Results 11 to 20 of about 1,277,196 (314)

Hematopoiesis: A Layered Organization Across Chordate Species

Frontiers in Cell and Developmental Biology, 2020
The identification of distinct waves of progenitors during development, each corresponding to a specific time, space, and function, provided the basis for the concept of a “layered” organization in development.
Ramy Elsaid, Ramy Elsaid, Ramy Elsaid, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Marcia Peixoto, Marcia Peixoto, Marcia Peixoto, Marcia Peixoto, Marcia Peixoto, Dali Amiri, Dali Amiri, Dali Amiri, Nathan Mackowski, Nathan Mackowski, Nathan Mackowski, Pablo Pereira, Pablo Pereira, Pablo Pereira, Antonio Bandeira, Antonio Bandeira, Antonio Bandeira, Ana Cumano, Ana Cumano, Ana Cumano   +28 more
doaj   +1 more source

STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly described ...
Marjolaine Debant, Miguel Burgos, Patrice Hemon, Paul Buscaglia, Tinhinane Fali, Sarra Melayah, Nelig Le Goux, Christophe Vandier, Marie Potier-Cartereau, Jacques-Olivier Pers, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Olivier Mignen, Yves Renaudineau   +14 more
doaj   +1 more source

Rheumatological features of Whipple disease

Scientific Reports, 2021
Whipple disease (WD) is a rare infectious systemic disease. Rheumatologists are at the frontline of WD diagnosis due to the early rheumatological manifestations. An early diagnosis is crucial, as usual anti-rheumatic drugs, especially TNF inhibitors, may
Alice Tison, Pauline Preuss, Clémentine Leleu, François Robin, Adrien Le Pluart, Justine Vix, Guillaume Le Mélédo, Philippe Goupille, Elisabeth Gervais, Grégoire Cormier, Jean-David Albert, Aleth Perdriger, Béatrice Bouvard, Jean-Marie Berthelot, Nathan Foulquier, Alain Saraux, the network of rheumatologists from the Grand Ouest “VICTOR HUGO”   +16 more
doaj   +1 more source

Discrimination of human cytotoxic lymphocytes from regulatory and B-lymphocytes by orthogonal light scattering [PDF]

, 1986
Light scattering properties of human lymphocyte subpopulations selected by immunofluorescence were studied with a flow cytometer. Regulatory and B-lymphocytes showed a low orthogonal light scatter signal, whereas cytotoxic lymphocytes identified with leu-
Berkel, W. van, Greve, J., Grooth, B.G. de, Napel, C.H.H. ten, Terstappen, L.W.M.M.   +4 more
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Pacific-Ciguatoxin-2 and Brevetoxin-1 Induce the Sensitization of Sensory Receptors Mediating Pain and Pruritus in Sensory Neurons

Marine Drugs, 2021
Ciguatera fish poisoning (CFP) and neurotoxic shellfish poisoning syndromes are induced by the consumption of seafood contaminated by ciguatoxins and brevetoxins.
Ophélie Pierre, Maxime Fouchard, Nelig Le Goux, Paul Buscaglia, Raphaël Leschiera, Richard J. Lewis, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +9 more
doaj   +1 more source

Simultaneous expression of CD4 and CD8 antigens by a substantial proportion of resting porcine T lymphocytes [PDF]

, 1987
The existence of four subpopulations in resting porcine T lymphocytes is documented. In addition to the two known subpopulations which are typified by a mutually exclusive expression of either the CD8 or the CD4 differentiation antigen, CD4-CD8+ and CD4 ...
Bevan, Bielefeldt Ohmann, Blue, Blue, Davignon, Fazekas de St. Groth, Goverman, Jonjić, Lanier, Lanier, MacDonald, Mackay, Pescovitz, Pescovitz, Reinherz, Reinherz, Saalmüller, Scollay, Swain, Tumbleson   +19 more
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CD20 and CD19 targeted vectors induce minimal activation of resting B lymphocytes [PDF]

, 2013
B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors ...
A Pezzutto, A Yoder, AD Bucheit, B Anliker, C Demaison, C Frecha, C Frecha, C Frecha, CA Walshe, Christian J. Buchholz, CJ Buchholz, D Unutmaz, DA Tuveson, DD Sloan, Els Verhoeyen, Evren Alici, François-Loic Cosset, H Li, H Niiro, J Bruenke, J Uchida, JT Golay, K Akashi, K Itoh, L Ginaldi, M Fujimoto, M Kügler, M Peipp, M Serafini, M Zanetti, MD Mühlebach, Michael Schwenkert, MJ Polyak, MS Cragg, NE Harwood, Q Zhou, Q Zhou, Q Zhou, Qi Zhou, R Zufferey, RC Münch, RN Damle, RS Noyce, S Funke, S Kheirallah, S Kneissl, Sabrina Kneissl, T Nakamura, TF Tedder, X Li, Y Reiter, YD Korin   +51 more
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Simulated patient and role play methodologies for communication skills and empathy training of undergraduate medical students

BMC Medical Education, 2020
Background Verbal and non-verbal communication, as well as empathy are central to patient-doctor interactions and have been associated with patients’ satisfaction. Non-verbal communication tends to override verbal messages.
Cristina Bagacean, Ianis Cousin, Anne-Helene Ubertini, Mohamed El Yacoubi El Idrissi, Anne Bordron, Lolita Mercadie, Leonor Canales Garcia, Jean-Christophe Ianotto, Philine De Vries, Christian Berthou   +9 more
doaj   +1 more source

Immunomagnetic t-lymphocyte depletion (ITLD) of rat bone marrow using OX-19 monoclonal antibody [PDF]

, 1989
Graft versus host disease (GVHD) may be abrogated and host survival prolonged by in vitro depletion of T lymphocytes from bone marrow (BM) prior to allotransplantation. Using a mouse anti-rat pan T-lymphocyte monoclonal antibody (0×19) bound to monosized,
A. Pascualone, A.L. Hoffman, B.F. Banner, Barclay A, Berenson R J, Beschorner W E, Bril H, D.G. Sheahan, D.V. Cramer, Dallman M J, Elkins W L, Farnsworth A, Filipovich A H, Kvalheim G, L. Makowka, Lubaroff D M, Martin P J, Monchik G J, Oaks M K, P. Rettinger, Prentice H G, Reisner Y, Rodt H, Slavin R E, T.E. Starzl, Thtschka P J, Tsoi M-S, Van Bekkum D W, Vartdal F, Waldman H, X. Cai   +30 more
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Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]

, 2019
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid, Couck, Liesbeth, Favoreel, Herman, Laval, Kathlyn, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +7 more
core   +1 more source