Results 81 to 90 of about 1,928,223 (200)

TUMOR-SPECIFIC IMMUNE RESPONSE AFTER PHOTODYNAMIC THERAPY

Медицинская иммунология, 2016
Increased incidence of malignancies requires a search for new therapeutic approaches. E.g., photodynamic therapy (PDT) is an effective anti-cancer treatment that involves administration of a photosensitizing dye followed by visible light irradiation of ...
Yu. N. Anokhin, E. V. Abakushina
doaj   +1 more source

Comparison of expression of molecular markers of peripheral blood lymphocyte activation in patients with small uveal melanoma and healthy controls

Journal of Ophthalmology, 2016
Background: Organ-saving treatment is indicated for patients with small (i.e., ? 3 mm in prominence) uveal melanomas (UM), that being the initial stage of the disease.
S.I. Poliakova, L.N. Velichko, A.V. Bogdanova, I.V. Tsukanova   +3 more
doaj   +1 more source

P1248: CTP SYNTHASE 1 IS A NOVEL TARGET IN T CELL CANCERS, WITH SMALL MOLECULE INHIBITION INDUCING DEATH OF NEOPLASTIC HUMAN T CELLS IN VITRO AND INHIBITION OF THEIR GROWTH IN AN IN VIVO XENOTRANSPLANT MODEL

HemaSphere, 2022
P. Beer, H. Asnagli, N. Minet, E. Hoeben, A. Parker, A. Fischer, S. Latour   +6 more
doaj   +1 more source

The Immune Response to Helicobacter pylori

Food Technology and Biotechnology, 2014
The immune response to Helicobacter pylori involves different mechanisms that are both protective and damaging to the host. The innate and the adaptive immune responses lead to inflammatory as well as anti-inflammatory responses, allowing for persistence
Marija Gubina, Alojz Ihan
doaj  

Role of caveolin-3 in lymphocyte activation [PDF]

, 2015
AIMS: Caveolins are structural proteins clustered in lipid-rich regions of plasma membrane involved in coordinating signal transduction in various organ systems.
Roth, David M, Stary, Creed M, Tran, Chinh, Schilling, Jan M, Bentley, Brandon, Patel, Hemal H   +5 more
core   +1 more source

Effects of Euphorbia milii latex on mitogen-induced lymphocyte proliferation

Revista Brasileira de Plantas Medicinais, 2014
The crude latex of "Crown-of-Thorns" (Euphorbia milii var hislopii, syn E.splendens) is a potent plant molluscicide. For this reason, toxicological studies have been performed to evaluate the health risks posed by its use in schistosomiasis control ...
I.F. Delgado, F.J.R. Paumgartten
doaj  

The OT-II model reveals dual in vitro and in vivo immunomodulatory properties of CD6 in T cell activation

Frontiers in Immunology
IntroductionCD6 is a signal transducing transmembrane glycoprotein expressed on T-cells and a subset of B and NK cells that has emerged as a promising therapeutic target in autoimmunity and cancer.The extracellular domain of CD6 interacts with endogenous
Alejandra Leyton-Pereira, Irene Fernández-Delgado, María José Rodríguez-Lagunas, Cristina Català, Sergi Casadó-Llombart, Noa Beatriz Martin-Cofreces, Noa Beatriz Martin-Cofreces, Noa Beatriz Martin-Cofreces, Eugenio Bustos-Morán, Natalia Díaz-Garrido, Marta Consuegra-Fernández, Ana Cristina Calpena, Ana Cristina Calpena, Fernando Aranda, María Velasco-de Andrés, Laura Baldomà, Francisco Sánchez-Madrid, Francisco Sánchez-Madrid, Francisco Lozano, Francisco Lozano, Francisco Lozano   +20 more
doaj   +1 more source

Blockade of αvβ6 and αvβ8 integrins with a chromogranin A-derived peptide inhibits TGFβ activation in tumors and suppresses tumor growth

Journal of Experimental & Clinical Cancer Research
Background The αvβ6- and αvβ8-integrins, two cell-adhesion receptors upregulated in many solid tumors, can promote the activation of transforming growth factor-β (TGFβ), a potent immunosuppressive cytokine, by interacting with the RGD sequence of the ...
Anna Maria Gasparri, Arianna Pocaterra, Barbara Colombo, Giulia Taiè, Chiara Gnasso, Alessandro Gori, Federica Pozzi, Andrew Smith, Fulvio Magni, Alessia Ugolini, Matteo Doglio, Maria Chiara Bonini, Anna Mondino, Angelo Corti, Flavio Curnis   +14 more
doaj   +1 more source

Phosphoinositide 3-kinases in T lymphocyte activation

, 2001
Biochemical experiments have established that the metabolism of inositol phospholipids by phosphoinositide 3-kinases (PI3Ks) and lipid-phosphatases is triggered by many receptors that control T lymphocyte function, including antigen-receptors ...
Ward, Stephen G., Doreen A Cantrell, Cantrell, Doreen A., Stephen G Ward   +3 more
core   +1 more source

Effect of neuropeptides and monoamines on lymphocyte activation

, 1988
Neuropeptides and monoamines have been found in tissues where immune reactions are initiated such as the skin, gut, and respiratory tract, and in these tissues neuropeptides and monoamines might be involved in the regulation of lymphocyte activation ...
Klas Nordlind, Sundström, E,, Viktor Mutt, Mutt, V, Erik Sundström, Nordlind, K   +5 more
core   +1 more source