Results 41 to 50 of about 1,988,114 (430)

A thermodynamical perspective of immune capabilities [PDF]

open access: yesJournal of Theoretical Biology 287 (2011) 48-63, 2011
We consider the mutual interactions, via cytokine exchanges, among helper lymphocytes, B lymphocytes and killer lymphocytes, and we model them as a unique system by means of a tripartite network. Each part includes all the different clones of the same lymphatic subpopulation, whose couplings to the others are either excitatory or inhibitory (mirroring ...
arxiv   +1 more source

Crosstalk Between the Hepatic and Hematopoietic Systems During Embryonic Development

open access: yesFrontiers in Cell and Developmental Biology, 2020
Hematopoietic stem cells (HSCs) generated during embryonic development are able to maintain hematopoiesis for the lifetime, producing all mature blood lineages.
Francisca Soares-da-Silva   +17 more
doaj   +1 more source

Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules. [PDF]

open access: yes, 1984
Normal and malignant lymphocytes can migrate from the bloodstream into lymph nodes and Peyer's patches. This process helps distribute normal lymphocytes throughout the lymphoid system and may provide a portal of entry for circulating malignant cells.
Rosen, SD, Stoolman, LM, Tenforde, TS
core   +1 more source

JAK Inhibitors and Oxidative Stress Control

open access: yesFrontiers in Immunology, 2019
Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras   +11 more
doaj   +1 more source

Morphologic observations of human T and B lymphocytes by scanning electron microscopy [PDF]

open access: yes, 1974
T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core   +1 more source

TIAger: Tumor-Infiltrating Lymphocyte Scoring in Breast Cancer for the TiGER Challenge [PDF]

open access: yesarXiv, 2022
The quantification of tumor-infiltrating lymphocytes (TILs) has been shown to be an independent predictor for prognosis of breast cancer patients. Typically, pathologists give an estimate of the proportion of the stromal region that contains TILs to obtain a TILs score.
arxiv  

Insights From Single Cell RNA Sequencing Into the Immunology of Type 1 Diabetes- Cell Phenotypes and Antigen Specificity

open access: yesFrontiers in Immunology, 2021
In the past few years, huge advances have been made in techniques to analyse cells at an individual level using RNA sequencing, and many of these have precipitated exciting discoveries in the immunology of type 1 diabetes (T1D).
Stephanie J. Hanna   +5 more
doaj   +1 more source

CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors [PDF]

open access: yes, 1988
The ability of memory T lymphocytes derived from latently infected mice to control murine cytomegalovirus disease in the immunocompromised host was studied by adoptive transfer experiments.
Jonjic, Stipan   +4 more
core   +1 more source

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

open access: yesThe Journal of Pathology: Clinical Research, 2021
Colorectal cancer (CRC) remains a leading cause of cancer mortality. Here, we define the colonic epithelial expression of cathelicidin (LL‐37) in CRC. Cathelicidin exerts pleotropic effects including anti‐microbial and immunoregulatory functions. Genetic
Ross J Porter   +9 more
doaj   +1 more source

Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]

open access: yes, 1975
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan   +36 more
core   +1 more source

Home - About - Disclaimer - Privacy