Results 11 to 20 of about 1,988,114 (430)
Neutrophil-to-Lymphocyte, Platelet-to-Lymphocyte and Monocyte-to-Lymphocyte Ratio in Bipolar Disorder [PDF]
Background: Several inflammatory hypotheses have been suggested to explain the etiopathogenesis of bipolar disorder (BD) and its different phases. Neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), and monocyte-to-lymphocyte (MLR) ratios have been proposed as potential peripheral biomarkers of mood episodes.
Antimo Natale+9 more
openaire +6 more sources
Abstract Mechanisms in Hematology is a book with an accompanying interactive CD-ROM designed to assemble basic concepts that underlie clinical understanding and progress. It is presented as a concise text with a series of diagrams that distill diffuse information into a compact form.
Esther D. Israels, Lyonel G. Israels and
openaire +3 more sources
The role of preoperative levels of serum IL-6, IL-8 and TNF-α and conventional inflammatory parameters in the detection of metastatic forms of papillary thyroid cancer [PDF]
Objective: Inflammation is an important part of cancer pathophysiology. Preoperative detection of inflammatory parameters like cytokines and conventional inflammatory parameters (CIP), as well as their correlation, could be helpful in early detection of ...
S. Hodzic-Redzic+3 more
doaj +1 more source
CD20 and CD19 targeted vectors induce minimal activation of resting B lymphocytes [PDF]
B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors ...
A Pezzutto+51 more
core +6 more sources
Familial adenomatous polyposis (FAP) is an inherited disease characterized by the development of large number of colorectal adenomas with high risk of evolving into colorectal tumors. Mutations of the Adenomatous polyposis coli (APC) gene is often at the
Céline Cuche+27 more
doaj +1 more source
Hematopoiesis: A Layered Organization Across Chordate Species
The identification of distinct waves of progenitors during development, each corresponding to a specific time, space, and function, provided the basis for the concept of a “layered” organization in development.
Ramy Elsaid+28 more
doaj +1 more source
Lymphocytes in atherosclerosis [PDF]
It is well established that atherosclerosis is caused by an inflammatory process in the arterial intima. However, it is only in recent years that it has become clear that this inflammation is modulated by immune responses against plaque antigens. These antigens are primarily believed to be modified self-antigens such as oxidized LDL.
Wigren, Maria+2 more
openaire +5 more sources
STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia
Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly described ...
Marjolaine Debant+14 more
doaj +1 more source
Rheumatological features of Whipple disease
Whipple disease (WD) is a rare infectious systemic disease. Rheumatologists are at the frontline of WD diagnosis due to the early rheumatological manifestations. An early diagnosis is crucial, as usual anti-rheumatic drugs, especially TNF inhibitors, may
Alice Tison+16 more
doaj +1 more source
Discrimination of human cytotoxic lymphocytes from regulatory and B-lymphocytes by orthogonal light scattering [PDF]
Light scattering properties of human lymphocyte subpopulations selected by immunofluorescence were studied with a flow cytometer. Regulatory and B-lymphocytes showed a low orthogonal light scatter signal, whereas cytotoxic lymphocytes identified with leu-
Berkel, W. van+4 more
core +4 more sources