Results 31 to 40 of about 1,305,060 (334)

Crosstalk Between the Hepatic and Hematopoietic Systems During Embryonic Development

Frontiers in Cell and Developmental Biology, 2020
Hematopoietic stem cells (HSCs) generated during embryonic development are able to maintain hematopoiesis for the lifetime, producing all mature blood lineages.
Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Ana Cumano, Ana Cumano, Ana Cumano, Perpetua Pinto-do-Ó, Perpetua Pinto-do-Ó, Perpetua Pinto-do-Ó   +17 more
doaj   +1 more source

Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]

, 1975
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan, Boyum, Brunner, Calder, Cohen, Epstein, Evans, Fulginiti, Gardner, Gardner, Glasgow, Good, Hecht, Janossy, Julius, Koszinowski, Labowskie, Lohmann-Mathes, Lundstedt, Marker, McFarland, Oldstone, Perlmann, Perlmann, Profitt, Schirrmacher, Shearer, Shortman, Speel, Steele, Ueda, Ueda, Von Pirquet, Wagner, Wagner, Zinkernagel, Zinkernagel   +36 more
core   +1 more source

JAK Inhibitors and Oxidative Stress Control

Frontiers in Immunology, 2019
Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras, Pinelopi Arvaniti, Pinelopi Arvaniti, Pinelopi Arvaniti, Christelle Le Dantec, George N. Dalekos, George N. Dalekos, Kaliopi Zachou, Kaliopi Zachou, Anne Bordron, Yves Renaudineau, Yves Renaudineau   +11 more
doaj   +1 more source

Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules. [PDF]

, 1984
Normal and malignant lymphocytes can migrate from the bloodstream into lymph nodes and Peyer's patches. This process helps distribute normal lymphocytes throughout the lymphoid system and may provide a portal of entry for circulating malignant cells.
Rosen, SD, Stoolman, LM, Tenforde, TS
core   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen, Meng‐Meng Ji, Peng‐Peng Xu, Wei‐Li Zhao   +3 more
wiley   +1 more source

TIAger: Tumor-Infiltrating Lymphocyte Scoring in Breast Cancer for the TiGER Challenge [PDF]

arXiv, 2022
The quantification of tumor-infiltrating lymphocytes (TILs) has been shown to be an independent predictor for prognosis of breast cancer patients. Typically, pathologists give an estimate of the proportion of the stromal region that contains TILs to obtain a TILs score.
arxiv  

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

Coupling imaging mass cytometry with Alcian blue histochemical staining for a single-slide approach

Frontiers in Immunology
Imaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting ...
Patrice Hemon, Danivanh Ben-Guigui, Margaux Geier, Margaux Geier, Marine Castillon, Marine Castillon, Corentin Paranthoen, Corentin Paranthoen, Jacques-Olivier Pers, Marion Le Rochais, Arnaud Uguen, Arnaud Uguen   +11 more
doaj   +1 more source

A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL‐10 dependent derivatives of inflammatory monocytes

EMBO Molecular Medicine, 2013
Rhinoscleroma is a human specific chronic disease characterized by the formation of granuloma in the airways, caused by the bacterium Klebsiella pneumoniae subspecies rhinoscleromatis, a species very closely related to K. pneumoniae subspecies pneumoniae.
Cindy Fevre, Ana S. Almeida, Solenne Taront, Thierry Pedron, Michel Huerre, Marie‐Christine Prevost, Aurélie Kieusseian, Ana Cumano, Sylvain Brisse, Philippe J. Sansonetti, Régis Tournebize   +10 more
doaj   +1 more source

New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]

, 1975
New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J., Molday, Robert S., Rembaum, Alan, Yen, S. P. S.   +3 more
core   +2 more sources