Results 31 to 40 of about 311,006 (351)

HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]

, 2018
Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula, Braga, Sofia, Cabral, M. Guadalupe, Jacinto, António, Saraiva, Diana P.   +4 more
core   +2 more sources

TUMOR-INFILTRATING LYMPHOCYTES IN TRIPLE NEGATIVE BREAST CANCER: CORRELATIVE ANALYSES OF OWN DATA AND LITERATURE REVIEW

Ukrainian Scientific Medical Youth Journal, 2019
The article summarizes data and presents own study about the value of tumor-infiltrating lymphocytes as a prognostic factor for breast cancer including triple negative breast cancer lacking estrogen and progesterone receptors and HER2\new amplification ...
Liubov Zakhartseva, Mariia Yanovytska
doaj   +1 more source

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014.

Annals of Oncology, 2015
BACKGROUND The morphological evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer (BC) is gaining momentum as evidence strengthens for the clinical relevance of this immunological biomarker.
R. Salgado, R. Salgado, C. Denkert, S. Demaria, N. Sirtaine, F. Klauschen, G. Pruneri, S. Wienert, G. V. D. Eynden, F. Baehner, F. Penault-Llorca, E. A. Perez, E. Thompson, W. Symmans, A. Richardson, J. Brock, C. Criscitiello, H. Bailey, M. Ignatiadis, G. Floris, J. Sparano, Z. Kos, T. Nielsen, D. Rimm, K. Allison, J. Reis-Filho, S. Loibl, C. Sotiriou, G. Viale, S. Badve, S. Adams, K. Willard-Gallo, S. Loi   +32 more
semanticscholar   +1 more source

Relevance of tumor-infiltrating lymphocytes in breast cancer [PDF]

BMC Medicine, 2015
While breast cancer has not been considered a cancer amenable to immunotherapeutic approaches, recent studies have demonstrated evidence of significant immune cell infiltration via tumor-infiltrating lymphocytes in a subset of patient tumors. In this review we present the current evidence highlighting the clinical relevance and utility of tumor ...
Phillip K. Darcy, Phillip K. Darcy, Mariam Mansour, Zhi Ling Teo, Chenhao Zhou, Paul A. Beavis, Peter Savas, Sathana Dushyanthen, Sherene Loi, Sherene Loi   +9 more
openaire   +4 more sources

Dynamics of the intratumoral immune response during progression of high-grade serous ovarian cancer [PDF]

, 2018
PURPOSE: Tumor-infiltrating lymphocytes (TILs) have an established impact on the prognosis of high-grade serous ovarian carcinoma (HGSOC), however, their role in recurrent ovarian cancer is largely unknown.
Braicu, I, Budczies, J, Castillo-Tong, DC, Darb-Esfahani, S, Denkert, C, Gabra, H, Ganapathi, RN, Gourley, C, Jöhrens, K, Kolaschinski, I, Kreuzinger, C, Kulbe, H, Lambrechts, S, Ruscito, I, Schmitt, W, Sehouli, J, Stanske, M, Vergote, I, Wienert, S   +18 more
core   +4 more sources

Expression of PD-1 on CD4+ Tumor-Infiltrating Lymphocytes in Tumor Microenvironment Associated with Pathological Characteristics of Breast Cancer

Journal of Immunology Research, 2018
Objective. This study aimed to investigate the correlation of CD4+/PD-1+ or CD4+/PD-1− tumor-infiltrating lymphocytes with pathological characteristics in breast cancer patients. Methods.
Yan-Jie Zhao, Jian Zhang, Feng Shi, Zhi-Ping Hu, Jiang-Ping Wu, Guang-Jiang Wu, Rui-Bin Wang, Quan Zhou, Hong Chang, Ying-Nan Li, Qing-Kun Song   +10 more
doaj   +1 more source

PD-L1 expression on stromal tumor-infiltrating lymphocytes is a favorable prognostic factor in ovarian serous carcinoma

Journal of Ovarian Research, 2019
Background PD-L1 expression levels determined by immunostaining are known to be related to the survival rate and prognosis of patients with various types of cancers, as well as to the therapeutic response to immune checkpoint inhibitors.
Ki Hyung Kim, Kyung Un Choi, Ahrong Kim, So Jung Lee, Jung Hee Lee, Dong Soo Suh, Byung-su Kwon, Chungsu Hwang   +7 more
doaj   +1 more source

Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma [PDF]

Anais Brasileiros de Dermatologia, 2019
: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered in the decision to perform this ...
Fernando De Marco dos Santos, Felipe Correa da Silva, Julia Pedron, Roque Domingos Furian, Cristina Fortes, Renan Rangel Bonamigo   +5 more
doaj   +1 more source

Marsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer

Frontiers in Immunology, 2023
IntroductionTumor-infiltrating T lymphocytes in the tumor microenvironment are critical factors influencing the prognosis and chemotherapy outcomes. As a Chinese herbal medicine, Marsdenia tenacissima extract (MTE) has been widely used to treat cancer in
Ben Yi, Ben Yi, Shuai Zhang, Suying Yan, Suying Yan, Yanfei Liu, Yanfei Liu, Zhiqiang Feng, Zhiqiang Feng, Tianhao Chu, Tianhao Chu, Jun Liu, Wei Wang, Jun Xue, Chunze Zhang, Yijia Wang   +15 more
doaj   +1 more source

The Prognostic Implications of Tumor Infiltrating Lymphocytes in Colorectal Cancer: A Systematic Review and Meta-Analysis

Scientific Reports, 2020
Tumor-infiltrating lymphocytes (TILs) are an important histopathologic feature of colorectal cancer that confer prognostic information. Previous clinical and epidemiologic studies have found that the presence and quantification of tumor-infiltrating ...
G. Idos, Janet Kwok, Nirupama Bonthala, Lynn Kysh, S. Gruber, C. Qu   +5 more
semanticscholar   +1 more source