Results 1 to 10 of about 168,260 (202)

Expression of PD-1 on CD4+ Tumor-Infiltrating Lymphocytes in Tumor Microenvironment Associated with Pathological Characteristics of Breast Cancer

Journal of Immunology Research, 2018
Objective. This study aimed to investigate the correlation of CD4+/PD-1+ or CD4+/PD-1− tumor-infiltrating lymphocytes with pathological characteristics in breast cancer patients. Methods.
Yan-Jie Zhao, Jian Zhang, Feng Shi, Zhi-Ping Hu, Jiang-Ping Wu, Guang-Jiang Wu, Rui-Bin Wang, Quan Zhou, Hong Chang, Ying-Nan Li, Qing-Kun Song   +10 more
doaj   +1 more source

PD-L1 expression on stromal tumor-infiltrating lymphocytes is a favorable prognostic factor in ovarian serous carcinoma

Journal of Ovarian Research, 2019
Background PD-L1 expression levels determined by immunostaining are known to be related to the survival rate and prognosis of patients with various types of cancers, as well as to the therapeutic response to immune checkpoint inhibitors.
Ki Hyung Kim, Kyung Un Choi, Ahrong Kim, So Jung Lee, Jung Hee Lee, Dong Soo Suh, Byung-su Kwon, Chungsu Hwang   +7 more
doaj   +1 more source

Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma [PDF]

Anais Brasileiros de Dermatologia, 2019
: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered in the decision to perform this ...
Fernando De Marco dos Santos, Felipe Correa da Silva, Julia Pedron, Roque Domingos Furian, Cristina Fortes, Renan Rangel Bonamigo   +5 more
doaj   +1 more source

Tumor-infiltrating lymphocytes and breast cancer: Beyond the prognostic and predictive utility

Tumor Biology, 2017
The importance of the immune system as a potent anti-tumor defense has been consolidated in recent times, and novel immune-related therapies are today demonstrating a strong clinical benefit in the setting of several solid neoplasms.
Andrea Ravelli, Giandomenico Roviello, Daniele Cretella, Andrea Cavazzoni, Alessandra Biondi, Maria Rosa Cappelletti, Laura Zanotti, Giuseppina Ferrero, Marco Ungari, Fabrizio Zanconati, Alberto Bottini, Roberta Alfieri, Pier Giorgio Petronini, Daniele Generali   +13 more
doaj   +1 more source

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer [PDF]

, 2012
A summit on cellular therapy for cancer discussed and presented advances related to the use of adoptive cellular therapy for melanoma and other cancers. The summit revealed that this field is advancing rapidly.
A Lundqvist, A Somers, C Berger, CA Tran, Carolina Berger, Cornelis JM Melief, Daniel J Powell, David F Stroncek, DG Song, DJ Powell Jr, DL Porter, Francesco M Marincola, G Mostoslavsky, GG Kenter, Gustavo Mostoslavsky, J Jin, J Staerk, James R Heath, Jeffrey S Miller, JN Kochenderfer, JN Kochenderfer, John O'Shea, JS Miller, K Takahashi, L Gattinoni, L Gattinoni, L Gattinoni, L Gattinoni, LA Johnson, Luca Gattinoni, M Kalos, M Kalos, M Kalos, Mahendra Rao, Mark E Dudley, Martin A Cheever, ME Dudley, ME Dudley, Michael Kalos, Nicholas P Restifo, P Muranski, Peter Flynn, PF Robbins, RA Morgan, Richard W Childs, SA Rosenberg, Steven A Rosenberg, TS Park, X Wang   +48 more
core   +4 more sources

Human plasmacytoid dendritic cells and cutaneous melanoma [PDF]

, 2020
The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Bugatti, Mattia, Consoli, Francesca, Monti, Matilde, Vermi, William, Vescovi, Raffaella   +4 more
core   +2 more sources

ASSESSMENT OF STROMAL AND INTRA-EPITHELIAL TUMOR INFILTRATING LYMPHOCYTES IN COLORECTAL CARCINOMA AT ARMED FORCES INSTITUTE OF PATHOLOGY

Pakistan Armed Forces Medical Journal, 2021
Objective: To conduct a morphological evaluation quantitatively of two types of tumor-infiltrating lymphocyte populations, including those located in the stroma and intraepithelial cancer structures, in patients with colorectal cancer.
Amna Ameer, Farhan Akhtar, Hafeez Ud Din, Rabia Ahmed   +3 more
doaj   +1 more source

Clinicopathological significance and prognostic role of tumor-infiltrating lymphocytes in colorectal cancer

The International Journal of Biological Markers, 2019
Purpose: This study aimed to elucidate the clinicopathological significance and prognostic role of tumor-infiltrating lymphocytes in colorectal cancer. Methods: The immunohistochemistry of CD3 and CD8 was performed on 265 human colorectal cancer tissues ...
Young San Ko, Jung-Soo Pyo
doaj   +1 more source

Higher Numbers of T-Bet+ Tumor-Infiltrating Lymphocytes Associate with Better Survival in Human Epithelial Ovarian Cancer

Cellular Physiology and Biochemistry, 2017
Background/Aims: T-bet, a member of the T-box family of transcription factors, is a key marker of type I immune response within the tumor microenvironment, and has been previously reported by us to serve as an important prognostic indicator for human ...
Yun Xu, Lujun Chen, Bin Xu, Yuqi Xiong, Min Yang, Xiaohui Rui, Liangrong Shi, Changping Wu, Jingting Jiang, Binfeng Lu   +9 more
doaj   +1 more source

Marsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer

Frontiers in Immunology, 2023
IntroductionTumor-infiltrating T lymphocytes in the tumor microenvironment are critical factors influencing the prognosis and chemotherapy outcomes. As a Chinese herbal medicine, Marsdenia tenacissima extract (MTE) has been widely used to treat cancer in
Ben Yi, Ben Yi, Shuai Zhang, Suying Yan, Suying Yan, Yanfei Liu, Yanfei Liu, Zhiqiang Feng, Zhiqiang Feng, Tianhao Chu, Tianhao Chu, Jun Liu, Wei Wang, Jun Xue, Chunze Zhang, Yijia Wang   +15 more
doaj   +1 more source