Advanced Healthcare Materials, EarlyView.HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu +21 more
wiley +1 more source
Exploring the putative role of PRDM1 and PRDM2 transcripts as mediators of T lymphocyte activation. [PDF]
J Transl Med, 2023 Di Zazzo E +7 more
europepmc +1 more source
In Situ Activation of Pituitary-Infiltrating T Lymphocytes in Autoimmune Hypophysitis [PDF]
, 2017 Han-Huei Lin +9 more
openalex +1 more source
Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants
Advanced Healthcare Materials, EarlyView.We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay +3 more
wiley +1 more source
Water channel aquaporin 4 is required for T cell receptor mediated lymphocyte activation. [PDF]
J Leukoc Biol, 2023 Nicosia M +9 more
europepmc +1 more source
A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis
Advanced Healthcare Materials, EarlyView.The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra +8 more
wiley +1 more source
The Polyamine Putrescine Is a Positive Regulator of Group 3 Innate Lymphocyte Activation. [PDF]
Immunohorizons, 2023 Sah P, Zenewicz LA.
europepmc +1 more source
Sputum T lymphocytes in asthma, COPD and healthy subjects have the phenotype of activated intraepithelial T cells (CD69+ CD103+) [PDF]
, 2003 Maggie J. Leckie
openalex +1 more source
Advanced Healthcare Materials, EarlyView.The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba +18 more
wiley +1 more source
Prognostic significance of Lymphocyte-activation gene 3 (LAG3) in patients with solid tumors: a systematic review, meta-analysis and pan-cancer analysis. [PDF]
Cancer Cell Int, 2023 Li R +7 more
europepmc +1 more source