Results 121 to 130 of about 338,332 (265)

Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis. [PDF]

Arthritis Res Ther, 2023
Pedersen JM, Hansen AS, Skejø C, Juul-Madsen K, Junker P, Hørslev-Petersen K, Hetland ML, Stengaard-Pedersen K, Østergaard M, Møller BK, Dreyer L, Hauge EM, Hvid M, Greisen S, Deleuran B.   +14 more
europepmc   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Fianlimab, a human lymphocyte activation gene-3 monoclonal antibody, in combination with cemiplimab: Tumor-specific expansion cohorts in advanced malignancies. [PDF]

Cancer
Kim TM, Williamson SK, Papadopoulos KP, Hamid O, Dy GK, McDermott R, Birnbaum A, Kaczmar JM, Lakhani N, Rischin D, Sarker D, Dowlati A, Zhu XH, Malhotra J, Pouliot JF, Mani J, Brennan L, Fang F, Chen S, Salvati M, Lowy I, Khaled A, Lewis KD, Kroog G, Fury MG, Cho BC.   +25 more
europepmc   +1 more source

Exploring the putative role of PRDM1 and PRDM2 transcripts as mediators of T lymphocyte activation. [PDF]

J Transl Med, 2023
Di Zazzo E, Rienzo M, Casamassimi A, De Rosa C, Medici N, Gazzerro P, Bifulco M, Abbondanza C.   +7 more
europepmc   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

P2RY13+ dendritic cells correlate with enhanced antigen presentation and lymphocyte activation in lung adenocarcinoma. [PDF]

Front Med (Lausanne)
Lan C, Zhong J, Che S.
europepmc   +1 more source

Water channel aquaporin 4 is required for T cell receptor mediated lymphocyte activation. [PDF]

J Leukoc Biol, 2023
Nicosia M, Lee J, Beavers A, Kish D, Farr GW, McGuirk PR, Pelletier MF, Lathia JD, Fairchild RL, Valujskikh A.   +9 more
europepmc   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

Expression and prognostic importance of lymphocyte activation gene 3 and CD73 in advanced or metastatic hepatocellular carcinoma. [PDF]

J Int Med Res
Ayhan M, Dogan A, Keser SH, Başak K, Akdeniz N, Atci MM, Erhan SS, Arikan R, Celikel C, Turan N, Yıldırım ME, Odabas H, Yıldırım S, Laçin Ş, Kostek O.   +14 more
europepmc   +1 more source

The Polyamine Putrescine Is a Positive Regulator of Group 3 Innate Lymphocyte Activation. [PDF]

Immunohorizons, 2023
Sah P, Zenewicz LA.
europepmc   +1 more source