Results 131 to 140 of about 115,529 (261)

CD8+ T Lymphocytes in Pituitary Neuroendocrine Tumors: Friend or Foe? [PDF]

Cells
Nastase VN, Ceausu AR, Burcea IF, Dumitriu-Stan RI, Gaje PN, Zara F, Raica M, Albai O, Poiana C, Timar B.   +9 more
europepmc   +1 more source

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

Advanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang, Qiqi Qi, Dezhong Li, Jingshi Tang, Weifeng Wang, Zushun Xu, Qi Xu, Fangfang Du, Qianyuan He   +8 more
wiley   +1 more source

Activation of tumor-specific CD8+ T cells prior to radiopharmaceutical therapy improves antitumor response. [PDF]

J Immunother Cancer
Shim D, Mouton C, Moseman JE, Comas Rojas H, Jeon D, Idrissou MB, Hernandez R, Weichert JP, McNeel DG.   +8 more
europepmc   +1 more source

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

Role of tumor-infiltrating lymphocytes in melanoma

Turkish Journal of Plastic Surgery, 2019
Yasemin Benderli Cihan
doaj   +1 more source

Spontaneous Regression of Poorly Differentiated Carcinoma in the Transverse Colon with Deficient Mismatch Repair: A Case Report and Review. [PDF]

Surg Case Rep
Takeyama D, Mizuno F, Suzuki T, Nakamura A, Harata TJ, Chubachi S.   +5 more
europepmc   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Correction: An integrated automated deep learning framework for annotating tumor-infiltrating lymphocytes in lung adenocarcinoma pathology. [PDF]

Front Bioinform
Li X, Wei KL, Huang ZQ, Huang ZY.
europepmc   +1 more source

CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors

Advanced Science, EarlyView.
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen, Xiaoyun Luo, Huixin Gao, Yujing Ke, Yu Zhan, Xiaoting Xu, Xiaoxiao Xiong, Fengjiao Wei, Si Yang, Zhonghua Liu, Bolan Yu, Zhaofeng Huang, Yingjie Bian   +12 more
wiley   +1 more source

Hepatic Artery Embolization Reduces Tumor-infiltrating-CD8-positive Lymphocytes in an Orthotopic Rat Hepatocellular Carcinoma Model. [PDF]

Interv Radiol (Higashimatsuyama)
Takaki H, Wada R, Ueshima E, Kodama H, Hisai T, Yamakado K.   +5 more
europepmc   +1 more source