Results 41 to 50 of about 2,075,479 (379)

A Method for Counting Phytohemagglutinin-Stimulated Lymphocytes [PDF]

Blood, 1967
Abstract A technic is described for accurately enumerating the number of viable. PHA-stimulated lymphocytes in culture. This technic is both simple and fast. The technic depends upon the elimination of debris by means of the proteolytic enzyme, pronase, and the removal of cell cytoplasm by cetrimide leaving clean, intact ...
M. Ingram, C. C. Stewart
openaire   +2 more sources

Decreased Absolute Lymphocyte Count and Increased Neutrophil/Lymphocyte Ratio With Immune Checkpoint Inhibitor–Associated Myocarditis

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background Myocarditis attributable to immune checkpoint inhibitor (ICI) therapy is a potentially fatal immune‐related adverse event. Limited data have suggested an association between baseline and on‐treatment absolute lymphocyte count (ALC) and ...
Z. Drobni, A. Zafar, L. Zubiri, Daniel A. Zlotoff, R. Alvi, Charlotte E. Lee, Sarah B Hartmann, H. Gilman, A. Villani, A. Nohria, J. Groarke, R. Sullivan, K. Reynolds, Lili Zhang, T. Neilan   +14 more
semanticscholar   +1 more source

Performance Evaluation of High Fluorescence Lymphocyte Count: Comparability to Atypical Lymphocyte Count and Clinical Significance [PDF]

Laboratory Medicine, 2018
To investigate the association between high-fluorescence lymphocyte cell (HFLC) and atypical lymphocyte (AL) counts, and to determine the clinical significance of HFLC.We compared automated HFLC and microscopic AL counts and analyzed the findings. Patient clinical data for each specimen were reviewed.A total of 320 blood specimens were included.
Chaicharoen Tantanate, Cherdsak Klinbua
openaire   +3 more sources

Absolute lymphocyte count is a prognostic marker in Covid‐19: A retrospective cohort review

International Journal of Laboratory Hematology, 2020
Prognostic factors are needed to aid clinicians in managing Covid‐19, a respiratory illness. Lymphocytopenia has emerged as a simply obtained laboratory value that may correlate with prognosis.
J. Wagner, A. Dupont, Scott A. Larson, B. Cash, A. Farooq   +4 more
semanticscholar   +1 more source

A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study [PDF]

, 2006
Objective: The objective of the trial was to evaluate in a pilot setting the safety and efficacy of interleukin-2 (IL-2) therapy when used without concomitant antiretroviral therapy as a treatment for HIV infection.
Abrams, Ann Sullivan, Carr, Carr, Carr, Christian Herzmann, Clive Loveday, Connelly, Crespo-Fierro, Davey, Davey, Davey, Dewar, Emery, Emery, Emery, George Janossy, H. Clifford Lane, Handan Wand, Jorge A Tavel, Kovacs, Kovacs, Lederman, Levy, Lisa Fosdick, Losso, Margaret A Johnson, Mark Nelson, Martin Fisher, Matthews, Mercolino, Mike Youle, Palella, Pillay, Pozniak, Richard T Davey, Ruxrungtham, Sean Emery, Sereti, Sereti, Smith, Stein, Urdea, Verbeke, Yeni   +44 more
core   +2 more sources

hIL‐7‐hyFc, A Long‐Acting IL‐7, Increased Absolute Lymphocyte Count in Healthy Subjects

Clinical and Translational Science, 2020
A low lymphocyte count puts immune‐compromised patients at risk of mortality. hIL‐7‐hyFc is a homodimeric interleukin‐7 (IL‐7), a potent T‐cell amplifier, fused to the hybridizing IgD/IgG4 immunoglobulin domain.
Sang Won Lee, Donghoon Choi, Minkyu Heo, E. Shin, Su‐Hyung Park, So Jeong Kim, Yeon-Kyung Oh, Byung Ha Lee, Se‐Hwan Yang, Y. Sung, Howard Lee   +10 more
semanticscholar   +1 more source

Is higher lymphocyte count a potential strategy for preventing chronic kidney disease in patients receiving long-term dasatinib treatment?

Journal of Pharmaceutical Health Care and Sciences, 2023
Background Dasatinib, which is used to treat treating chronic myeloid leukemia, induces increases in blood lymphocytes during the treatment. In addition, neutrophil–lymphocyte count ratio (NLR) is associated with the related to development of chronic ...
Hirokazu Nakayama, Hiromitsu Iizuka, Toshiaki Kato, Kensuke Usuki   +3 more
doaj   +1 more source

Mature and Immature/Activated Cells Fractionation: Time for a Paradigm Shift in Differential Leucocyte Count Reporting?

Diagnostics, 2021
Leucocytes, especially neutrophils featuring pro- and anti-cancerous characteristics, are involved in nearly every stage of tumorigenesis. Phenotypic and functional differences among mature and immature neutrophil fractions are well reported, and their ...
Rana Zeeshan Haider, Najeed Ahmed Khan, Eloisa Urrechaga, Tahir Sultan Shamsi   +3 more
doaj   +1 more source

Real World Lab Data: Patterns of Lymphocyte Counts in Fingolimod Treated Patients

Frontiers in Immunology, 2018
Objective:Fingolimod is approved for the treatment of highly active relapsing remitting multiple sclerosis (MS) patients and acts by its unique mechanism of action via sphingosine-1-phosphate receptor-modulation.
Maxi Kaufmann, Rocco Haase, Undine Proschmann, Tjalf Ziemssen, Katja Akgün   +4 more
doaj   +1 more source

Impact of lymphocyte differential count > 15% in BALF on the mortality of patients with acute exacerbation of chronic fibrosing idiopathic interstitial pneumonia

BMC Pulmonary Medicine, 2017
Background Chronic fibrosing idiopathic interstitial pneumonia (CFIIP) has a potential risk of acute exacerbation (AE). However, the usefulness of cellular analysis of bronchoalveolar lavage fluid (BALF) has never been evaluated.
Reoto Takei, Machiko Arita, Shogo Kumagai, Yuhei Ito, Maki Noyama, Fumiaki Tokioka, Tadashi Ishida   +6 more
doaj   +1 more source