Results 11 to 20 of about 927,466 (317)

Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research

open access: yesFrontiers in Immunology, 2022
Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais   +5 more
doaj   +1 more source

The Notch signaling pathway involvement in innate lymphoid cell biology

open access: yesBiomedical Journal, 2021
The role of Notch in the immune system was first described in the late 90s. Reports revealed that Notch is one of the most conserved developmental pathways involved in diverse biological processes such as the development, differentiation, survival and ...
Rachel Golub
doaj   +1 more source

Deciphering the maturation of tertiary lymphoid structures in cancer and inflammatory diseases of the digestive tract using imaging mass cytometry

open access: yesFrontiers in Immunology, 2023
Persistent inflammation can promote the development of tertiary lymphoid structures (TLS) within tissues resembling secondary lymphoid organs (SLO) such as lymph nodes (LN).
Marion Le Rochais   +10 more
doaj   +1 more source

Lymphocytes [PDF]

open access: yesThe Oncologist, 1999
Abstract Mechanisms in Hematology is a book with an accompanying interactive CD-ROM designed to assemble basic concepts that underlie clinical understanding and progress. It is presented as a concise text with a series of diagrams that distill diffuse information into a compact form.
L G, Israels, E D, Israels
openaire   +2 more sources

Age-related accumulation of B-1 cell progenitors in mice reflects changes in miR15a/16-1 expression and radioresistance capacity

open access: yesExperimental Hematology & Oncology, 2023
Hyperproliferative diseases such as Chronic Lymphocytic Leukemia (CLL) and Systemic Lupus Erythematosus (SLE) are potentially related to some disturbance in the apoptosis pathway, specifically in B-1a cells (CD5+).
Olívia F Souza   +5 more
doaj   +1 more source

Could AMPs and B-cells be the missing link in understanding periodontitis?

open access: yesFrontiers in Immunology, 2022
Periodontal diseases are common inflammatory conditions characterized by bone loss in response to simultaneous bacterial aggression and host defenses. The etiology of such diseases is still not completely understood, however.
Vanessa Dominique Lobognon   +2 more
doaj   +1 more source

IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates

open access: yesFrontiers in Immunology, 2021
Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot   +9 more
doaj   +1 more source

Lymphocytic gastritis [PDF]

open access: yesPolish Journal of Pathology, 2019
Organic basis of gastrointestinal symptoms is in the scope of many specialists. In this article lymphocytic gastritis, relatively newly described and not widely-known entity is presented. The lesion is characterized by presence of numerous mature lymphocytes in the surface and foveolar epithelium, as well as lymphocytic infiltration of the lamina ...
Michał Puderecki   +3 more
openaire   +4 more sources

3. Lymphocytes [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2003
The fundamental task of the immune system is to defend "self" from "nonself." Lymphocytes are the primary cells of the immune system that developed one of the most sophisticated and comprehensive defense mechanisms in the biological system. T cells play a central role in orchestrating the immune response.
Rafeul, Alam, Magdalena, Gorska
openaire   +2 more sources

T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations

open access: yesFrontiers in Immunology, 2023
Familial adenomatous polyposis (FAP) is an inherited disease characterized by the development of large number of colorectal adenomas with high risk of evolving into colorectal tumors. Mutations of the Adenomatous polyposis coli (APC) gene is often at the
Céline Cuche   +27 more
doaj   +1 more source

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