Results 131 to 140 of about 359,313 (265)

Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis. [PDF]

Arthritis Res Ther, 2023
Pedersen JM, Hansen AS, Skejø C, Juul-Madsen K, Junker P, Hørslev-Petersen K, Hetland ML, Stengaard-Pedersen K, Østergaard M, Møller BK, Dreyer L, Hauge EM, Hvid M, Greisen S, Deleuran B.   +14 more
europepmc   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

Advanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias, Carmen Domínguez‐Alonso, Ivana Zagorac, Antonio Tapia‐Galisteo, Eva García‐Veros, Laura Rubio‐Pérez, Marina Gómez‐Rosel, Patricia Fuentes, Patricia Hernández‐López, Óscar Aguilar‐Sopeña, Laura Almagro‐Puente, Sonia Martínez‐González, Lucía Cañizares‐Moscato, María Rivas‐Sánchez, Belén Blanco, Ángel Ramírez‐Fernández, Laura Díez‐Alonso, Carmen Blanco‐Aparicio, Javier Arroyo‐Ródenas, Jorge Martínez‐Torrecuadrada, María L. Toribio, Pedro Roda‐Navarro, Anaïs Jiménez‐Reinoso, Luis Álvarez‐Vallina   +23 more
wiley   +1 more source

P2RY13+ dendritic cells correlate with enhanced antigen presentation and lymphocyte activation in lung adenocarcinoma. [PDF]

Front Med (Lausanne)
Lan C, Zhong J, Che S.
europepmc   +1 more source

Exploring the putative role of PRDM1 and PRDM2 transcripts as mediators of T lymphocyte activation. [PDF]

J Transl Med, 2023
Di Zazzo E, Rienzo M, Casamassimi A, De Rosa C, Medici N, Gazzerro P, Bifulco M, Abbondanza C.   +7 more
europepmc   +1 more source

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

Advanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li, Anguo Zhao, Qi Zhuang, Lei Peng, Rui Liang, Jiadong Zhao, Yang Liu, Dashi Deng, Peng Yu, Xiqi Peng, Shaohua Zhang, Song Wu   +11 more
wiley   +1 more source

Expression and prognostic importance of lymphocyte activation gene 3 and CD73 in advanced or metastatic hepatocellular carcinoma. [PDF]

J Int Med Res
Ayhan M, Dogan A, Keser SH, Başak K, Akdeniz N, Atci MM, Erhan SS, Arikan R, Celikel C, Turan N, Yıldırım ME, Odabas H, Yıldırım S, Laçin Ş, Kostek O.   +14 more
europepmc   +1 more source

Water channel aquaporin 4 is required for T cell receptor mediated lymphocyte activation. [PDF]

J Leukoc Biol, 2023
Nicosia M, Lee J, Beavers A, Kish D, Farr GW, McGuirk PR, Pelletier MF, Lathia JD, Fairchild RL, Valujskikh A.   +9 more
europepmc   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Pan cohort immune biomarker of CD8 lymphocyte activation enabling HGSOC outcome prediction and treatment response. [PDF]

Discov Oncol
Liu X, Zhang Z, Wang B, Qin L, Fan N, Wang R, Yu X, Han Q, Lu Z, Kikete S, Shi F, Chu C, Zhang Y, Niu L, Wei R, Wu J, Li X.   +16 more
europepmc   +1 more source

The Polyamine Putrescine Is a Positive Regulator of Group 3 Innate Lymphocyte Activation. [PDF]

Immunohorizons, 2023
Sah P, Zenewicz LA.
europepmc   +1 more source