lima J, Borrego LM.   +11 more
europepmc   +1 more source

Author Correction: Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice

Nature Communications
Claire Soudais, Romane Schaus, Camille Bachelet, Norbert Minet, Sara Mouasni, Cécile Garcin, Caique Lopes Souza, Pierre David, Clara Cousu, Hélène Asnagli, Andrew Parker, Paul Palmquist-Gomes, Fernando E. Sepulveda, Sébastien Storck, Sigolène M. Meilhac, Alain Fischer, Emmanuel Martin, Sylvain Latour   +17 more
doaj   +1 more source