Results 81 to 90 of about 506,913 (207)

Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. [PDF]

, 2015
OBJECTIVE: Unlike other herpes viruses, Kaposi's sarcoma-associated herpes virus (KSHV) is not ubiquitous worldwide and is most prevalent in sub-Saharan Africa. The reasons for this are unclear. As part of a wider investigation of factors that facilitate
Cose, Stephen, Drakeley, Christopher, Elliott, Alison, Miley, Wendell, Nalwoga, Angela, Ndibazza, Juliet, Newton, Robert, Wakeham, Katie, Whitby, Denise   +8 more
core   +2 more sources

The OT-II model reveals dual in vitro and in vivo immunomodulatory properties of CD6 in T cell activation

Frontiers in Immunology
IntroductionCD6 is a signal transducing transmembrane glycoprotein expressed on T-cells and a subset of B and NK cells that has emerged as a promising therapeutic target in autoimmunity and cancer.The extracellular domain of CD6 interacts with endogenous
Alejandra Leyton-Pereira, Irene Fernández-Delgado, María José Rodríguez-Lagunas, Cristina Català, Sergi Casadó-Llombart, Noa Beatriz Martin-Cofreces, Noa Beatriz Martin-Cofreces, Noa Beatriz Martin-Cofreces, Eugenio Bustos-Morán, Natalia Díaz-Garrido, Marta Consuegra-Fernández, Ana Cristina Calpena, Ana Cristina Calpena, Fernando Aranda, María Velasco-de Andrés, Laura Baldomà, Francisco Sánchez-Madrid, Francisco Sánchez-Madrid, Francisco Lozano, Francisco Lozano, Francisco Lozano   +20 more
doaj   +1 more source

A model for the differentiation of human natural killer cells. Studies on the in vitro activation of Leu-11+ granular lymphocytes with a natural killer-sensitive tumor cell, K562. [PDF]

, 1985
A subpopulation of low density granular lymphocytes that express the natural killer (NK) cell-associated Leu-11 antigen (IgG Fc receptor) were stimulated directly by coculture with an NK-sensitive tumor cell, K562.
Lanier, LL, Phillips, JH
core  

The Immune Response to Helicobacter pylori

Food Technology and Biotechnology, 2014
The immune response to Helicobacter pylori involves different mechanisms that are both protective and damaging to the host. The innate and the adaptive immune responses lead to inflammatory as well as anti-inflammatory responses, allowing for persistence
Marija Gubina, Alojz Ihan
doaj  

Blockade of αvβ6 and αvβ8 integrins with a chromogranin A-derived peptide inhibits TGFβ activation in tumors and suppresses tumor growth

Journal of Experimental & Clinical Cancer Research
Background The αvβ6- and αvβ8-integrins, two cell-adhesion receptors upregulated in many solid tumors, can promote the activation of transforming growth factor-β (TGFβ), a potent immunosuppressive cytokine, by interacting with the RGD sequence of the ...
Anna Maria Gasparri, Arianna Pocaterra, Barbara Colombo, Giulia Taiè, Chiara Gnasso, Alessandro Gori, Federica Pozzi, Andrew Smith, Fulvio Magni, Alessia Ugolini, Matteo Doglio, Maria Chiara Bonini, Anna Mondino, Angelo Corti, Flavio Curnis   +14 more
doaj   +1 more source

Immunomodulator Activity Of An Isolate From Artocarpus Champeden Spreng. On Cytotoxicity Function Of Cd8+ Of Mice [PDF]

, 2011
Research of traditional medicine is important to maximize the utilization of natural resources. Artocarpus champeden Spreng. is one of medicinal plants that must be studied because a lot of diseases have been treated traditionally with this plant, such ...
Kartini, Kartini
core  

Lymphocyte activation [PDF]

Journal of Cellular Biochemistry, 1994
openaire   +2 more sources

Effects of Euphorbia milii latex on mitogen-induced lymphocyte proliferation

Revista Brasileira de Plantas Medicinais, 2014
The crude latex of "Crown-of-Thorns" (Euphorbia milii var hislopii, syn E.splendens) is a potent plant molluscicide. For this reason, toxicological studies have been performed to evaluate the health risks posed by its use in schistosomiasis control ...
I.F. Delgado, F.J.R. Paumgartten
doaj  

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes

Redox Biology, 2019
While the role of mitochondrial metabolism in controlling T-lymphocyte activation and function is becoming more clear, the specifics of how mitochondrial redox signaling contributes to T-lymphocyte regulation remains elusive. Here, we examined the global
C.M. Moshfegh, C.W. Collins, V. Gunda, A. Vasanthakumar, J.Z. Cao, P.K. Singh, L.A. Godley, Adam J. Case   +7 more
doaj   +1 more source

Concepts of GPCR-controlled navigation in the immune system

, 2019
G-protein-coupled receptor (GPCR) signaling is essential for the spatiotemporal control of leukocyte dynamics during immune responses. For efficient navigation through mammalian tissues, most leukocyte types express more than one GPCR on their surface ...
Boneschansker L, Brandt SL, Chan EC, Filippo K, Freedman NJ, Hjorto GM, Hons M, Katakai T, Kitayama J, Lemos C, Ley K, Miyabe Y, Moussavi‐Harami SF, Proudfoot AEI, Purvanov V, Rot A, Scheiermann C, Schwarz J, Sokol CL, Sotsios Y, Steury MD, Takeda A, Thiriot A, Tomhave ED, Wang Y, Yanagihara S, Zhang Y   +26 more
core   +1 more source