Results 241 to 250 of about 399,802 (272)
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1987
The T lymphocyte receptor for antigen and histocompatibility molecules is a molecular complex comprised of five polypeptide chains. Both the 49KD alpha and 43KD beta chains are immunoglobulin-like and thus contain variable domains responsible for ligand binding.
Hsiu-Ching Chang +5 more
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The T lymphocyte receptor for antigen and histocompatibility molecules is a molecular complex comprised of five polypeptide chains. Both the 49KD alpha and 43KD beta chains are immunoglobulin-like and thus contain variable domains responsible for ligand binding.
Hsiu-Ching Chang +5 more
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T Lymphocyte Activation in Patients with Active Tuberculosis
American Review of Respiratory Disease, 1991Soluble interleukin-2 receptor (sIL-2R) is a marker of T lymphocyte activation. We measured the amount of serum sIL-2R in 35 patients with active tuberculosis before the initiation of antituberculous treatment. Twenty had pulmonary parenchymal lesion, 8 had tuberculous pleural effusion, and 7 had tuberculous lymphadenitis.
Leung, JCK, Lai, KN, Lai, CKW, Chan, CHS
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Effects of cadmium on lymphocyte activation
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989The effects of cadmium (Cd) on phytohemoagglutinin or phorbol myristate acetate-induced lymphocyte activation were investigated and a dose-dependent inhibition of cell proliferation was found. Kinetic studies revealed that the Cd-sensitive step is an early event of T cell stimulation. Failure of IL2 secretion and reduction of IL2 receptor expression in
Grazia Cifone M +7 more
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Lymphocyte Subsets and Activation in Prediabetes
Diabetes, 1986Peripheral blood lymphocytes were obtained from 65 individuals: 34 nondiabetic patients with islet cell autoantibodies (ICA) (prediabetic phase), 9 patients with newly diagnosed insulin-dependent diabetes mellitus (IDDM), 6 ICA-negative siblings or offsprings of IDDM patients, and 16 ICA-negative controls.
R Pyka +4 more
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Lipid rafts in lymphocyte activation
Microbes and Infection, 2004The existence of sphingolipid- and cholesterol-rich membrane microdomains called "lipid rafts", as well as their role in lymphocyte biology, has been widely debated during the last few years. Plasma membrane microdomains seem to be primarily involved in initiation and propagation of the signal transduction cascade associated with lymphocyte activation.
PIZZO, PAOLA, VIOLA A.
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Immunology Today, 1981
A review focussing on the lessons learned from polyclonal activation of B cells.
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A review focussing on the lessons learned from polyclonal activation of B cells.
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Cytotoxic activity of lymphocytes
Cellular Immunology, 1979Abstract Cell-free extracts of human lymphocytes activated by PHA contain a cytotoxin that kills mouse L cells. Such cells elaborate two different kinds of toxins into the culture supernatant fluids, called α- and β-lymphotoxin (-LT), which differ in size, stability, and antigenicity.
Sheng-Chung Lee, Zoltan J. Lucas
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Activation signals of T lymphocytes in microgravity
Journal of Biotechnology, 1996Human peripheral blood lymphocytes and monocytes were activated with concanavalin A with or without exogenous recombinant interleukin 1 (IL-1) alone or IL-1 + interleukin 2 (IL-2) under microgravity conditions to test the hypothesis that lack of production of IL-1 by monocytes is the cause of the near total loss of activation observed earlier on ...
PIPPIA P +5 more
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Mechanisms of T lymphocyte activation
Immunology Letters, 1991The proliferation of T lymphocytes in response to an antigenic stimulus requires the successive ligation of a range of T lymphocyte receptors by MHC-presented antigen, molecules expressed on the surfaces of accessory cells and lymphokines. A range of intracellular signalling systems are involved, with the possibility of alternative activation pathways ...
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Calcium and T lymphocyte activation
Cell, 1989A prolonged (at least 2-4 hr) elevation of [Ca2+]i accompanies early T cell activation by TCR/CD3-specific ligands. Ca2+ is generally thought to be an essential second messenger for early activation, but the precise molecular events contingent upon the Ca2+ signal remain to be determined.
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